Výsledky vyhledávání - "GABA analogue"

Non‐medical use of benzodiazepines and GABA analogues in Europe

Autor: Colleen M. Haynes, Joshua C. Black, David M. Wood, Elise Amioka, Joanna Hockenhull, Richard C. Dart, Paul I. Dargan, Alyssa Forber

Publikováno v: British Journal of Clinical Pharmacology. 87:1684-1694

AIMS We investigated the prevalence of non-medical use (NMU) of benzodiazepines and GABA analogues in Europe. METHODS Data were collected using the online Non-Medical Use of Prescription Drugs (NMURx) survey from France, Germany, Italy, Spain and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d543d0f362980af676905e9a1de23daf
https://doi.org/10.1111/bcp.14537

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Autor: Kathrin Hobron, Trista H. Wright, Amy M. Tharp

Publikováno v: Journal of Forensic Sciences. 64:1105-1111

Gabapentin, a GABA analogue, is a nonopioid prescribed for seizure control and neuralgic pain. Its abuse for recreational purposes has been increasing in recent years as the number of prescriptions also increases. In our series, we review 104 cases o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838ec9fc7b1539c0a00300f89ba56f4d
https://doi.org/10.1111/1556-4029.14021

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Gabapentin – 8 reasons to use in pain management the reliable GABA analogue

Autor: Magdalena Kocot-Kępska

Publikováno v: Medycyna Faktów. 11:194-198

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b2935220d34d8855dca57d6e9d2f1e6
https://doi.org/10.24292/01.mf.0318.5

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A conformationally restricted GABA analogue based on octahydro-1H-cyclopenta[b]pyridine scaffold

Autor: Kostiantyn P. Melnykov, Dmitriy M. Volochnyuk, Eduard B. Rusanov, Oleksandr O. Grygorenko, Sergey V. Ryabukhin

Publikováno v: Amino acids. 51(2)

An approach to rel-(4aS,6R,7aR)-octahydro-1H-cyclopenta[b]pyridine-6-carboxylic acid—a bicyclic conformationally restricted γ-aminobutyric acid (GABA) analogue was developed. The eight-step sequence relied on the reaction of 2,3-bis(chloromethyl)p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c461cc8d7cbfa968ecd2fc84e260106
https://pubmed.ncbi.nlm.nih.gov/30288603

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Dissertation/ Thesis

New enantioselective transformations induced by cyclodextrins : applications in the preparation of molecular building blocks of biological interest

Autor: Mansour, Ali Taher

Le but de ce travail était la préparation de dérivés cyclobutaniques du GABA optiquement purs et leur utilisation dans la préparation de γ/α-peptides pouvant adopter une structure tridimensionnelle bien définie. Pour cela, deux stratégies on

Externí odkaz: http://www.theses.fr/2018SACLS186/document

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Nouvelles transformations énantiosélectives dirigées par des cyclodextrines : applications pour la préparation de briques moléculaires d’intérêt biologique

Autor: Mansour, Ali Taher

Publikováno v: Organic chemistry. Université Paris Saclay (COmUE); Université Libanaise, 2018. English. ⟨NNT : 2018SACLS186⟩

This work revolves around the synthesis of ennatiomerically pure cyclobutane derivatives of GABA, and their use in the preparation of hybrid γ/α-peptides that could adopt a well-defined three dimensional secondary structure. In this aim we develope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::8ae179d2fafd47d8fdcb984530282213
https://tel.archives-ouvertes.fr/tel-02343180/file/71412_MANSOUR_2018_archivage.pdf

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GABA promotes survival and axonal regeneration in identifiable descending neurons after spinal cord injury in larval lampreys

Autor: Daniel Romaus-Sanjurjo, Kendra L. Hanslik, Blanca Fernández-López, Antón Barreiro-Iglesias, Jennifer R. Morgan, Rocio Ledo-Garcia, María Celina Rodicio

Publikováno v: Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
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Cell Death and Disease, Vol 9, Iss 6, Pp 1-15 (2018)
Cell Death & Disease

The poor regenerative capacity of descending neurons is one of the main causes of the lack of recovery after spinal cord injury (SCI). Thus, it is of crucial importance to find ways to promote axonal regeneration. In addition, the prevention of retro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3619bc245639ebe0f0d49a47d0608b7c
https://hdl.handle.net/10347/17645

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Dissertation/ Thesis

Síntese de novos heterociclos a partir do ácido levulínico

Autor: Piovesan, Luciana Almeida

Publikováno v: Repositório Institucional da UFSMUniversidade Federal de Santa MariaUFSM.

Conselho Nacional de Desenvolvimento Científico e Tecnológico
The synthesis of new compounds alkyl 3-azolyl propanoate e alkyl 3-azolyl propanoic acid structurally analogues to gamma-aminobutiric acid (GABA) is reported. One more time using th

Externí odkaz: http://repositorio.ufsm.br/handle/1/4233

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