Extending the G1 phase improves the production of lipophilic compounds in yeast by boosting enzyme expression and increasing cell size.

Autor: Hao H; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.; Frontier Research Institute for Synthetic Biology, Tianjin University, Tianjin 300072, China., Yao M; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.; Frontier Research Institute for Synthetic Biology, Tianjin University, Tianjin 300072, China., Wang Y; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.; Frontier Research Institute for Synthetic Biology, Tianjin University, Tianjin 300072, China., Zhang C; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.; Frontier Research Institute for Synthetic Biology, Tianjin University, Tianjin 300072, China., Liu Z; College of Life Science and Technology, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China., Nielsen J; College of Life Science and Technology, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.; Department of Life Sciences, Chalmers University of Technology, Gothenburg SE41296, Sweden.; BioInnovation Institute, Copenhagen DK2200, Denmark., Shi S; College of Life Science and Technology, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China., Xiao W; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.; Frontier Research Institute for Synthetic Biology, Tianjin University, Tianjin 300072, China.; School of Life Sciences, Faculty of Medicine, Tianjin University, Tianjin 300072, China.; Georgia Tech Shenzhen Institute, Tianjin University, Shenzhen 518071, China., Yuan Y; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.; Frontier Research Institute for Synthetic Biology, Tianjin University, Tianjin 300072, China.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Nov 19; Vol. 121 (47), pp. e2413486121. Date of Electronic Publication: 2024 Nov 13.

Methanolic Extract of Cimicifuga foetida Induces G 1 Cell Cycle Arrest and Apoptosis and Inhibits Metastasis of Glioma Cells.

Autor: Chang CH; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80756, Taiwan., Tsai HP; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan., Yen MH; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80756, Taiwan., Lin CJ; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.

Publikováno v: Nutrients [Nutrients] 2024 Sep 26; Vol. 16 (19). Date of Electronic Publication: 2024 Sep 26.

Hydroxychloroquine inhibits the growth of lung cancer cells by inducing G1 cell cycle arrest and apoptosis.

Autor: Fu S; College of Pharmacy, Qiqihar Medical University, Qiqihar, China., Liu L; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, China., Wang Y; Department of Medical Technology, Qiqihar Medical University, Qiqihar, China., Liu W; College of Pharmacy, Qiqihar Medical University, Qiqihar, China., Sun S; Department of Medical Technology, Qiqihar Medical University, Qiqihar, China., Gao XL; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, China., Zhu W; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, China., Yue L; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, China.

Publikováno v: Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2024 Sep; Vol. 37 (5), pp. 981-991.

Autophagic degradation of CDK4 is responsible for G0/G1 cell cycle arrest in NVP-BEZ235-treated neuroblastoma.

Autor: Liu Z; Department of Clinical Laboratory, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.; Department of Oncology, Shanghai ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Wang XY; Department of Blood Transfusion, The Sanmenxia Central Hospital, Sanmenxia, Henan Province, China., Wang HW; Department of Rheumatology and Immunology, Bengbu Third People's Hospital Affiliated to Bengbu Medical College, Bengbu, Anhui, China., Liu SL; Department of Clinical Laboratory, The First Hospital of Changsha City,Changsha, Hunan, China., Zhang C; Department of Geriatrics, Shanghai ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Liu F; Department of Oncology, Shanghai ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Guo Y; Department of Pathology, Yellow River Hospital Attached Henan University of Science and Technology, Sanmenxia, Henan Province, China., Gao FH; Department of Oncology, Shanghai ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Publikováno v: Cancer biology & therapy [Cancer Biol Ther] 2024 Dec 31; Vol. 25 (1), pp. 2385517. Date of Electronic Publication: 2024 Aug 01.

Ruthenium-dihydroartemisinin complex: a promising new compound for colon cancer prevention via G1 cell cycle arrest, apoptotic induction, and adaptive immune regulation.

Autor: Wang CZ; Tang Center for Herbal Medicine Research, and Department of Anesthesia & Critical Care, University of Chicago, 5841 South Maryland Avenue, MC 4028, Chicago, IL, 60637, USA. czwang@dacc.uchicago.edu.; Central Laboratory, The No. 1 Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, 650021, China. czwang@dacc.uchicago.edu., Wan C; Tang Center for Herbal Medicine Research, and Department of Anesthesia & Critical Care, University of Chicago, 5841 South Maryland Avenue, MC 4028, Chicago, IL, 60637, USA.; Central Laboratory, The No. 1 Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, 650021, China., Li CH; Tang Center for Traditional Chinese Medicine Research, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China., Liang GG; Tang Center for Traditional Chinese Medicine Research, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China., Luo Y; Tang Center for Herbal Medicine Research, and Department of Anesthesia & Critical Care, University of Chicago, 5841 South Maryland Avenue, MC 4028, Chicago, IL, 60637, USA., Zhang CF; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China., Zhang QH; School of Chemistry and Chemical Engineering, Chongqing University, Chongqing, 400044, China., Ma Q; Tang Center for Herbal Medicine Research, and Department of Anesthesia & Critical Care, University of Chicago, 5841 South Maryland Avenue, MC 4028, Chicago, IL, 60637, USA., Wang AH; Tang Center for Herbal Medicine Research, and Department of Anesthesia & Critical Care, University of Chicago, 5841 South Maryland Avenue, MC 4028, Chicago, IL, 60637, USA., Lager M; Tang Center for Herbal Medicine Research, and Department of Anesthesia & Critical Care, University of Chicago, 5841 South Maryland Avenue, MC 4028, Chicago, IL, 60637, USA., Jiang TL; Tang Center for Traditional Chinese Medicine Research, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China., Hou L; Program in Cellular and Molecular Medicine, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA., Yuan CS; Tang Center for Herbal Medicine Research, and Department of Anesthesia & Critical Care, University of Chicago, 5841 South Maryland Avenue, MC 4028, Chicago, IL, 60637, USA.; Committee On Clinical Pharmacology and Pharmacogenomics, University of Chicago, Chicago, IL, 60637, USA.

Publikováno v: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2024 May; Vol. 93 (5), pp. 411-425. Date of Electronic Publication: 2024 Jan 09.