Zobrazeno 1 - 10
of 28
pro vyhledávání: '"GAD-Glutamic acid decarboxylase"'
Autor:
Chandra Mohan Sharma, Rajendra Kumar Pandey, Banshi Lal Kumawat, Dinesh Khandelwal, Pankaj Gandhi
Publikováno v:
Annals of Indian Academy of Neurology, Vol 19, Iss 1, Pp 146-149 (2016)
Antibodies to GAD-65 have been implicated in the pathogenesis of type 1 diabetes , limbic encephalitis and Stiff person syndrome, however these diseases rarely occur concurrently. We intend to present a rare case of 35 year old female who was recentl
Externí odkaz:
https://doaj.org/article/b6c062b688f64c3da4bc00cae8fa6ed9
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1347-1359 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1347-1359 (2020)
Gene therapy is rapidly emerging as a powerful therapeutic strategy for a wide range of neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease (PD) and Huntington's disease (HD). Some early clinical trials have failed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b140cd71516f9b1622ac1023338efec
https://doi.org/10.1016/j.apsb.2020.01.015
https://doi.org/10.1016/j.apsb.2020.01.015
Autor:
Koh, Pei Xuan, Tay, Kay Yaw, Yeo, Tianrong, Singh, Dinesh Rambachan, Koh, Jasmine Shimin, Thirugnanam, Umapathi N, Saini, Monica
Publikováno v:
Neuroimmunology Reports
Background Literature describing triggers of GFAP astrocytopathy (GFAP-A) is limited. We report a case of GFAP-A in a patient with recent messenger ribonucleic acid (mRNA) severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) vaccination and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697e90deaf481dd15d7f20a034db37d7
https://doi.org/10.1016/j.nerep.2021.100053
https://doi.org/10.1016/j.nerep.2021.100053
Autor:
Audris Chiang, Ashley N. Elsensohn, Janellen Smith, Sebastien de Feraudy, Lance W. Chapman, Jessica Shiu
Publikováno v:
JAAD Case Reports, Vol 4, Iss 4, Pp 295-297 (2018)
JAAD Case Reports
JAAD Case Reports
Author(s): Chiang, Audris; Shiu, Jessica; Elsensohn, Ashley N; Chapman, Lance W; de Feraudy, Sebastien; Smith, Janellen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcff67e21cf731d74dfb94b5cf86257
http://www.sciencedirect.com/science/article/pii/S2352512617302515
http://www.sciencedirect.com/science/article/pii/S2352512617302515
Publikováno v:
The Journal of Biological Chemistry
Mitochondria are critical for regulation of the activation, differentiation, and survival of macrophages and other immune cells. In response to various extracellular signals, such as microbial or viral infection, changes to mitochondrial metabolism a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b40b8a29dfcab6952141869277a440
https://doi.org/10.1016/j.jbc.2021.100904
https://doi.org/10.1016/j.jbc.2021.100904
Autor:
Yunbing Shen, Anatoly Dubnovitsky, Zsolt Kasza, Maria Bettini, Sanjay V. Boddul, William W. Kwok, Vivianne Malmström, Bruno Raposo, Aaron Winkler, Lars Klareskog, Ravi Sharma, Vaishnavi Srinivasan Iyer, Fredrik Wermeling, Christina Gerstner
Publikováno v:
Journal of Translational Autoimmunity
Journal of Translational Autoimmunity, Vol 4, Iss, Pp 100087-(2021)
Journal of Translational Autoimmunity, Vol 4, Iss, Pp 100087-(2021)
Recent advances in single-cell sequencing technologies enable the generation of large-scale data sets of paired TCR sequences from patients with autoimmune disease. Methods to validate and characterize patient-derived TCR data are needed, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4ec6f35bd5ce462fdebe9813a58868
https://doi.org/10.1016/j.jtauto.2021.100087
https://doi.org/10.1016/j.jtauto.2021.100087
Publikováno v:
Epilepsy & Behavior Reports
Epilepsy & Behavior Reports, Vol 14, Iss, Pp 100396-(2020)
Epilepsy & Behavior Reports, Vol 14, Iss, Pp 100396-(2020)
Highlights • Anti-glutamic acid decarboxylase (GAD) antibodies cause limbic encephalitis. • Super refractory status epilepticus can be a manifestation of anti-GAD encephalitis. • Rapid treatment with tocilizumab immunological polytherapy may im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182831eb8e22fc8d28213490046bcfa0
https://doi.org/10.1016/j.ebr.2020.100396
https://doi.org/10.1016/j.ebr.2020.100396
Publikováno v:
Neurobiology of Disease, 69, 225-234
Neurobiology of Disease, Vol 69, Iss, Pp 225-234 (2014)
Neurobiology of Disease
Neurobiology of Disease, Vol 69, Iss, Pp 225-234 (2014)
Neurobiology of Disease
Familial hemiplegic migraine type 1 (FHM1), a monogenic subtype of migraine with aura, is caused by gain-of-function mutations in CaV2.1 (P/Q-type) calcium channels. In FHM1 knockin mice, excitatory neurotransmission at cortical pyramidal cell synaps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1a4bd9c75676a109bc4b63ad20d0a7
Autor:
Vanderlugt, Carol J, Miller, Stephen D
Publikováno v:
Current Opinion in Immunology
Epitope (determinant) spreading is the development of immune responses to endogenous epitopes secondary to the release of self antigens during a chronic autoimmune or inflammatory response. The past year has seen considerable advances in our understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77ababa4ccf4c55e977842bdb301cdd
https://doi.org/10.1016/s0952-7915(96)80012-4
https://doi.org/10.1016/s0952-7915(96)80012-4
Autor:
Anders Sm Wong, Trevor Key, Carlos J. Rosado, Robert N. Pike, Gustavo Fenalti, Ruby H. P. Law, James C. Whisstock, Christopher G. Langendorf, Ashley M. Buckle, Kellie L. Tuck
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 33, Iss 1, p e00013 (2013)
Bioscience Reports, Vol 33, Iss 1, p e00013 (2013)
Imbalances in GABA (γ-aminobutyric acid) homoeostasis underlie psychiatric and movement disorders. The ability of the 65 kDa isoform of GAD (glutamic acid decarboxylase), GAD65, to control synaptic GABA levels is influenced through its capacity to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed270ef40f18d2a0159a472771aa178
https://pubmed.ncbi.nlm.nih.gov/23126365
https://pubmed.ncbi.nlm.nih.gov/23126365