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Autor:
G.Creston Campbell, Krishnaswamy S. Raghavan, Anil Dwivedi, Munir A. Hussain, Gregory A. Nemeth
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 12:777-785
DuP 747, a selective kappa agonist analgesic, was found to have at least two polymorphic forms, and this was confirmed by X-ray powder diffraction. DSC and thermomicroscopic studies indicated the polymorphic pair to be monotropic. Solubility studies