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pro vyhledávání: '"G.K. Oriji"'
Autor:
G.K. Oriji
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 68:233-238
Chronic treatment with cyclosporine A (CsA), a potent immunosuppressive agent, is associated with the development of arterial hypertension. The effect of CsA on vascular responses was determined in Sprague-Dawley rats and rat aortic rings. Male rats
Autor:
G.K. Oriji
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA). 63:343-349
Adenosine acts as a cardioprotective agent by producing coronary vasodilation, decreasing heart rate and by antagonizing the cardiostimulatory effect of catecholamines; adenosine also exerts a direct negative inotropic effect. Myocardial ischemia is
Autor:
G.K. Oriji
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA). 62:233-237
Angiotensin II (Ang II) has been shown to regulate growth in smooth muscle cells. Protein kinase C (PKC), which mediates Ang II action, has been implicated in myocardial cell hypertrophy. Acute pressure overload in the left ventricles has been demons
Autor:
G.K. Oriji
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA). 60:263-268
Endothelin (ET) is a vasoconstrictor peptide released from endothelial cells that is known to cause prostaglandin (PG) release. The mechanism remains unclear. To determine whether the protein kinase C (PKC) signaling pathway is stimulated by endothel
Autor:
G.K. Oriji, Harry R. Keiser
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 57:135-141
Angiotensin II (Ang II) stimulation of vascular smooth muscle results in a myriad of intracellular signals that interact to produce the final physiologic response of the cell. We used rat aortic rings to investigate the role of protein kinase C (PKC)
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 55:309-313
Endothelin (ET) is a vasoconstrictor peptide released from endothelial cells that is known to cause prostaglandin release. The mechanism remains unclear. To determine whether the protein kinase C (PKC) signaling pathway is stimulated by endothelin, w
Autor:
N. Schanz, G.K. Oriji
Publikováno v:
Prostaglandins, leukotrienes, and essential fatty acids. 65(5-6)
Cyclosporine A (CsA) is an immunosuppressive agent, which also causes hypertension. The effect of CsA on vascular responses was determined in Sprague-Dawley rats and rat aortic rings. Male rats weighing 250-300 g were given either CsA (25 mg/kg/day)
Autor:
G.K. Oriji
Publikováno v:
Prostaglandins, leukotrienes, and essential fatty acids. 65(2)
Angiotensin II (Ang II) has been shown to cause Prostaglandin F(2 alpha)(PGF(2 alpha)) release in neonatal rat ventricular myocytes and smooth muscle cells. In these cells, Ang II has also been shown to regulate growth. We used neonatal rat ventricul
Autor:
G.K. Oriji, Harry R Keiser
Publikováno v:
American journal of hypertension. 12(11 Pt 1)
Chronic treatment with cyclosporine A (CsA), an immunosuppressive agent, causes hypertension. The effect of CsA on vascular responses was determined in Sprague-Dawley rats and isolated rat aortic rings. Male rats weighing 250 to 300 g were given eith
Autor:
G.K. Oriji
Publikováno v:
Prostaglandins, leukotrienes, and essential fatty acids. 61(2)
Angiotensin II (Ang II) has been shown to stimulate the release of immunoreactive endothelin (ET) from cultured bovine ECs. Also, Ang II activates phospholipase A 2 (PLA 2 ) in various tissues, resulting in the release of arachidonic acid and formati