Zobrazeno 1 - 10
of 123
pro vyhledávání: '"G.M. Lees"'
Publikováno v:
The Journal of Comparative Neurology. 410:515-530
Region-specific patterns of nerves with immunoreactivity to neuropeptide Y (NPY) have been described previously in the submucous plexus of guinea pig large intestine. Because these may have functional significance, the possibility of similar, charact
Publikováno v:
British Journal of Pharmacology. 122:330-334
1 The effect of cannabinoid receptor agonists was studied in guinea-pig myenteric neurones in vitro by use of conventional intracellular recording techniques. 2 Exposure of myenteric neurones of the S-cell type to the cannabinoid receptor agonists WI
Publikováno v:
The Anatomical Record. 247:261-270
Background: Although guinea-pig tracheal preparations are used as models of asthma, the morphological and electrophysiological characteristics of its associated ganglion neurones (paratracheal neu- rones) have not been characterized. Methods:Intracel
Autor:
A.D. Corbett, G.M. Lees
Publikováno v:
British Journal of Pharmacology. 120:107-115
1. Since intermittent ischaemia may play an important role in the aetiology of Inflammatory Bowel Disease, particularly Crohn's Disease, a pharmacological model of neuronal ischaemia was applied to guinea-pig isolated intestinal preparations to mimic
Autor:
G.M. Lees, Kirsteen N. Browning
Publikováno v:
Neuroscience. 73:1029-1047
Conventional intracellular electrophysiological recordings were made from 502 myenteric neurons of the rat descending colon. Myenteric neurons could be classified into three groups on the basis of distinct electrophysiological properties. The first g
Autor:
G.M. Lees, Shauna M.C. Cunningham
Publikováno v:
Journal of the Autonomic Nervous System. 55:135-145
Since information about possible regional differences in the innervation of the guinea-pig large intestine is incomplete, a comparative study was made of the occurrence of neurones and nerve fibres of the submucosa showing immunoreactivity (IR) to ne
Publikováno v:
British Journal of Pharmacology. 113:883-888
1. The subtype of neuropeptide Y receptor mediating the selective inhibition of the slow inhibitory postsynaptic potential (i.p.s.p.) of submucous neurones in guinea-pig caecum was investigated by use of conventional intracellular electrophysiologica
Autor:
G.M. Lees, Kirsteen N. Browning
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 12(1)
Intracellular recordings were made from myenteric neurones of the guinea-pig descending colon. Neuropeptide Y (NPY) and related pancreatic polypeptides were applied by superfusion and the effects upon the amplitude of fast excitatory synaptic potenti
Publikováno v:
Neuroscience letters. 227(3)
Effects of neuropeptide Y (NPY) on submucosal neurons of the guinea-pig descending colon were investigated electrophysiologically by means of intracellular electrophysiological recordings. NPY (100 nM) induced a marked and prolonged hyperpolarization