Zobrazeno 1 - 10
of 181
pro vyhledávání: '"G0S2"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background Tumour invading muscle in head and neck squamous cell carcinoma (HNSCC) is often associated with destructive growth and poor prognosis. However, the phenotypic functions and pathological mechanisms of muscle-invasive cancer cells
Externí odkaz:
https://doaj.org/article/99a8b6f073c04c618411952768e71114
Autor:
Andrea K. Corbet, Emmanuel Bikorimana, Raya I. Boyd, Doha Shokry, Kelly Kries, Ayush Gupta, Anneliese Paton, Zhengyang Sun, Zeeshan Fazal, Sarah J. Freemantle, Erik R. Nelson, Michael J. Spinella, Ratnakar Singh
Publikováno v:
Translational Oncology, Vol 33, Iss , Pp 101676- (2023)
G0/G1 switch gene 2 (G0S2) is known to inhibit lipolysis by inhibiting adipose triglyceride lipase (ATGL). In this report, we dissect the role of G0S2 in ER+ versus ER- breast cancer. Overexpression of G0S2 in ER- cells increased cell proliferation,
Externí odkaz:
https://doaj.org/article/cbcbc9b7c9dc4ba880141b3cdbbac673
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundPrevious research has shown a tight relationship between the G0/G1 switch gene 2 (G0S2) and metabolic diseases such as non-alcoholic fatty liver disease (NAFLD) and obesity and diabetes, and insulin resistance has been shown as the major ri
Externí odkaz:
https://doaj.org/article/cc87d67e55524aa089d1b7c369e1630d
Autor:
Mayra A. Gonzalez, Idaly M. Olivas, Alfonso E. Bencomo‐Alvarez, Andres J. Rubio, Christian Barreto‐Vargas, Jose L. Lopez, Sara K. Dang, Jonathan P. Solecki, Emily McCall, Gonzalo Astudillo, Vanessa V. Velazquez, Katherine Schenkel, Kelaiah Reffell, Mariah Perkins, Nhu Nguyen, Jehu N. Apaflo, Efren Alvidrez, James E. Young, Joshua J. Lara, Dongqing Yan, Anna Senina, Jonathan Ahmann, Katherine E. Varley, Clinton C. Mason, Christopher A. Eide, Brian J. Druker, Md Nurunnabi, Osvaldo Padilla, Sudip Bajpeyi, Anna M. Eiring
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 12, Pp n/a-n/a (2022)
Abstract Tyrosine kinase inhibitors (TKIs) targeting BCR::ABL1 have turned chronic myeloid leukaemia (CML) from a fatal disease into a manageable condition for most patients. Despite improved survival, targeting drug‐resistant leukaemia stem cells
Externí odkaz:
https://doaj.org/article/0d778c96fbce4f62a37c6a5e642b07ee
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Yinfang Wang, Yanli Hou, Weiwei Zhang, Angel A. Alvarez, Yongrui Bai, Bo Hu, Shi-Yuan Cheng, Kun Yang, Yanxin Li, Haizhong Feng
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Abstract Background Ionizing radiation (IR) therapy is the standard first-line treatment for newly diagnosed patients with glioblastoma (GBM), the most common and malignant primary brain tumor. However, the effects of IR are limited due to the aberra
Externí odkaz:
https://doaj.org/article/81c67ce5a8be41efba0d8c2f015632df
Publikováno v:
Animals, Vol 12, Iss 7, p 916 (2022)
Gene single nucleotide polymorphisms can be used as auxiliary markers in molecular breeding and are an effective method to improve production performance. G0S2 is a key gene involved in regulating fat metabolism, but little research has been conducte
Externí odkaz:
https://doaj.org/article/2e84bbde3eb1484b8532669de17861b5
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Naoya Matsunaga, Eriko Ikeda, Keisuke Kakimoto, Miyako Watanabe, Naoya Shindo, Akito Tsuruta, Hisako Ikeyama, Kengo Hamamura, Kazuhiro Higashi, Tomohiro Yamashita, Hideaki Kondo, Yuya Yoshida, Masaki Matsuda, Takashi Ogino, Kazutaka Tokushige, Kazufumi Itcho, Yoko Furuichi, Takaharu Nakao, Kaori Yasuda, Atsushi Doi, Toshiaki Amamoto, Hironori Aramaki, Makoto Tsuda, Kazuhide Inoue, Akio Ojida, Satoru Koyanagi, Shigehiro Ohdo
Publikováno v:
EBioMedicine, Vol 13, Iss C, Pp 262-273 (2016)
Chronic kidney disease (CKD) is a global health problem, and novel therapies to treat CKD are urgently needed. Here, we show that inhibition of G0/G1 switch 2 (G0s2) ameliorates renal inflammation in a mouse model of CKD. Renal expression of chemokin
Externí odkaz:
https://doaj.org/article/78a7228c8a9c43ea90380dcc86ba6101
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.