Zobrazeno 1 - 10
of 37
pro vyhledávání: '"GABA switch"'
Autor:
Daniel J. Schill, Durga Attili, Cynthia J. DeLong, Melvin G. McInnis, Craig N. Johnson, Geoffrey G. Murphy, K. Sue O’Shea
Publikováno v:
Cells, Vol 13, Iss 14, p 1194 (2024)
Bipolar disorder (BP) is a recurring psychiatric condition characterized by alternating episodes of low energy (depressions) followed by manias (high energy). Cortical network activity produced by GABAergic interneurons may be critical in maintaining
Externí odkaz:
https://doaj.org/article/b9ab77d288854f43a2d082a81adb890c
Autor:
Alexander M. Kleschevnikov
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The most distinctive feature of Down syndrome (DS) is moderate to severe cognitive impairment. Genetic, molecular, and neuronal mechanisms of this complex DS phenotype are currently under intensive investigation. It is becoming increasingly clear tha
Externí odkaz:
https://doaj.org/article/09ca4e58ed454820a6dc1774474aa802
Akademický článek
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Autor:
Larisa V. Lysenko, Jeesun Kim, Francisco Madamba, Anna A. Tyrtyshnaia, Aarti Ruparelia, Alexander M. Kleschevnikov
Publikováno v:
Neurobiology of Disease, Vol 115, Iss , Pp 1-8 (2018)
Down syndrome (DS) is the most frequent genetic cause of developmental abnormalities leading to intellectual disability. One notable phenomenon affecting the formation of nascent neural circuits during late developmental periods is developmental swit
Externí odkaz:
https://doaj.org/article/7989499b4128411ca00c91bb376df0ee
Publikováno v:
Frontiers in Human Neuroscience, Vol 11 (2017)
Previous models or hypotheses of autism spectral disorder (ASD) failed to take into full consideration the chronological and causal developmental trajectory, leading to the emergence of diverse phenotypes through a complex interaction between individ
Externí odkaz:
https://doaj.org/article/dbb89d4fca5c4a24808f8a8e30791515
Publikováno v:
Frontiers in Neural Circuits, Vol 7 (2013)
Neuronal networks in vitro are prominent systems to study the development of connections in living neuronal networks and the interplay between connectivity, activity and function. These cultured networks show a rich spontaneous activity that evolves
Externí odkaz:
https://doaj.org/article/2f663aec639642e2b8d048efd3cb571e
This paper presents a new time-varying long-term Synaptic Efficacy Function-based leaky-integrate-and-fire neuRON model, referred to as SEFRON and its supervised learning rule for pattern classification problems. The time-varying synaptic efficacy fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826a2ae370b9313cf17ed5a220c22794
https://hdl.handle.net/10356/144620
https://hdl.handle.net/10356/144620
Autor:
Raffaella Morini, Elisa Focchi, Michela Matteoli, Romana Tomasoni, Riccardo Fesce, Elsa Ghirardini, Diego Morone, Michela Lizier, Marco Rasile, Davide Pozzi, Irene Corradini, Flavia Antonucci, Isabella Barajon, Genni Desiato
Background The association between maternal infection and neurodevelopmental defects in progeny is well established, although the biological mechanisms and the pathogenic trajectories involved have not been defined. Methods Pregnant dams were injecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d529b3973236aedcece770edd5f97d
http://hdl.handle.net/11383/2069061
http://hdl.handle.net/11383/2069061
Akademický článek
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Akademický článek
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