Zobrazeno 1 - 10
of 71
pro vyhledávání: '"G.E. Mawer"'
Autor:
G.E. Mawer
Publikováno v:
Current Anaesthesia & Critical Care. 8:126-132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6930dbd789741ee1ab61d543f05f93a0
https://doi.org/10.1016/s0953-7112(97)80043-9
https://doi.org/10.1016/s0953-7112(97)80043-9
Autor:
G.E. Mawer, Barbara J. Pleuvry
Publikováno v:
Pharmacology & Therapeutics. 68:209-231
The advent of new antiepileptic drugs (AED) has increased the opportunities for interaction. Clinicians seek therapeutic interactions in which two AED together have greater efficacy than either drug alone; there are case reports of such, but few pros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b76661fc96818f075e4775b0b326d6
https://doi.org/10.1016/0163-7258(95)02006-3
https://doi.org/10.1016/0163-7258(95)02006-3
Publikováno v:
British Journal of Clinical Pharmacology. 35:14-19
1. The influence of pharmaceutical formulation on the plasma drug concentration-time curve and the psychomotor responses to 400 mg carbamazepine has been assessed in 12 healthy male volunteers; three formulations and placebo were compared in a random
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4e7451425fa6b667fb0992b44ad2d4
https://doi.org/10.1111/j.1365-2125.1993.tb05664.x
https://doi.org/10.1111/j.1365-2125.1993.tb05664.x
Autor:
G.E. Mawer, P. B. C. Fenwick, Alan Richens, W Lawler, M.J. Noronha, Simon Shorvon, Stephen W. Brown, David Taylor, David Chadwick, Frank M. C. Besag, Tim Betts
Publikováno v:
Lancet (London, England). 335(8689)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce095f50493f116b6ee19d8e47c04908
https://pubmed.ncbi.nlm.nih.gov/1968598
https://pubmed.ncbi.nlm.nih.gov/1968598
1. The respiratory and psychomotor effects of two benzodiazepines used mainly as anticonvulsants were compared in healthy volunteers, using a double-blind placebo controlled design. 2. Clobazam (10 and 20 mg) produced significantly fewer psychomotor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f67c076d0a54b656de8f96bbc6bafc
https://europepmc.org/articles/PMC1380080/
https://europepmc.org/articles/PMC1380080/
Publikováno v:
British Journal of Clinical Pharmacology. 1:163-168
1 A preliminary survey showed that many outpatients with partially controlled epilepsy had serum concentrations of phenytoin below the recommended therapeutic range (10-20 μg/ml). A phenytoin tolerance test was devised with the intention of predicti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf984790b881180c2c390336ad4e56ce
https://doi.org/10.1111/j.1365-2125.1974.tb00226.x
https://doi.org/10.1111/j.1365-2125.1974.tb00226.x
Publikováno v:
British Journal of Clinical Pharmacology. 3:231-237
A search for patient variables relevant to digoxin dose requirements was made in fourty-three patients with a wide range of renal and hepatic function. The daily dose of digoxin to achieve a mean serum concentration of 1.5 ng/ml, the standardized dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856a8913c0b6fff7ecab77aaa6a956e2
https://doi.org/10.1111/j.1365-2125.1976.tb00597.x
https://doi.org/10.1111/j.1365-2125.1976.tb00597.x
Autor:
G.E. Mawer, Sylvia M. Dobbs
Publikováno v:
Journal of Infectious Diseases. 134:S114-S117
The aminoglycoside antibiotics gentamicin and tobramycin were given to six healthy volunteers by intravenous injection. A dose of 80 mg was injected within 1 min. The curves relating serum concentration to time did not differ significantly for the tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77035f613b6c95c7dbfec61c53f9f3f
https://doi.org/10.1093/infdis/134.supplement_1.s114
https://doi.org/10.1093/infdis/134.supplement_1.s114
Publikováno v:
Chemotherapy. 33:68-76
Without treatment all mice died after receiving 10(3) Klebsiella pneumoniae by intraperitoneal injection. Nevertheless, it was possible to delay treatment for 12 h and still observe a therapeutic response from im gentamicin (5 mg/kg). This gave initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b9474a71f2306d1bd6657ff88241a92
https://doi.org/10.1159/000238477
https://doi.org/10.1159/000238477
Autor:
P. M. Wilkinson, G.E. Mawer
Publikováno v:
British Journal of Clinical Pharmacology. 1:241-247
1 Adriamycin was administered as a single intravenous dose. The plasma concentration in man and rat decayed as a double exponential function of time. 2 A two compartment model was used to predict plasma and tissue concentrations in man and the rat. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d3b04d6d2a33b82ae015e936325afd
https://doi.org/10.1111/j.1365-2125.1974.tb00244.x
https://doi.org/10.1111/j.1365-2125.1974.tb00244.x