Zobrazeno 1 - 10
of 3 921
pro vyhledávání: '"G2-M DNA damage checkpoint"'
Publikováno v:
The Plant Journal. 109:490-507
Being sessile organisms, plants are ubiquitously exposed to stresses that can affect the DNA replication process or cause DNA damage. To cope with these problems, plants utilize DNA damage response (DDR) pathways, consisting of both highly conserved
Publikováno v:
Environmental Toxicology. 37:224-236
Circular RNA-synaptosome associated protein 47 (circ-SNAP47; Hsa_circ_0016760) is oncogenic in non-small-cell lung cancer (NSCLC); however, its role is undescribed in cis-diamminedichloroplatinum II (DDP) resistance. We attempted to investigate its e
Autor:
Chuanping Yi, Wangsheng Zhao, Hui Luo, Jincheng Zhong, Hongying Wang, Chuanfei Xu, Shixin Wu, TserangDonko Mipam, Xin Cai
Publikováno v:
Functional & Integrative Genomics. 21:665-678
Cattleyaks are the crossbred offspring between cattle and yaks, exhibiting the prominent adaptability to the harsh environment as yaks and much higher growth performances than yaks around Qinghai-Tibet plateau. Unfortunately, cattleyak cannot be effe
Autor:
Damien D’Amours, Maria Teresa Teixeira, Héloïse Coutelier, Jeanne Le Peillet, Zhou Xu, Oana Ilioaia, Marion Hamon
Publikováno v:
Genetics
Genetics, 2022, ⟨10.1093/genetics/iyac171⟩
Genetics, 2022, ⟨10.1093/genetics/iyac171⟩
Telomere dysfunction activates the DNA damage checkpoint to induce a cell cycle arrest. After an extended period of time, however, cells can bypass the arrest and undergo cell division despite the persistence of the initial damage, a process called a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e8d83863fb71a55390edeb5ac4b7af
https://hal.science/hal-03856147
https://hal.science/hal-03856147
Publikováno v:
The FEBS Journal. 288:6035-6051
Upon exposure to genotoxic stress, cells activate DNA damage response (DDR) that coordinates DNA repair with a temporal arrest in the cell cycle progression. DDR is triggered by activation of ataxia telangiectasia mutated/ataxia telangiectasia and Ra
Autor:
Richard G. Gardner, Heather R. Borror, Amanda Bradley, Kaitlyn E Mostoller, Nicole M Marsh, Amber I. Gama
Publikováno v:
Molecular Biology of the Cell. 32:1121-1133
Stress is a ubiquitous part of life that disrupts cellular function and, if unresolved, can irreparably damage essential biomolecules and organelles. All organisms can experience stress in the form of unfavorable environmental conditions including ex
Autor:
David S. Perlin, Erika Shor
Publikováno v:
Curr Genet
How cells respond to DNA damage is key to maintaining genome integrity or facilitating genetic change. In fungi, DNA damage responses have been extensively characterized in the model budding yeast Saccharomyces cerevisiae, which is generally not path
Publikováno v:
The International Journal of Developmental Biology. 65:523-536
The cnidarian Hydra possesses remarkable regenerative capabilities which allow it to regrow lost or damaged body parts in a matter of days. Given that many key regulators of regeneration and development are evolutionarily conserved, Hydra is a valuab
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 6343-6354 (2021)
Cells are constantly challenged by internal or external genotoxic assaults, which may induce a high frequency of DNA lesions, leading to genome instability. Accumulation of damaged DNA is severe or even lethal to cells and can result in abnormal prol
Autor:
KS Lee, Su Hyung Park
Publikováno v:
Experimental & Molecular Medicine
Eukaryotic sliding clamp proliferating cell nuclear antigen (PCNA) plays a critical role as a processivity factor for DNA polymerases and as a binding and acting platform for many proteins. The ring-shaped PCNA homotrimer and the DNA damage checkpoin