Zobrazeno 1 - 10
of 58
pro vyhledávání: '"G.-One Ahn"'
Autor:
Gi-Sue Kang, Young-Eun Kim, Ho Rim Oh, Hye-Ju Jo, Seoyeon Bok, Yoon Kyung Jeon, Gi Jeong Cheon, Tae-Young Roh, Young-Tae Chang, Do Joong Park, G-One Ahn
Publikováno v:
Laboratory Animal Research, Vol 40, Iss 1, Pp 1-16 (2024)
Abstract Background Uncoupling protein 1 (UCP1) is a proton uncoupler located across the mitochondrial membrane generally involved in thermogenesis of brown adipose tissues. Although UCP1 is known to be strongly expressed in brown adipocytes, recent
Externí odkaz:
https://doaj.org/article/be1890961b5b41158df67111966ede78
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 11, Pp 2300-2307 (2023)
Abstract Adipose tissues, composed of various cell types, including adipocytes, endothelial cells, neurons, and immune cells, are organs that are exposed to dynamic environmental challenges. During diet-induced obesity, white adipose tissues experien
Externí odkaz:
https://doaj.org/article/605f485328ec4cb48704816fccc782f0
DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs): Beyond the DNA Double-Strand Break Repair
Publikováno v:
Molecules and Cells. 46:200-205
Autor:
Samuel Strober, Edgar G. Engleman, Robert N. Negrin, Judith A. Shizuru, Sussan Dejbakhsh-Jones, Kent Jensen, Holbrook Kohrt, Nigel Zhang, Suparna Dutt, G-One Ahn, Justin Kenkel, Antonia M.S. Mueller, Jeanette Baker, Alexander Filatenkov
Supplementary Figures 1-4. Supplementary Figure 1. In vitro suppressive function of tumor-infiltrating MDSC 3 days after LTI, and analysis of CD8+CD11+ dendritic cell tumor infiltration after LTI. Supplementary Figure 2. PDL-1 and CD62L expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102d71174f740652bc7679ee11b40dbc
https://doi.org/10.1158/1078-0432.22456569
https://doi.org/10.1158/1078-0432.22456569
Autor:
Samuel Strober, Edgar G. Engleman, Robert N. Negrin, Judith A. Shizuru, Sussan Dejbakhsh-Jones, Kent Jensen, Holbrook Kohrt, Nigel Zhang, Suparna Dutt, G-One Ahn, Justin Kenkel, Antonia M.S. Mueller, Jeanette Baker, Alexander Filatenkov
Purpose: The goals of the study were to elucidate the immune mechanisms that contribute to desirable complete remissions of murine colon tumors treated with single radiation dose of 30 Gy. This dose is at the upper end of the ablative range used clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50f8ac4d8fe37fffed567dbb948986b
https://doi.org/10.1158/1078-0432.c.6523350.v1
https://doi.org/10.1158/1078-0432.c.6523350.v1
Autor:
Samuel Strober, Edgar G. Engleman, Robert N. Negrin, Judith A. Shizuru, Sussan Dejbakhsh-Jones, Kent Jensen, Holbrook Kohrt, Nigel Zhang, Suparna Dutt, G-One Ahn, Justin Kenkel, Antonia M.S. Mueller, Jeanette Baker, Alexander Filatenkov
Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f612b1ad519e3903f19956e44f30aac
https://doi.org/10.1158/1078-0432.22456572
https://doi.org/10.1158/1078-0432.22456572
Supplementary Table 1 from Optimized Clostridium-Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA Cross-Linking Agent PR-104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad21e7799cc42c0d035bf8ab0a961a0c
https://doi.org/10.1158/0008-5472.22375538
https://doi.org/10.1158/0008-5472.22375538
We have previously shown that spores of the nonpathogenic clostridial strain C. sporogenes genetically engineered to express the E. coli–derived cytosine deaminase gene are effective in converting systemically injected nontoxic 5-fluorocytosine int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdf1163fd73172d9605cd124ac77a1cd
https://doi.org/10.1158/0008-5472.c.6497861
https://doi.org/10.1158/0008-5472.c.6497861
Autor:
Young-Eun Kim, Minji Lee, Hyejung Gu, Jeongwoo Kim, Seongju Jeong, Sujin Yeo, You Jeong Lee, Sin-Hyeog Im, Young-Chul Sung, Hak Jae Kim, Irving L. Weissman, G-One Ahn
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 7 (2018)
Inflammatory bowel disease (IBD) is a chronic inflammatory disease, in which the intestinal epithelium loses its barrier function. Given the existence of the oxygen gradient in the intestinal epithelium and that inflammation further contributes to th
Externí odkaz:
https://doaj.org/article/27fd7b4fc5ca408b9d482493727d6341
Autor:
Kyung Tae Hong, Do Hoon Kwon, Hyun-Suk Lim, Min Hyeon Shin, Jiwon Heo, Hoibin Jeong, Jun-Seok Lee, Misook Oh, G-One Ahn, Hyun Kyu Song, Yeongju Lee, Ganesh A. Sable
Publikováno v:
Angewandte Chemie International Edition. 59:17548-17555
Aberrantly elevated steroid receptor coactivator-1 (SRC-1) expression and activity are strongly correlated with cancer progression and metastasis. Here we report, for the first time, the development of a proteolysis targeting chimera (PROTAC) that is