Zobrazeno 1 - 10
of 83
pro vyhledávání: '"G.J. van Esch"'
Autor:
Marianne Wolthuis, Engelina M. den Tonkelaar, A.G. Rauws, R. Kroes, Hanneke Berkvens, M.J. van Logten, G.J. van Esch
Publikováno v:
Toxicology. 2:257-267
A 90-day toxicity study was carried out in rats on diets containing 0, 75, 300, 1200, 4800 and 19200 ppm sodium bromide. The animals on the highest level did not groom themselves sufficiently and exhibited signs of motor incoordination. The male anim
Publikováno v:
Water Research. 12:687-690
Publikováno v:
Food and Cosmetics Toxicology. 12:671-679
In a lifetime (29-month) carcinogenicity study, rats were treated with lead arsenate (PbHAsO 4 ) or sodium arsenate (Na 2 HAsO 4 ·7H 2 O) and the possibility that diethylnitrosamine (DENA) may exert a synergistic or additive action on the effects of
Publikováno v:
Water Research. 9:1163-1169
A short- and long-term toxicity study with α-hexachlorocyclohexane (α-HCH) was carried out with freshwater organisms of different trophic levels (algae, crustaceae and fishes). In this study mortality, immobilization, growth, reproduction, histopat
Publikováno v:
Environmental Research. 41:466-480
Experiments were performed to study the influence of concentration, exposure pattern, and length of exposure on the degree and extent of morphological alterations in the NO2-exposed rat lung. Four weeks of continuous exposure to 20 mg NO2/m3 consecut
Publikováno v:
Toxicology. 8:231-249
The inhalation toxicity of peroxyacetyl nitrate (PAN) was examined in acute (single exposure), subacute (4-wk repeated exposure) and subchronic (13-wk repeated exposure) studies in rats. The 4-hr LC50 was found to be 95 ppm. In the 4-wk study rats we
Publikováno v:
Toxicology. 19:139-150
The carcinogenicity of maleic hydrazide is discussed by several national and international organizations because of contradictory results of a number of carcinogenecity studies carried out in the past. Because maleic hydrazide is used in agriculture
Autor:
A. Minderhoud, R. Kroes, D.M.A. Vonk-Visser, G.J. van Esch, G.J.A. Speijers, E.M. Den Tonkelaar, J.M. Berkvens
Publikováno v:
Toxicology. 7:11-21
A range-finding experiment with strontium chloride hexahydrate (0, 3, 30, 300 and 3000 ppm in the diet) and subsequently a 90-day test with the same compound at dose levels of 0, 75, 300, 1200 and 4800 ppm in a semi-purified diet was carried out with
Autor:
H.G. Verschuuren, J.M. Berkvens, A.G. Rauws, Engelina M. den Tonkelaar, P.W. Helleman, P.L. Schuller, G.J. van Esch, R. Kroes
Publikováno v:
Toxicology. 6:107-123
Four groups, each of 25 male and 25 female weanling rats, were given dietary levels of 0, 0.1, 0.5 and 2.5 ppm MeHgCl for 2 years. Observations were made on behaviour, growth, food intake, haematology, serum enzymes, urinalysis, microsomal liver enzy
Publikováno v:
Science of The Total Environment. 47:427-432
A lifetime carcinogenicity study was carried out in Wistar rats, with a mixture of the following halogenated hydrocarbons: trichloromethane, tetrachloromethane, monobromodichloromethane, trichloroethylene, tetrachloroethylene, 1,2,-dichlorobenzene, 1