Zobrazeno 1 - 10
of 265
pro vyhledávání: '"GABAergic synapse"'
Publikováno v:
Environmental Science and Ecotechnology, Vol 21, Iss , Pp 100437- (2024)
The coexistence of caffeine (CF) and ketamine (KET) in surface waters across Asia has been widely reported. Previous studies have implied that CF and KET may share a mechanism of action. However, the combined toxicity of these two chemicals on aquati
Externí odkaz:
https://doaj.org/article/a1d0bcc3c15c4160bfab9c51eadbd2e4
Autor:
Yusheng Sui, Martin Mortensen, Banghao Yuan, Martin W. Nicholson, Trevor G. Smart, Jasmina N. Jovanovic
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
GABAA receptors (γ-aminobutyric acid-gated receptors type A; GABAARs), the major structural and functional postsynaptic components of inhibitory synapses in the mammalian brain, belong to a family of GABA-gated Cl−/HCO3− ion channels. They are a
Externí odkaz:
https://doaj.org/article/529b606f5b0f412881dc9abf0b3d1af1
Publikováno v:
Medical Review, Vol 4, Iss 1, Pp 31-41 (2024)
Down syndrome (DS) is caused by the presence of an extra copy of the entire or a portion of human chromosome 21 (HSA21). This genomic alteration leads to elevated expression of numerous HSA21 genes, resulting in a variety of health issues in individu
Externí odkaz:
https://doaj.org/article/5afd7facec7948f09f612e4cb09c8b80
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 12, Pp 2698-2707 (2024)
Gamma-aminobutyric acid (GABA)ergic neurons, the most abundant inhibitory neurons in the human brain, have been found to be reduced in many neurological disorders, including Alzheimer’s disease and Alzheimer’s disease-related dementia. Our previo
Externí odkaz:
https://doaj.org/article/eb60dd80ad1047f286fe1d7865cd73cf
Autor:
Nicolas Chofflet, Yusuke Naito, Anthony John Pastore, Nirmala Padmanabhan, Phuong Trang Nguyen, Christian Poitras, Benjamin Feller, Nayoung Yi, Jeremie Van Prooijen, Husam Khaled, Benoit Coulombe, Steven J. Clapcote, Steve Bourgault, Tabrez J. Siddiqui, Gabby Rudenko, Hideto Takahashi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The prevailing model behind synapse development and specificity is that a multitude of adhesion molecules engage in transsynaptic interactions to induce pre- and postsynaptic assembly. How these extracellular interactions translate into intracellular
Externí odkaz:
https://doaj.org/article/b0e5ea6d61414d33a1c87b6f1bb93555
Autor:
Stephanie Efthymiou, Wenyan Han, Muhammad Ilyas, Jun Li, Yichao Yu, Marcello Scala, Nancy T. Malintan, Nikoleta Vavouraki, Kshitij Mankad, Reza Maroofian, Clarissa Rocca, Vincenzo Salpietro, Shenela Lakhani, Eric J. Mallack, Timothy Blake Palculict, Hong Li, Guojun Zhang, Faisal Zafar, Nuzhat Rana, Noriko Takashima, Hayato Matsunaga, Claudia Manzoni, Pasquale Striano, Mark F. Lythgoe, Jun Aruga, Wei Lu, Henry Houlden
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
This study reports on biallelic homozygous and monoallelic de novo variants in SLITRK3 in three unrelated families presenting with epileptic encephalopathy associated with a broad neurological involvement characterized by microcephaly, intellectual d
Externí odkaz:
https://doaj.org/article/4c9fba0e92c64e6881b4e82760b9b3c3
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Hongxiu Zhang, Xiaoyan Xue, Jin Pan, Xiaobin Song, Xing Chang, Qiancheng Mao, Yanting Lu, Haijun Zhao, Yuan Wang, Xiansu Chi, Shijun Wang, Ke Ma
Publikováno v:
Chinese Medicine, Vol 16, Iss 1, Pp 1-28 (2021)
Abstract Background Lily Bulb and Rehmannia Decoction (LBRD), is a traditional Chinese formula that has been shown to be safe and effective against depression; however, its material basis and pharmacological mechanisms remain unknown. Methods Here, u
Externí odkaz:
https://doaj.org/article/c536809d6ab349abb3d70b17fca12f49
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Comprehensive electrophysiological characterizations of human induced pluripotent stem cell (hiPSC)-derived neuronal networks are essential to determine to what extent these in vitro models recapitulate the functional features of in vivo neuronal cir
Externí odkaz:
https://doaj.org/article/4abadc087acd4969b83eb6dfed7f23e4