Zobrazeno 1 - 10
of 14
pro vyhledávání: '"G2 phase cell cycle checkpoint"'
Autor:
Pinar Sahinturk, Muhittin Aygün, Seyma Aydinlik, Jenaidullah Batur, Ceyda Icsel, Veysel T. Yilmaz
Publikováno v:
European Journal of Medicinal Chemistry. 139:901-916
New silver(I) 5,5-diethylbarbiturate (barb) complexes with a series of bis(diphenylphosphino)alkanes such as 1,1-bis(diphenylphosphino)methane (dppm), 1,2-bis(diphenylphosphino)ethane (dppe), 1,3-bis-(diphenylphosphino)propane (dppp) and 1,4-bis(diph
Autor:
Ala-Eddin Al Moustafa, Dana Elkhalifa, Mohammed H. Qusa, Feras Q. Alali, Farhan S. Cyprian, Abu Bakar Siddique, Ashraf A. Khalil, Khalid A. El Sayed
Publikováno v:
European journal of medicinal chemistry. 187
Great strides have been made in triple negative breast cancer (TNBC) treatment, which represents 20% of total predicted annual US breast cancer (BC) cases. Despite the development of several therapeutics, TNBC patients have poor overall survival rate
Autor:
Beste Yurdacan, Gulsah Cecener, Berrin Tunca, Unal Egeli, Isil Ezgi Eryilmaz, Gamze Guney Eskiler
Usnic acid (UA) is a multifunctional bioactive lichen secondary metabolite with potential anti-cancer properties. Although the promising therapeutic effects of UA have been investigated in different cancer cell lines, the mechanism driving UA-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d2439b7c32adeef4ccc60edbb1ef2e
https://hdl.handle.net/20.500.12619/71938
https://hdl.handle.net/20.500.12619/71938
Autor:
Marina Porcelli, Stefania D'Angelo, Giovanna Cacciapuoti, Daniela Cristina Vuoso, Luigi Mele, Elisa Martino, Nunzia D'Onofrio
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Polyphenols represent the most studied class of nutraceuticals that can be therapeutics for a large spectrum of diseases, including cancer. In this study, we investigated for the first time the antitumor activities of polyphenol extract from Annurca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54cdad4c7d6f141aa8bcd4c84c856d30
http://hdl.handle.net/11591/416330
http://hdl.handle.net/11591/416330
Purpose The purpose of the study was to produce BMN 673 loaded solid lipid nanoparticles (SLNs) to improve its therapeutic index, to minimize toxicity and to overcome homologous recombination (HR)-mediated resistance.MethodsFirstly, BMN 673-SLNs were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460dd571d246ed7869e51ef5b8469901
https://hdl.handle.net/20.500.12619/65574
https://hdl.handle.net/20.500.12619/65574
Autor:
Cédric Coulouarn, Bruno Clément, Gaëlle Angenard, Bruno Laviolle, Grégoire Le Gac, Hélène Beloeil
Publikováno v:
Anesthesia and Analgesia
Anesthesia and Analgesia, Lippincott, Williams & Wilkins, 2017, 125 (5), pp.1600-1609. ⟨10.1213/ANE.0000000000002429⟩
Anesthesia & Analgesia
Anesthesia & Analgesia, 2017, 125 (5), pp.1600-1609. ⟨10.1213/ANE.0000000000002429⟩
Anesthesia and Analgesia, Lippincott, Williams & Wilkins, 2017, 125 (5), pp.1600-1609. ⟨10.1213/ANE.0000000000002429⟩
Anesthesia & Analgesia
Anesthesia & Analgesia, 2017, 125 (5), pp.1600-1609. ⟨10.1213/ANE.0000000000002429⟩
International audience; BACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive cancer with limited therapeutic options. Retrospective studies have shown that the administration of local anesthetics (LAs) during cancer surgery could reduce cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856e6890d0fc324fc78461ccf2e48489
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01637191
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01637191
Autor:
Catherine Eichwald, Selene Glück, Anita F. Meier, Bernd Vogt, Mathias Ackermann, Elisabeth M. Schraner, Francesca Arnoldi, Antonino Buttafuoco
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0179607 (2017)
PLoS ONE, Vol 12, Iss 6, p e0179607 (2017)
In infected cells rotavirus (RV) replicates in viroplasms, cytosolic structures that require a stabilized microtubule (MT) network for their assembly, maintenance of the structure and perinuclear localization. Therefore, we hypothesized that RV could
Publikováno v:
Biochemical Society transactions. 42(5)
Protein kinases C (PKCs) are a family of serine/threonine kinases which act as key regulators in cell cycle progression and differentiation. Studies of the involvement of PKCs in cell proliferation showed that their role is dependent on cell models,
Autor:
Elena Nasonova, S. Luft, Onetsine Arrizabalaga, Sylvia Ritter, Marco Durante, Alexander Helm, Diana Pignalosa
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 760
The risk of radiation exposure during embryonic development is still a major problem in radiotoxicology. In this study we investigated the response of the murine embryonic stem cell (mESC) line D3 to two radiation qualities: sparsely ionizing X-rays
Publikováno v:
ChemMedChem.
Redox chemotherapy: Antiproliferative activities of a series of N-substituted 1,2-dihydroquinolines capable of causing redox imbalance in cancer cells are presented. Detailed studies showed that these derivatives arrest the cell cycle in the G2/M pha