Zobrazeno 1 - 10
of 560
pro vyhledávání: '"G.M. Roberts"'
Autor:
Daniel G.M. Roberts, Qi Gao, Victor W. Rosso, Jun Qiu, Jacob M. Janey, Joshua A. Selekman, Joseph Nolfo
Publikováno v:
Organic Process Research & Development. 20:70-75
A critical component of defining the feasible design space for an active pharmaceutical ingredient (API) crystallization is isolating the preferred polymorph or crystal form of the compound, which defines many of the compound’s performance-defining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::439dbf02112a74e0d54938dd7de2e914
https://doi.org/10.1021/acs.oprd.5b00346
https://doi.org/10.1021/acs.oprd.5b00346
Publikováno v:
Crystal Growth & Design. 16:12-24
A novel pure component approach using HyperDSC for the relative stability determination was reported in 2012 (Hsieh et al. Cryst. Growth Des. 2012, 12, 5481). The accuracy of this approach depends upon the accurate physical properties of the amorphou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6991e7a7007b0c419917330212afd95
https://doi.org/10.1021/acs.cgd.5b00443
https://doi.org/10.1021/acs.cgd.5b00443
Autor:
Jun Li, Qi Gao, Deniz Erdemir, Chiajen Lai, Ming Huang, Alicia Ng, Daniel G.M. Roberts, Jun Huang, Daniel S. Hsieh, David K. Leahy
Publikováno v:
Crystal Growth & Design. 12:5481-5490
The determination of the relative stability of multipolymorph compounds is very important to chemical processes and product development. Two thermodynamic methods are used in this study: a eutectic method and a pure component method. The eutectic met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b70db46fd6b7ae65886f4709a1de4204
https://doi.org/10.1021/cg3010568
https://doi.org/10.1021/cg3010568
Autor:
Paraschiv, Elena-Anca1,2 (AUTHOR) cristian.petrache@ici.ro, Băjenaru, Lidia1,3 (AUTHOR) elena.paraschiv@ici.ro, Petrache, Cristian1 (AUTHOR) dragos.nicolau@ici.ro, Bica, Ovidiu1 (AUTHOR), Nicolau, Dragoș-Nicolae1 (AUTHOR)
Publikováno v:
Future Internet. Nov2024, Vol. 16 Issue 11, p424. 21p.
Autor:
Kim, Jaewhan1 (AUTHOR) jaewhan.kim@utah.edu, Duru, Emeka Elvis2 (AUTHOR) elvis.duru@utah.edu, Weir, Peter3 (AUTHOR) peter.weir@utah.edu, Lee, Sanghoon4 (AUTHOR) sanghoonlee@hnu.kr
Publikováno v:
COVID. Nov2024, Vol. 4 Issue 11, p1719-1730. 12p.
Autor:
van den Brink, Luna1,2,3 (AUTHOR) l.vandenbrink@amsterdamumc.nl, Debelle, Tess2 (AUTHOR), Gietelink, Lieke4 (AUTHOR), Graafland, Niels5 (AUTHOR), Ruiter, Annebeth6 (AUTHOR), Bex, Axel5,7 (AUTHOR), Beerlage, Harrie P.1 (AUTHOR), van Moorselaar, R. Jeroen A.2 (AUTHOR), Lagerveld, Brunolf6 (AUTHOR), Zondervan, Patricia1 (AUTHOR)
Publikováno v:
Cancers. Oct2024, Vol. 16 Issue 20, p3518. 8p.
Autor:
Daniel G.M. Roberts, Wan F. Lau, Wen-Ching Han, Martin L. Ogletree, William A. Schumacher, Tammy C. Wang, James Lin, Edwin J. Iwanowicz, S. David Kimball, Steven M. Seiler
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:3183-3186
A series of retro-binding inhibitors of human α-thrombin was prepared to elucidate structure–activity relationships (SAR) and optimize in vivo performance. Compounds 9 and 11, orally active inhibitors of thrombin catalytic activity, were identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8346fdc4173a6da63c59cb90b9947c4
https://doi.org/10.1016/s0960-894x(02)00651-0
https://doi.org/10.1016/s0960-894x(02)00651-0
Autor:
Daniel G.M. Roberts, Mark Lindrud, Sarah J. Nicholson, Richard L. Schild, Daniel S. Hsieh, Hongfei Yue, John F. Gamble
Publikováno v:
Pharmaceutical research. 32(5)
To understand the mechanisms of secondary drying of spray-dried dispersion (SDD) drug product and establish a model to describe the fate of organic solvents in such a product. The experimental approach includes characterization of the SDD particles,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d92b6a91529e61e7174e3d7938711cd
https://pubmed.ncbi.nlm.nih.gov/25515491
https://pubmed.ncbi.nlm.nih.gov/25515491
Publikováno v:
Archaeology in Oceania. 34:25-30
A lead weight was recovered between 2.2 and 2.4 m depth in stranded beach sands at the souther end of Fraser Island. Its isotope values indicate a close affinity with lead from mines in France. Pumice found with the lead occurs elsewhere at sites dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcedbd9ed956a76d115cb5bbb49fd76f
https://doi.org/10.1002/j.1834-4453.1999.tb00423.x
https://doi.org/10.1002/j.1834-4453.1999.tb00423.x