Zobrazeno 1 - 10
of 39
pro vyhledávání: '"G.M. Simone"'
Autor:
Danila De Vito, Marco Tatullo, Salvatore Scacco, Massimo Marrelli, Gianfranco Irlandese, Franco Tarullo, Andrea Ballini, Tiziana Cocco, G.M. Simone, Luigi Santacroce
Publikováno v:
Scientific Reports
There is increasing interest in identifying natural bioactive compounds that can improve mitochondrial functionality and regulate apoptosis. The brewery industry generates wastewater that could yield a natural extract containing bioactive phenolic co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e834753eccbcb9af15b6ea3e704082
https://doi.org/10.1038/srep36042
https://doi.org/10.1038/srep36042
Autor:
Angelo Paradiso, Amalia Azzariti, Massimo Zucchetti, Maurizio D'Incalci, G.M. Simone, Nicola Antonio Colabufo, Anna Elisa Quatrale, Letizia Porcelli, Roberto Perrone, Jianming Xu, Francesco Berardi
Publikováno v:
Cancer Chemotherapy and Pharmacology. 65:335-346
Although multidrug resistance (MDR) proteins are known to play a role in drug resistance and modification pharmacodynamic characteristics of certain conventional chemotherapeutics, information about their interactions with tyrosine kinase inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1561872d44c80b1360c13916f8bf8e
https://doi.org/10.1007/s00280-009-1039-0
https://doi.org/10.1007/s00280-009-1039-0
Autor:
Stefania Tommasi, Orazio Palumbo, Antonio Logroscino, Daniela Petriella, S. De Summa, Massimo Carella, G.M. Simone, Francesco Alfredo Zito, Annamaria Catino, Rosanna Lacalamita, Domenico Galetta
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 37(4)
In NSCLC, the altered expression of some miRNAs in primary tumor tissues has been correlated with diagnosis and prognosis, while the role of circulating miRNAs as cancer biomarkers is currently emerging. MiRNA expression profile through miRNA Affymet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414e4dccba854480441481f30a6f0093
https://pubmed.ncbi.nlm.nih.gov/26566629
https://pubmed.ncbi.nlm.nih.gov/26566629
Autor:
Bernardo Amadeo Leone, Francesco Schittulli, M. De Lena, Anita Mangia, G. Naccarato, A. Paradiso, Nicola Silvestris, Carlos Teodoro Vallejo, G.M. Simone, Girolamo Ranieri, G. Bevilacqua
Publikováno v:
Clinical and Experimental Medicine. 1:127-132
In the present study, the primary tumor neoangiogenesis characteristics of 81 stage IV previously untreated breast cancers with synchronous metastasis to different distant sites (10 patients with soft tissue metastases, 31 with bone metastases, and 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c19697f7916662bcc3184f710899ae6
https://doi.org/10.1007/s10238-001-8023-2
https://doi.org/10.1007/s10238-001-8023-2
Autor:
Aurora Costa, Bernardo Amadeo Leone, J. A. Lacava, M. De Lena, A. Paradiso, Carlos Teodoro Vallejo, G.M. Simone, S Dellapasqua, Maria Grazia Daidone
Publikováno v:
British Journal of Cancer
The clinical relevance of bax and bcl-2 protein expression has been investigated in 84 patients with recurrent or metastatic colorectal cancer submitted to a chemotherapy regimen including methotrexate and fluorouracil/leucovorin. Cytoplasmic immunos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7df75df9ba1cf982e94d6066de9b62
https://doi.org/10.1054/bjoc.2000.1658
https://doi.org/10.1054/bjoc.2000.1658
Autor:
Carlos Teodoro Vallejo, S. Petroni, P. G. Johnston, Bernardo Amadeo Leone, G.M. Simone, M. De Lena, J. A. Lacava, Carmen J. Allegra, M Machiavelli, A Romero, Angelo Paradiso
Publikováno v:
British Journal of Cancer
The purpose of this work was to analyse the ability of p53 and thymidilate synthase (TS) primary tumour expression to retrospectively predict clinical response to chemotherapy and long-term prognosis in patients with advanced colorectal cancers homog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae00793049aa8000a06fb1eb43518652
https://doi.org/10.1054/bjoc.1999.0964
https://doi.org/10.1054/bjoc.1999.0964
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 22
BRCA1- and BRCA2-deficient cells display genomic instability due to impaired DNA repair and may subsequently be predisposed to malignant transformation. Cancers arising in BRCA1 gene mutation carriers differ substantially from sporadic breast cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898fc6f3bdc2d4e94ca84778055d46d7
https://pubmed.ncbi.nlm.nih.gov/21285147
https://pubmed.ncbi.nlm.nih.gov/21285147
Autor:
Antonio Mazzocca, G. Grazia, Antonella Daniele, G. Caldarola-Gadaleta, F. Giuliani, A. Bellizzi, G.M. Simone, E. Savino, Cosmo Damiano Gadaleta, Rosa Divella, Michele Quaranta, Ivan Lolli
Publikováno v:
European Journal of Cancer. 50:e18-e19
Purpose Colon carcinoma is a malignant tumor showing a marked preference to metastasize to distant organs. The presence of circulating tumor cells (CTCs) in the peripheral blood is a prerequisite for the formation of distant metastases. However, whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0a80e6c37d6eaf81d95a34e4f7ef6c0
https://doi.org/10.1016/j.ejca.2014.03.080
https://doi.org/10.1016/j.ejca.2014.03.080
Autor:
Rosanna Lacalamita, Massimo Tommasino, Amalia Azzariti, Brunella Pilato, A. Paradiso, D. Conti, G.M. Simone, Letizia Porcelli, Sinto Sebastian, Rosita Accardi, Stefania Tommasi
Publikováno v:
Scopus-Elsevier
Recently improved understanding of the pathogenesis of human head and neck squamous cell carcinoma (HNSCC) has led to the development of new, molecular-based therapeutic strategies, one of the more promising is the utilisation of tyrosine kinase (TK)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71f7528a599323d38c45a39f4117a99
https://pubmed.ncbi.nlm.nih.gov/18506376
https://pubmed.ncbi.nlm.nih.gov/18506376
Autor:
Nicola Antonio Colabufo, Carmela Inglese, Mauro Niso, Francesco Berardi, Mariangela Cantore, Angelo Paradiso, Roberto Perrone, G.M. Simone, Marialessandra Contino, Amalia Azzariti, Maria Grazia Perrone
Publikováno v:
Bioorganicmedicinal chemistry. 16(7)
Starting from lead compound 1 (EC50 = 1.64 μM), its non-basic nucleus has been conformationally restricted by 4-biphenyl and 2-naphthyl moieties. In each series we investigated if the presence of H-bond donor or acceptor substituents, the basicity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3171dd95672650d34611b3662728abcc
https://pubmed.ncbi.nlm.nih.gov/18276145
https://pubmed.ncbi.nlm.nih.gov/18276145