Zobrazeno 1 - 10
of 398
pro vyhledávání: '"GABA metabolism"'
Autor:
Yuchen Qin, Weiyu Huang, Zijiang Wang, Chunting Wang, Chen Wang, Meng Zhang, Shengting Wu, Gaoyang Wang, Fenghong Zhao
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 279, Iss , Pp 116464- (2024)
1,2-Dichloroethane (1,2-DCE) is a powerfully toxic neurotoxin, which is a common environmental pollutant. Studies have indicated that 1,2-DCE long-term exposure can result in adverse effects. Nevertheless, the precise mechanism remains unknown. In th
Externí odkaz:
https://doaj.org/article/35079e99d9a74b6b8aa3dca860021655
Autor:
Wardiya Afshar-Saber, Nicole A. Teaney, Kellen D. Winden, Hellen Jumo, Xutong Shi, Gabrielle McGinty, Jed Hubbs, Cidi Chen, Itay Tokatly Latzer, Federico Gasparoli, Darius Ebrahimi-Fakhari, Elizabeth D. Buttermore, Jean-Baptiste Roullet, Phillip L. Pearl, Mustafa Sahin
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106386- (2024)
Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a neurometabolic disorder caused by ALDH5A1 mutations presenting with autism and epilepsy. SSADHD leads to impaired GABA metabolism and results in accumulation of GABA and γ-hydroxybutyrate
Externí odkaz:
https://doaj.org/article/6afdfd05e9854926bfb6dac05d7d20fc
Akademický článek
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Autor:
Jorge Tamarit-Rodriguez
Publikováno v:
Metabolites, Vol 13, Iss 6, p 697 (2023)
The stimulus-secretion coupling of a glucose-induced release is generally attributed to the metabolism of the hexose in the β-cells in the glycolytic pathway and the citric acid cycle. Glucose metabolism generates an increased cytosolic concentratio
Externí odkaz:
https://doaj.org/article/eee4c34bb35c4b94a42fe97e4a3c39f8
Autor:
Malwina Lisek, Joanna Mackiewicz, Marta Sobolczyk, Bozena Ferenc, Feng Guo, Ludmila Zylinska, Tomasz Boczek
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
PMCA2 is not expressed until the late embryonic state when the control of subtle Ca2+ fluxes becomes important for neuronal specialization. During this period, immature neurons are especially vulnerable to degenerative insults induced by the N-methyl
Externí odkaz:
https://doaj.org/article/fd91a89f4ff64c9589947b716d815dc6
Akademický článek
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Publikováno v:
Agronomy, Vol 12, Iss 7, p 1577 (2022)
Alfalfa (Medicago sativa L.) is a widely grown and important forage crop. However, alkali stress is detrimental to alfalfa yield and nutritional quality. Gamma-aminobutyric acid (GABA) is a signaling molecule, it participates in and responds to metab
Externí odkaz:
https://doaj.org/article/dc34057f4f844c979bf6c5437def8838
Autor:
Jens V. Andersen, Sofie K. Christensen, Emil W. Westi, Marta Diaz-delCastillo, Heikki Tanila, Arne Schousboe, Blanca I. Aldana, Helle S. Waagepetersen
Publikováno v:
Neurobiology of Disease, Vol 148, Iss , Pp 105198- (2021)
Alzheimer's disease (AD) leads to cerebral accumulation of insoluble amyloid-β plaques causing synaptic dysfunction and neuronal death. Neurons rely on astrocyte-derived glutamine for replenishment of the amino acid neurotransmitter pools. Perturbat
Externí odkaz:
https://doaj.org/article/7c5b4141f2994d0882f66f444ab669c0
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Over the last seven decades, γ-aminobutyric acid (GABA) has attracted great attention from scientists for its ubiquity in plants, animals and microorganisms and for its physiological implications as a signaling molecule involved in multiple pathways
Externí odkaz:
https://doaj.org/article/2ad956dfa0c042dba484cb357f2df089
Publikováno v:
Plants, Vol 10, Iss 10, p 2178 (2021)
The signaling role for γ-Aminobutyric acid (GABA) has been documented in animals for over seven decades. However, a signaling role for GABA in plants is just beginning to emerge with the discovery of putative GABA binding site/s and GABA regulation
Externí odkaz:
https://doaj.org/article/65cb4f26027c44e2a01436b50ca790f0