Zobrazeno 1 - 10
of 89
pro vyhledávání: '"GABRIELLA NICOLINI"'
Autor:
Mirko Rivara, Gabriella Nicolini, Alessio Malacrida, Francesca Re, Matteo Incerti, Giulia Russo, Valentina Zuliani
Publikováno v:
Results in Chemistry, Vol 9, Iss , Pp 101645- (2024)
Purpose: Glioblastoma is an aggressive brain tumor with high mortality and a median survival of about 15 months. Starting from our previous published compound, MV1035 that inhibited migration and invasiveness of glioblastoma U87 cells, and also exhib
Externí odkaz:
https://doaj.org/article/2d9efe51fe1c49b39ca8df427982e0b3
Autor:
Andrea Anichini, Alessandra Molla, Gabriella Nicolini, Valentina Eleonora Perotti, Francesco Sgambelluri, Alessia Covre, Carolina Fazio, Maria Fortunata Lofiego, Anna Maria Di Giacomo, Sandra Coral, Antonella Manca, Maria Cristina Sini, Marina Pisano, Teresa Noviello, Francesca Caruso, Silvia Brich, Giancarlo Pruneri, Andrea Maurichi, Mario Santinami, Michele Ceccarelli, Giuseppe Palmieri, Michele Maio, Roberta Mortarini, On behalf of the EPigenetic Immune-oncology Consortium AIRC (EPICA) investigators
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-15 (2022)
Abstract Background Improvement of efficacy of immune checkpoint blockade (ICB) remains a major clinical goal. Association of ICB with immunomodulatory epigenetic drugs is an option. However, epigenetic inhibitors show a heterogeneous landscape of ac
Externí odkaz:
https://doaj.org/article/79c74f16caf34f389f373906c070b84d
Publikováno v:
Biology, Vol 13, Iss 1, p 61 (2024)
Chemotherapy-induced peripheral neuropathy (CIPN) commonly arises as a side effect of diverse cancer chemotherapy treatments. This condition presents symptoms such as numbness, tingling, and altered sensation in patients, often accompanied by neuropa
Externí odkaz:
https://doaj.org/article/fc4f41efa1fc410c96f5dcecba71db8d
Publikováno v:
Biology, Vol 11, Iss 7, p 1041 (2022)
5′-adenosine monophosphate (AMP)-activated protein kinase (AMPK) is an enzyme that regulates cellular energy homeostasis, glucose, fatty acid uptake, and oxidation at low cellular ATP levels. AMPK plays an important role in several molecular mechan
Externí odkaz:
https://doaj.org/article/0a65157f83fc45149b2f4a2f8ae071b1
Autor:
Alessio Malacrida, Alessandro Di Domizio, Angela Bentivegna, Giacomo Cislaghi, Eleonora Messuti, Silvia Maria Tabano, Carlo Giussani, Valentina Zuliani, Mirko Rivara, Gabriella Nicolini
Publikováno v:
Biology, Vol 11, Iss 1, p 70 (2022)
Glioblastoma (GBM, grade IV glioma) represents the most aggressive brain tumor and patients with GBM have a poor prognosis. Until now surgical resection followed by radiotherapy and temozolomide (TMZ) treatment represents the standard strategy for GB
Externí odkaz:
https://doaj.org/article/a4e6c4c6db6e4789b9660898c8c48d39
Publikováno v:
Toxics, Vol 3, Iss 3, Pp 322-341 (2015)
Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a dose-limiting side effect of several antineoplastic drugs which significantly reduces patients’ quality of life. Although different molecular mechanisms have been investigated, CIPN pathobiolog
Externí odkaz:
https://doaj.org/article/af429e373ad041219fa2501109e6b31e
Autor:
Alessio Malacrida, Valeria Cavalloro, Emanuela Martino, Arianna Cassetti, Gabriella Nicolini, Roberta Rigolio, Guido Cavaletti, Barbara Mannucci, Francesca Vasile, Marcello Di Giacomo, Simona Collina, Mariarosaria Miloso
Publikováno v:
Molecules, Vol 24, Iss 13, p 2500 (2019)
Multiple myeloma (MM) belongs to hematological cancers and its incidence is increasing worldwide. Despite recent advances in its therapy, MM still causes many deaths every year. In fact, current therapies sometimes fail and are associated with severe
Externí odkaz:
https://doaj.org/article/e142ee31a73c4959b6725d7730aa71d2
Autor:
Alessia Chiorazzi, Gabriella Nicolini, Annalisa Canta, Norberto Oggioni, Roberta Rigolio, Giacomo Cossa, Raffaella Lombardi, Ilaria Roglio, Ilaria Cervellini, Giuseppe Lauria, Roberto Cosimo Melcangi, Roberto Bianchi, Donatella Crippa, Guido Cavaletti
Publikováno v:
Neurobiology of Disease, Vol 35, Iss 2, Pp 270-277 (2009)
Epothilones are a novel class of microtubule-targeting anticancer agents that are neurotoxic. In this study, we investigated the epothilone B toxic effect in vitro and we characterized in vivo the general and neurological side effects of epothilone B
Externí odkaz:
https://doaj.org/article/d6bad2faf5fc43f782ebfdbb2ced6031
Publikováno v:
Oncology Reviews, Vol 5, Iss 4 (2011)
Cancer of head and neck (HN) represents a diffused group of neoplasia; despite advances in clinical treatment its mortality rate has remained high, mainly because it is frequently diagnosed only at an advanced stage. Molecular markers allowing the di
Externí odkaz:
https://doaj.org/article/37d9fd3f248044ab8a853f9d976ed054
Autor:
Elisa Ballarini, Alessio Malacrida, Virginia Rodriguez-Menendez, Eleonora Pozzi, Annalisa Canta, Alessia Chiorazzi, Laura Monza, Sara Semperboni, Cristina Meregalli, Valentina Alda Carozzi, Maryamsadat Hashemi, Gabriella Nicolini, Arianna Scuteri, Stephen N. Housley, Guido Cavaletti, Paola Alberti
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 10063
Oxaliplatin (OHP)-induced peripheral neurotoxicity (OIPN) is a frequent adverse event of colorectal cancer treatment. OIPN encompasses a chronic and an acute syndrome. The latter consists of transient axonal hyperexcitability, due to unbalance in Na+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a907bacb5dfae997b96f3058248b72b7
http://hdl.handle.net/10281/391608
http://hdl.handle.net/10281/391608
