Toxicokinetics: Biotransformation of Toxicants

Autor: G.L. Kedderis

Virtually all chemicals that are ingested by animals undergo some chemical change, or biotransformation. The biotransformation of chemicals generally leads to the formation of more polar metabolites that are more readily excreted. There are two types

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0999b77747536940f4b037893409daca
https://doi.org/10.1016/b978-0-12-801238-3.01888-2

The Use of Biokinetics and in Vitro Methods in Toxicological Risk Evaluation

Autor: J. De Jongh, J.M. Frazier, Michael Gülden, Christoph A. Reinhardt, Bas J. Blaauboer, G.L. Kedderis, André Guillouzo, K. Groen, J. B. Houston, G. Johanson, A.M. Hissink, C.T.A. Evelo, M.K. Bayliss, J.J.M. van de Sandt, G. Semino, José V. Castell

Publikováno v: Alternatives to Laboratory Animals. 24:473-497

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33262c884b2bbc67fd103570b744893f
https://doi.org/10.1177/026119299602400408

Biotransformation of Toxicants

Autor: G.L. Kedderis

Virtually all chemicals that are ingested by animals undergo some chemical change or biotransformation. The biotransformation of chemicals generally leads to the formation of more polar metabolites that are more readily excreted. There are two types

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cff3aa4c90cf770b6b9be60f54b1d41
https://doi.org/10.1016/b978-0-08-046884-6.00107-x

N-Demethylation reactions catalyzed by chloroperoxidase

Autor: Dennis R. Koop, P F Hollenberg, G.L. Kedderis

Publikováno v: Journal of Biological Chemistry. 255:10174-10182

The peroxidase-supported N-demethylations catalyzed by chloroperoxidase, a heme protein isolated from Caldariomyces fumago, have been investigated as models for cytochrome P-450-catalyzed N-dealkylations. The turnover number for the ethyl hydrogen pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff5d08bf1d655bbef66733f6f305f7fb
https://doi.org/10.1016/s0021-9258(19)70444-x

SENIOR AUTHORS FOR VOLUMES I AND II

Autor: A.A. Akhrem, L.M. Alexander, A.P. Alvares, B.N. Ames, T. Aralso, A.I. Archakov, E Arinç, R.N. Armstrong, M.J. Arnaud, E. Bachmann, L. Balk, L.M. Ball, J. Baron, L.S. Baskin, N. Beaty, P.M. Belanger, G.D. Bellward, P. Bentley, F.E. Beyhl, R.C. Blake, H. Bonkowsky, A.R. Boobis, B. Bösterling, G.S. Boyd, E. Bresnick, J.W. Bridges, J.A. Bumpus, C. Chen, Y.L. Chlang, A.K. Cho, S.K. Clinton, G. Cohen, A.H. Conney, M.W. Coomes, M.J. Coon, M.A. Correia, C.J. Coscla, P.M. Dansette, J.H. Dees, M. Delaforge, F.A. de la Iglesia, T.R. Devereux, R.N. Dubois, H.B. Dunford, P.H. Duquette, F. Durst, R.E. Ebel, E. Elsenstadt, L. Ernster, R.W. Estabrook, W.E. Fahl, G.C. Farrell, G. Feuer, R. Feyereisen, M.R. Franklin, R.B. Franklin, J.S. French, T.G. Geary, H.V. Gelboin, G.G. Gibson, J.R. Gillette, H.R. Glatt, I.B. Glowinski, D.M. Goldberg, J.W. Gorrod, E.M. Gozukara, H. Graf, C.J. Grandjean, B.W. Griffin, J.T. Groves, F.P. Guengerich, I.C. Gunsalus, J.-Å. Gustafsson, J.R. Halpert, B.D. Hammock, O. Hankinson, O. Hänninen, R.P. Hanzlik, O. Hayaishi, C. Heidelberger, G. Heinemeyer, E. Hietanen, A.G. Hildebrandt, R.N. Hines, M.J. Hintz, P. Hlavica, E. Hodgson, J. Högberg, J.L. Holtzman, J.P. Horwitz, L. Hulett, D.E. Hultquist, R.M. Hyslop, K. Ichlhara, Y. Ichlkawa, M. Ingeiman-Sundberg, T. lyanagl, J. Jansson, E.H. Jeffery, D.M. Jerina, B. Jernström, E.F. Johnson, T. Kamataki, L.S. Kaminsky, J. Kapituinik, F.C. Kauffman, J.C. Kawalek, S. Kawano, G.L. Kedderis, S.R. Keyes, T. Kimura, D.R. Koop, D. Kupfer, B.N. La Du, J.D. Lambeth, F.C.P. Law, M.C. Lechner, S.S. Lee, W. Legrum, W. Lenk, W. Levin, C.S. Leiber, S.L. Longacre, I.S. Longmulr, A.Y.H. Lu, P. Lundberg, V. Luu-The, M.G. Macdonald, P.N. Magee, G.J. Mannering, B. Mannervlk, B.S.S. Masters, T. Matsushlma, D.R. Mattison, P. Maurel, G.D. McCoy, U.A. Meyer, J.J. Mieyal, G.T. Miwa, P. Moldèus, J. Montelius, A. Morello, R. Morgenstern, M.J. Murphy, R.I. Murray, A. Nadezhdin, S. Narasimhulu, R.A. Neal, D.W. Nebert, M. Neglshi, S. Nigam, R.L. Norman, R.F. Novak, P.J. O'Brien, F. Oesch, R.T. Okita, K. Okuda, C.J. Omiecinski, T. Omura, D.D. Oprian, N.R. Orme-Johnson, S. Orrenius, P.R. Ortiz de Montellano, Y. Osawa, G. Padmanaban, M.W. Pariza, S.S. Pawar, F.J. Peterson, J.A. Peterson, R.M. Philpot, J.L. Plummer, L.R. Pohl, R.J. Pohl, C.F. Polnaszek, G. Powis, R.A. Prough, A.D. Rahimtula, D.J. Reed, L.A. Reinke, S.A. Rice, I. Roots, K. Ruckpaul, H.H. Ruf, D.E. Ryan, J. Rydström, S. Safe, R. Sato, J.B. Schenkman, J. Seldegård, I.R. Senciall, H.G. Shertzer, Z.H. Siddik, P. Sinclair, S.R. Slaughter, S.G. Sligar, B.R. Smith, S.J. Stohs, H.W. Strobel, G.D. Sweeney, R. Talcott, H. Tanlguchl, P.E. Thomas, H. Thor, S.S. Thorgeirsson, R.G. Thurman, R. Toftgård, A. Tunek, V. Ullrich, T.A. van der Hoeven, M.E. van Liar, K.P. Vatsls, J.L. Vermilion, M. Vore, C. Welborn, J. Werringloer, S.B. West, R.A. White, R.E. White, R.A. Wiley, E.D. Wills, C.R. Wolf, T. Yamano, C.S. Yang, S.K. Yang, Y. Yasukochi, K.T. Yasunobu, A. Yawetz, Y. Yoshlda, A. Yuasa, V.G. Zannoni, D.M. Ziegler

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ddc7598241b7e79630af1716406a88d
https://doi.org/10.1016/b978-0-12-187701-9.50003-6