Zobrazeno 1 - 10
of 51
pro vyhledávání: '"G.K. Mulholland"'
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 16:1280-1287
The development and characterization of new receptor ligands for in vivo binding assays are often both lengthy and expensive. It is therefore desirable to predict the suitability of a ligand early in the process of its evaluation. In the present stud
Autor:
Kirk A. Frey, R. Del Rosario, David L. Gildersleeve, Y. W. Jung, G.K. Mulholland, Donald M. Wieland, M. E. Van Dort, David M. Raffel, David E. Kuhl, Phillip S. Sherman
Publikováno v:
ChemInform. 27
Autor:
T.L. Pisani, S.B. Demattos, Charlotte A. Otto, G.K. Mulholland, Phillip S. Sherman, G. Hingorani
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 18:557-561
The localization of quaternized muscarinic receptor (mAChR) antagonists, [“C]methyl tropanyl benzilate ([“CIMTRB) and [“Clmethyl quinuclidinyl benzilate ([“CIMQNB), in rat pituitary was compared to that of [“Cltropanyl benzilate ([“CJTRB)
Autor:
Douglas M. Jewett, Richard D. Hichwa, Donald M. Wieland, G.K. Mulholland, Robert A. Koeppe, Bernard W. Agranoff, David E. Kuhl, Richard E. Ehrenkaufer, James E. Carey, Kirk A. Frey
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 12(1)
Cerebral muscarinic cholinergic receptors were imaged and regionally quantified in vivo in humans with the use of [11C]scopolamine and positron emission tomography. Previous studies in experimental animals have suggested the utility of radiolabeled s
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 26:412-414
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 26:378-380
Polymeric reagents are particularly valuable aids in radiopharmaceutical synthesis where fast, simple and easily automated chemical operations are necessary. Nucleophilic radiofluorination is an operation which could be simplified through use of poly
Autor:
S.E. Perry, Susan J. Fisher, Phillip S. Sherman, Charlotte A. Otto, R. Combs, G.K. Mulholland
Publikováno v:
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology. 16(1)
A series of muscarinic antagonists were screened as potential receptor imaging agents. (+)2α-tropanyl benzilate (TRB), N-methyl-4-piperidyl benzilate (NMPB) and several analogs amenable to labeling with positron emitting isotopes were evaluated for
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 26:484-485
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 26:192-193
be irradiated at m re intense beam currents. However, a combination of factors presently limit [18F]fluoride ion production from small volume l80 water targets under high current irradiation conditions. Inadequate target cooling or a sharply focused
Autor:
Robert A. Koeppe, Charlotte A. Otto, Douglas M. Jewett, Kirk A. Frey, G.K. Mulholland, Michael R. Kilbourn, David E. Kuhl, Phillip S. Sherman
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 26:202-203