Zobrazeno 1 - 9
of 9
pro vyhledávání: '"G.Kenneth Scott"'
Publikováno v:
Bioorganic & Medicinal Chemistry. 7:1953-1964
A series of analogues of, and potential pro-drugs derived from, the potent antibacterial diterpene totarol (1) Download : Download high-res image (85KB) Download : Download full-size image 1 . were synthesized in order to elucidate the minimum struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d813f1b67dba44dac22427cfa967a26c
https://doi.org/10.1016/s0968-0896(99)00162-5
https://doi.org/10.1016/s0968-0896(99)00162-5
Publikováno v:
Cell Biology International. 17:317-324
The possibility that a growth-related proteinase may act by degrading a negative growth regulatory protein has been investigated. Proteinase inhibitors which inhibit the enzyme also enhance the accumulation of the growth regulator by human fibroblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87e425a2357c04e39695427cf321052
https://doi.org/10.1006/cbir.1993.1067
https://doi.org/10.1006/cbir.1993.1067
Autor:
G.Kenneth Scott, JK Perry
Publikováno v:
Bioscience Reports. 10:469-472
Hydrolysis of p-nitrophenyl guanidinobenzoate is characteristic of a tumour cell surface proteinase. We found this activity in three transformed or tumour cell lines, but not in two normal fibroblast strains. Immunochemical inhibition of plasminogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfce1fb1ce5de4c59acc4216d2f80fdb
https://doi.org/10.1007/bf01152294
https://doi.org/10.1007/bf01152294
Publikováno v:
Biochimica et biophysica acta. 1221(2)
Several reports have indicated that proteinase inhibitors can act as both stimulators and inhibitors of the growth of cultured cells. To confirm and extend these reports, we have purified the trypsin inhibitor from human urine (UTI). We have demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38017b21e8666283b1f1b6d122ca32c9
https://pubmed.ncbi.nlm.nih.gov/8148391
https://pubmed.ncbi.nlm.nih.gov/8148391
Autor:
G.Kenneth Scott
Publikováno v:
Comparative biochemistry and physiology. B, Comparative biochemistry. 103(4)
1. 1. Three distinct lines of evidence indicate that proteinases are involved in the growth of cultured animal cells. 2. 2. Endogenous growth-related proteinases have been identified, and exogenous proteinases can also stimulate cell proliferation, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dda3f61aebbc66ff64675c781fd4d27
https://pubmed.ncbi.nlm.nih.gov/1478061
https://pubmed.ncbi.nlm.nih.gov/1478061
Autor:
G.Kenneth Scott
Publikováno v:
International Journal of Biochemistry. 20:817-822
1. 1. Inhibition of a human fibroblast cell-surface proteinase with α-1-antitrypsin also inhibited cell proliferation, confirming earlier observations. 2. 2. Although a similar proteinase inhibition could be observed with human tumour cells, the gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84068b5988e9d4facbe119c12465f295
https://doi.org/10.1016/0020-711x(88)90070-5
https://doi.org/10.1016/0020-711x(88)90070-5
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1010:160-165
Previous experiments have shown that cultured human fibroblasts possess a cell-surface proteinase (the growth-related proteinase; GRP) which is essential to cell proliferation. In the present work, proteinase inhibition in defined and complex serum-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c11ea59e9f95cf3ecba77587692a0c
https://doi.org/10.1016/0167-4889(89)90156-0
https://doi.org/10.1016/0167-4889(89)90156-0
Autor:
G.Kenneth Scott
Publikováno v:
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 87:1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622b21cada783a576c9734c3ab40a50d
https://doi.org/10.1016/0305-0491(87)90462-7
https://doi.org/10.1016/0305-0491(87)90462-7
Autor:
G.Kenneth Scott
Publikováno v:
British journal of haematology. 35(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63d5b92f3c43a01ee6c9b26f5c0261a
https://pubmed.ncbi.nlm.nih.gov/857862
https://pubmed.ncbi.nlm.nih.gov/857862