Zobrazeno 1 - 10
of 228
pro vyhledávání: '"G.P. Raaphorst"'
Publikováno v:
Journal of Thermal Biology. 30:478-484
Earlier data showed that cultured cells are more hyperthermia sensitive in S phase of the cell cycle. In part this sensitivity may be related to the disruption of DNA repair/processing activity in S phase. It is well known that many components of DNA
Publikováno v:
Journal of Thermal Biology. 25:305-311
Long duration mild hyperthermia (LDMH) has been shown to be an effective radiosensitizer when combined with low dose rate irradiation and pulsed low dose rate irradiation. These protocols are being investigated to determine if these effects can be re
Publikováno v:
Cancer/Radiothérapie. 3:318-324
Resume Objectif de l'etude Etudier retrospectivement la radiosensibilite in vitro de fibroblastes derives de deux groupes de patients traites par irradiation, ayant ou non des complications. Patients et methodes Sept patients traites par irradiation
Publikováno v:
Radiation Oncology Investigations. 7:153-157
Human glioma cells were exposed to stepwise increasing concentrations of cisplatin and given a final, acute, high concentration treatment of cisplatin. From the surviving cells, eight cisplatin resistant clones were selected. These clones demonstrate
Publikováno v:
Radiation Oncology Investigations. 5:1-7
Two human melanoma cell lines (one radiosensitive, HT144 and one radioresistant, SK Mel-3) and one normal human fibroblast (AG1522) were evaluated for thermal radiosensitization and the thermal enhancement ratios (TERs) were calculated. These were co
Publikováno v:
Journal of Thermal Biology. 21:239-244
Human glioma cells were studied to evaluate the effect long duration mild hyperthermia (LDMH), (up to 48 h) had on radiosensitization following heating and this was compared to LDMH given concurrently during low dose-rate irradiation. LDMH did not in
Publikováno v:
Gynecologic Oncology. 61:116-121
We report a case of severe chronic normal tissue injury following conventional irradiation in a 33-year-old patient with a strong family history of cancer. Her cultured fibroblasts exhibited a response to low-dose-rate irradiation similar to fibrobla
Publikováno v:
International Journal of Radiation Biology. 66:49-57
We investigated the ability of camptothecin (CPT), an inhibitor of topoisomerase (topo) I, and etoposide (VP-16), an inhibitor of topo II, to potentiate X-radiation response and to inhibit the repair of potentially lethal damage (PLDR) and sublethal
Publikováno v:
Melanoma Research. 2:63-70
Comparison of the heat sensitivity and radiosensitivity of four human melanoma cell lines in culture revealed a large variation in sensitivity amongst the four cell lines. Three of the four cell lines had large shoulders on the survival curves when e
Autor:
G.P. Raaphorst, E.I. Azzam
Publikováno v:
Journal of Thermal Biology. 17:19-24
1. 1.|Aphidicolin and β ara A, which are known inhibitors of polymerases α and β, can be used to evaluate the role of polymerases in recovery of radiation damage. 2. 2.|In this study the effect of these compounds was tested on recovery of potentia