Zobrazeno 1 - 10
of 133
pro vyhledávání: '"GABA transaminase inhibitor"'
Autor:
Jing Ji, Wei Chen, Lanzhen Chen, Jianyun Yue, Tiantian Xie, Zeping Jiang, Shengqing Shi, Changjian Du, Jiacheng Sun
Publikováno v:
Journal of Experimental Botany. 71:1459-1474
γ-Aminobutyric acid (GABA) influences plant growth, but little is known about how this metabolite regulates adventitious root (AR) development. Here, we investigate the effects of GABA on ARs using poplar lines overexpressing glutamate decarboxilase
Publikováno v:
Fundamental & Clinical Pharmacology. 32:485-498
We have previously shown that cyclosporine (CSA) counteracts cardiovascular manifestations induced by endotoxemia (lipopolysaccharide, LPS) such as hypotension and cardiac autonomic dysfunction in conscious rats. In this study, we investigated whethe
Akademický článek
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Autor:
Lin Chen, Xiao-Peng Liu
Publikováno v:
Hearing Research. 323:51-60
We recently reported that forward acoustic masking can enhance the auditory brainstem response (ABR) in rats treated with a high dose of sodium salicylate (NaSal), a tinnitus inducer, when tested in open acoustic field ( Liu and Chen, 2012 , Brain Re
Akademický článek
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Autor:
Mitsuru Kawaguchi, Migiwa Okubo
Publikováno v:
Journal of Pharmacological Sciences, Vol 122, Iss 1, Pp 42-50 (2013)
GABA is an inhibitory transmitter found in rat salivary gland. However, the inhibitory potential of GABA on salivary secretion is unclear. Using an in vivo cannulation method, intraperitoneal administration of GABA was ineffective in the absence of g
Publikováno v:
Pediatric neurology. 66
Background Gamma-vinyl–γ-aminobutyric acid (GABA) (vigabatrin) is an antiepileptic drug and irreversible GABA transaminase inhibitor associated with visual field impairment, which limits its clinical utility. We sought to relate altered visual evo
Publikováno v:
Behavioural Pharmacology. 23:178-190
We tested the hypothesis that the irreversible gamma-amino butyric acid (GABA) transaminase inhibitor, γ-vinyl GABA (Vigabatrin; VGB) would reduce ethanol reinforcement and enhance the discriminative stimulus effect of ethanol, effectively reducing
Autor:
Rafael Martín-del-Río, M Braun, Inés Hernández-Fisac, Jorge Tamarit-Rodriguez, Javier Pizarro-Delgado
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2010, 431 (3), pp.381-389. ⟨10.1042/BJ20100714⟩
Biochemical Journal, Portland Press, 2010, 431 (3), pp.381-389. ⟨10.1042/BJ20100714⟩
We have demonstrated recently that branched-chain α-keto acid stimulation of insulin secretion is dependent on islet GABA (γ-aminobutyric acid) metabolism: GABA transamination to succinic semialdehyde is increased by 2-oxoglutarate, generated in α
Autor:
Krassimira Yakimova, Rumen Nikolov
Publikováno v:
Amino Acids. 40:1441-1445
Vigabatrin is a GABA derivative (gamma-vinyl GABA) which inhibits irreversibly the enzyme activity of GABA transaminase and thus increased indirectly brain GABA concentrations. We have used body temperature assay to examine the effects of Vigabatrin