Zobrazeno 1 - 10
of 103
pro vyhledávání: '"G.M. Eccleston"'
Publikováno v:
Pharmaceutical Development and Technology. 19:417-429
The aim of this work is to develop, optimize and characterize cold process emulsions that are stable at acidic pH. The main surfactant was selected according to the hydrophilic lipophilic balance (HLB) concept and surface tension, whereas polymers we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30227c52b3f6df1af1722e1bc2ffde8
https://doi.org/10.3109/10837450.2013.788516
https://doi.org/10.3109/10837450.2013.788516
Publikováno v:
Archives of Pharmacal Research. 35:579-593
Synthetic membranes are composed of thin sheets of polymeric macromolecules that can control the passage of components through them. Generally, synthetic membranes used in drug diffusion studies have one of two functions: skin simulation or quality c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68fb0152ff68cd1b18ce3658f1e397e
https://doi.org/10.1007/s12272-012-0401-7
https://doi.org/10.1007/s12272-012-0401-7
Autor:
Anthony D. Auffret, Howard N.E. Stevens, G.M. Eccleston, Joshua S. Boateng, Kerr H. Matthews, Mike J. Humphrey
Publikováno v:
Drug Development and Industrial Pharmacy. 38:47-54
Drug release characteristics of freeze-dried wafers and solvent-cast films prepared from sodium carboxymethylcellulose have been investigated and compared. In vitro drug dissolution studies were performed using an exchange cell and drug release was m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab5fba6034e3ceede0768612399e380
https://doi.org/10.3109/03639045.2011.590496
https://doi.org/10.3109/03639045.2011.590496
Publikováno v:
International Journal of Pharmaceutics. 411:121-127
Lipogels were prepared by dispersing mixed (60:40 C(16)-C(18)) and pure (C(18)) homologue magnesium stearate (MgSt) in liquid paraffin, using three methods of preparation, i.e. addition of water at 95 °C during cooling cycle (method 1), homogenisati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ed17525fa30062d7d04417a02b65bc
https://doi.org/10.1016/j.ijpharm.2011.03.052
https://doi.org/10.1016/j.ijpharm.2011.03.052
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 2, Iss 2, Pp 209-223 (2010)
Pharmaceutics; Volume 2; Issue 2; Pages: 209-223
Pharmaceutics, Vol 2, Iss 2, Pp 209-223 (2010)
Pharmaceutics; Volume 2; Issue 2; Pages: 209-223
Synthetic membranes used in Franz diffusion cells for topical formulation quality assessment should provide least resistance to drug diffusion. In this study, the diffusion rates of ibuprofen across thirteen membranes were determined using Franz diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b96a06d30144f818aef047dc895d60
http://europepmc.org/articles/PMC3986717
http://europepmc.org/articles/PMC3986717
Autor:
Howard N.E. Stevens, Mike J. Humphrey, Joshua S. Boateng, Anthony D. Auffret, G.M. Eccleston, Kerr H. Matthews
Publikováno v:
International Journal of Pharmaceutics. 378:66-72
Drug dissolution and release characteristics from freeze-dried wafers and solvent-cast films prepared from sodium carboxymethylcellulose (CMC) have been investigated to determine the mechanisms of drug release from the two systems. The formulations w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c10f61f3a93da3998b0b98f6295757
https://doi.org/10.1016/j.ijpharm.2009.05.038
https://doi.org/10.1016/j.ijpharm.2009.05.038
Autor:
G.M. Eccleston, Anthony D. Auffret, Howard N.E. Stevens, Michael John Humphrey, Kerr H. Matthews, Joshua S. Boateng
Publikováno v:
Drug Development and Industrial Pharmacy. 35:986-996
Solvent-cast films from three polymers, carboxymethylcellulose (CMC), sodium alginate (SA), and xanthan gum, were prepared by drying the polymeric gels in air. Three methods, (a) passive hydration, (b) vortex hydration with heating, and (c) cold hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708b6d9ca12ed45ab4ba2a473a34c42b
https://doi.org/10.1080/03639040902744704
https://doi.org/10.1080/03639040902744704
Publikováno v:
International Journal of Pharmaceutics. 358:144-150
The aim of the present study was to use the in vitro human skin sandwich system in order to quantify the influence of formulation variables on intrafollicular hydrocortisone permeation. The investigated variables were the pH and the viscosity of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2913efaaba6d24421de605fc909ee9af
https://doi.org/10.1016/j.ijpharm.2008.02.030
https://doi.org/10.1016/j.ijpharm.2008.02.030
Publikováno v:
Journal of Pharmacy and Pharmacology. 60:145-151
It is already well-established that the general permeability properties of porcine skin are close to those of human skin. However, very little is known with respect to drug absorption into hair follicles and the similarities if any between the two ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b28aca650097655426f25549190e13c
https://doi.org/10.1211/jpp.60.2.0002
https://doi.org/10.1211/jpp.60.2.0002
Publikováno v:
International Journal of Pharmaceutics. 336:140-147
Over recent years, there has been growing evidence that the permeability coefficient variability describing any specific transdermal drug delivery system is not always normally distributed. However, since different researchers have used different tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef5bd85a6558d7e0452eb712449a9b9
https://doi.org/10.1016/j.ijpharm.2006.11.049
https://doi.org/10.1016/j.ijpharm.2006.11.049