Zobrazeno 1 - 10
of 3 277
pro vyhledávání: '"GABRIELE M."'
Autor:
Wen Du, Suyash Mishra, James G. Ogg, Yuzheng Qian, Sabrina Chang, Karan Oberoi, Aaron Ault, Sabin Zahirovic, Hongfei Hou, D. S. N. Raju, O’Neil Mamallapalli, Gabriele M. Ogg, Haipeng Li, Christopher R. Scotese, Bui Dong
Publikováno v:
Geoscience Data Journal, Vol 11, Iss 4, Pp 1044-1057 (2024)
Abstract Paleogeography is the merger of sediment and volcanic facies, depositional settings, tectonic plate movements, topography, climate patterns and ecosystems through time. The construction of paleogeographic maps on tectonic plate reconstructio
Externí odkaz:
https://doaj.org/article/a7a6d9e472fe4785ada9a4d0686c60a4
Autor:
Edda S. F. Matthees, Jenny C. Filor, Natasha Jaiswal, Mona Reichel, Noureldine Youssef, Giulia D’Uonnolo, Martyna Szpakowska, Julia Drube, Gabriele M. König, Evi Kostenis, Andy Chevigné, Amod Godbole, Carsten Hoffmann
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract G protein-coupled receptors (GPCRs) are mainly regulated by GPCR kinase (GRK) phosphorylation and subsequent β-arrestin recruitment. The ubiquitously expressed GRKs are classified into cytosolic GRK2/3 and membrane-tethered GRK5/6 subfamili
Externí odkaz:
https://doaj.org/article/96a45090aeee491db5f90c0458558dd1
Publikováno v:
Rambam Maimonides Medical Journal, Vol 15, Iss 1, p e0001 (2024)
Coronary artery bypass grafting (CABG) is the most commonly performed and studied major cardiac operation worldwide. An understanding of the evolution of CABG, including the early days of cardiac surgery, the first bypass operation, continuous improv
Externí odkaz:
https://doaj.org/article/72836c7ad4294b649f97bf00574937e7
Autor:
Vyara Todorova, Luca Merolla, Duygu Karademir, Gabriele M. Wögenstein, Julian Behr, Lynn J. A. Ebner, Marijana Samardzija, Christian Grimm
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Understanding the physiology of the retina, and especially of the highly polarized photoreceptors, is essential not only to broaden our knowledge of the processes required for normal vision, but also to develop effective therapies to prevent
Externí odkaz:
https://doaj.org/article/4755d8b2082a466ba07c645babee31e3
Autor:
Jan H. Voss, Max Crüsemann, Christian R.O. Bartling, Stefan Kehraus, Asuka Inoue, Gabriele M. König, Kristian Strømgaard, Christa E. Müller
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106492- (2023)
Summary: The macrocyclic depsipeptides YM-254890 (YM) and FR900359 (FR) are potent inhibitors of Gαq/11 proteins. They are important pharmacological tools and have potential as therapeutic drugs. The hydrogenated, tritium-labeled YM and FR derivativ
Externí odkaz:
https://doaj.org/article/2a7281d6a7c5400a9b68ae13982ff5b1
Autor:
Gabriele M. Linke
Publikováno v:
European Journal of Life Writing, Vol 12, Pp C21-C26 (2023)
This three-part collection of personal memories was inspired by Otto Dix's triptych ‘The War’ (1929-1932). The horrors of war and presence of death Dix exposed in his painting form the implicit point of reference for three short stories of reconc
Externí odkaz:
https://doaj.org/article/be0bed6120e84fd9913be15b460a87cc
Autor:
Ahmed Wagdi, Daniela Malan, Udhayabhaskar Sathyanarayanan, Janosch S. Beauchamp, Markus Vogt, David Zipf, Thomas Beiert, Berivan Mansuroglu, Vanessa Dusend, Mark Meininghaus, Linn Schneider, Bernd Kalthof, J. Simon Wiegert, Gabriele M. König, Evi Kostenis, Robert Patejdl, Philipp Sasse, Tobias Bruegmann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Gq proteins are one of four major classes of G proteins; optogenetic receptors for selective and repetitive activation of Gq proteins with fast kinetics are lacking. Here the authors report UV light-dependent Gq signalling using human Neuropsin (hOPN
Externí odkaz:
https://doaj.org/article/a279b477c4f4465bb0b225dabc9ba09a
Autor:
Takefumi Kimura, Sai P. Pydi, Lei Wang, Dhanush Haspula, Yinghong Cui, Huiyan Lu, Gabriele M. König, Evi Kostenis, Gregory R. Steinberg, Oksana Gavrilova, Jürgen Wess
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Obesity impairs regulation of adipocyte lipolysis, which contributes towards development of insulin resistance. Here the authors report that adipocyte Gq signaling functions as a regulator of lipolysis and systemic glucose and lipid homeostasis in mi
Externí odkaz:
https://doaj.org/article/f0d1158d61ee4a5a901478e2a9b74e39
Autor:
Margaret E. Maes, Gabriele M. Wögenstein, Gloria Colombo, Raquel Casado-Polanco, Sandra Siegert
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 210-224 (2021)
Adeno-associated viruses (AAVs) are widely used to deliver genetic material in vivo to distinct cell types such as neurons or glial cells, allowing for targeted manipulation. Transduction of microglia is mostly excluded from this strategy, likely due
Externí odkaz:
https://doaj.org/article/8e7352fa5ae14417bfd0e187c5d96c5c
Autor:
Gabriele M. Iacona, MD, Shrey Patel, MD, Faisal G. Bakaeen, MD, Hiba Ghandour, MD, Robert D. Stewart, MD, Lars G. Svensson, MD, PhD, Gösta B. Pettersson, MD, PhD, Douglas R. Johnston, MD
Publikováno v:
JACC: Case Reports, Vol 4, Iss 24, Pp 101665- (2022)
Surgical treatment of aneurysmal distal congenital coronary artery fistulas depends on size and anatomy. From 2008 to 2021, we applied a new surgical technique in 7 adult patients: proximal and distal fistula closure, opening of aneurysmal artery, an
Externí odkaz:
https://doaj.org/article/19e812e232504689a119eef3571cfeca