Zobrazeno 1 - 10
of 37 822
pro vyhledávání: '"GALEN"'
Autor:
Camille R. Simoneau, Pei-Yi Chen, Galen K. Xing, Jennifer M. Hayashi, Irene P. Chen, Mir M. Khalid, Nathan L. Meyers, Taha Y. Taha, Kristoffer E. Leon, Rahul K. Suryawanshi, Maria McCavitt-Malvido, Tal Ashuach, Krystal A. Fontaine, Lauren Rodriguez, Bastian Joehnk, Keith Walcott, Sreelakshmi Vasudevan, Xiaohui Fang, Mazharul Maishan, Shawn Schultz, Jeroen P. Roose, Michael A. Matthay, Anita Sil, Mehrdad Arjomandi, Nir Yosef, Melanie Ott
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract As SARS-CoV-2 continues to spread worldwide, tractable primary airway cell models that recapitulate the cell-intrinsic response to arising viral variants are needed. Here we describe an adult stem cell-derived human airway organoid model ove
Externí odkaz:
https://doaj.org/article/2b9300e935d0405aa6dbdcaf44fa0f99
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Policymakers at the federal and state level have begun to incorporate energy burden into equity goals and program evaluations, aiming to reduce energy burden below a high level of 6% for lower income households in the United States. Pairing
Externí odkaz:
https://doaj.org/article/8071362b90ca49b6bf57f851dea25b76
Publikováno v:
JAAD Case Reports, Vol 50, Iss , Pp 88-90 (2024)
Externí odkaz:
https://doaj.org/article/28658c70ed6840d680227226b24f79a7
Publikováno v:
Frontiers of Urban and Rural Planning, Vol 2, Iss 1, Pp 1-13 (2024)
Abstract Digital Twins (DTs) are increasingly recognized for their potential to improve efficiency and decision-making in various domains of the built environment. Despite their promise, challenges like cost, complexity, interoperability, and data in
Externí odkaz:
https://doaj.org/article/2dbd7e4844f142e9819efc755ddf32ae
Autor:
Jakob Hartmann, Thomas Bajaj, Joy Otten, Claudia Klengel, Tim Ebert, Anne-Kathrin Gellner, Ellen Junglas, Kathrin Hafner, Elmira A. Anderzhanova, Fiona Tang, Galen Missig, Lindsay Rexrode, Daniel T. Trussell, Katelyn X. Li, Max L. Pöhlmann, Sarah Mackert, Thomas M. Geiger, Daniel E. Heinz, Roy Lardenoije, Nina Dedic, Kenneth M. McCullough, Tomasz Próchnicki, Thomas Rhomberg, Silvia Martinelli, Antony Payton, Andrew C. Robinson, Valentin Stein, Eicke Latz, William A. Carlezon, Felix Hausch, Mathias V. Schmidt, Chris Murgatroyd, Sabina Berretta, Torsten Klengel, Harry Pantazopoulos, Kerry J. Ressler, Nils C. Gassen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract High levels of proinflammatory cytokines induce neurotoxicity and catalyze inflammation-driven neurodegeneration, but the specific release mechanisms from microglia remain elusive. Here we show that secretory autophagy (SA), a non-lytic moda
Externí odkaz:
https://doaj.org/article/83209dbad20940cdab3e3f6f4104353f
Autor:
Galen Royce-Nagel, MD, Mary Jarzebowski, MD, Pattrapun Wongsripuemtet, MD, Vijay Krishnamoorthy, MD, MPH, PhD, Matthew Fuller, MS, Tetsu Ohnuma, MD, MPH, PhD, Miriam Treggiari, MD, MPH, PhD, Miguel Yaport, MD, Julien Cobert, MD, Ethan Garrigan, MD, MPA, Raquel Bartz, MD, MMCi, MHA, Karthik Raghunathan, MD, MPH
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1105 (2024)
OBJECTIVES:. To describe the utilization of early ketamine use among patients mechanically ventilated for COVID-19, and examine associations with in-hospital mortality and other clinical outcomes. DESIGN:. Retrospective cohort study. SETTING:. Six hu
Externí odkaz:
https://doaj.org/article/dc406ff71f9f4302829e038e61f5f31a
Autor:
Lei Qin, Hongrui Qiu, Nori Nakata, Adam Booth, Zhendong Zhang, Marianne Karplus, John McKeague, Roger Clark, Galen Kaip
Publikováno v:
Geophysical Research Letters, Vol 51, Iss 12, Pp n/a-n/a (2024)
Abstract We construct a high‐resolution shear‐wave velocity (VS) model for the uppermost 100 m using ambient noise tomography near the West Antarctic Ice Sheet Divide camp. This is achieved via joint inversion of Rayleigh wave phase velocity and
Externí odkaz:
https://doaj.org/article/3125067d640342f78d1038003a575086
Autor:
Roberto Efraín Díaz, Andrew K Ecker, Galen J Correy, Pooja Asthana, Iris D Young, Bryan Faust, Michael C Thompson, Ian B Seiple, Steven Van Dyken, Richard M Locksley, James S Fraser
Publikováno v:
eLife, Vol 12 (2024)
Chitin is an abundant biopolymer and pathogen-associated molecular pattern that stimulates a host innate immune response. Mammals express chitin-binding and chitin-degrading proteins to remove chitin from the body. One of these proteins, Acidic Mamma
Externí odkaz:
https://doaj.org/article/1d6ac3d5e2914957b1f145449e49bd88
Autor:
Changjun Yu, Faqing Huang, Kinsley Wang, Mengmeng Liu, Warren A. Chow, Xiang Ling, Fengzhi Li, Jason L. Causey, Xiuzhen Huang, Galen Cook-Wiens, Xiaojiang Cui
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background The alkaloid camptothecin analog SN38 is a potent antineoplastic agent, but cannot be used directly for clinical application due to its poor water solubility. Currently, the prodrug approach on SN38 has resulted in 3 FDA-approved
Externí odkaz:
https://doaj.org/article/a56e557434774bd7afcb89fbdc19b1c1
Autor:
Nicholas B. Pohl, MS, Arjun Saxena, MD, MBA, Jeffrey B. Stambough, MD, John Ryan Martin, MD, Simon C. Mears, MD, PhD, Paul M. Lichstein, MD, MS, Eric Jordan, BS, Cameron R. Egan, MD, Antonia F. Chen, MD, MBA, Greg A. Erens, MD, Samir Chabib, MD, Bryce Wall, MD, Navin D. Fernando, MD, Jordan Nichols, MD, Ran Schwarzkopf, MD, MSc, Katherine A. Lygrisse, MD, Derek F. Amanatullah, MD, PhD, Prerna Arora, MTech, David Ivanov, MD, Galvin Loughran, James Browne, MD, Danielle Hogarth, BS, Parke Hudson, MD, Thomas K. Donaldson, MD, Frank Buttacavoli, MD, Ravi Kari, MD, Galen Mills, MD
Publikováno v:
Arthroplasty Today, Vol 29, Iss , Pp 101428- (2024)
Background: Periprosthetic femur fractures (PPFFs) following total hip arthroplasty (THA) have increased in the past decade as the demand for primary surgery continues to grow. Although there is now more evidence to describe the treatment of Vancouve
Externí odkaz:
https://doaj.org/article/a5f002caf4be4d9bb8a3d96ce4c07bae