Zobrazeno 1 - 10
of 165
pro vyhledávání: '"G.-A. Hoyer"'
Publikováno v:
Chromatographia. 57:S9-S12
Autor:
G.-A. Hoyer
Publikováno v:
Computer Aided Drug Design in Industrial Research ISBN: 9783662031438
The main goal of this workshop is not so much to present the latest scientific results but to talk about the advantages and disadvantages of computational chemistry in supporting research in pharmaceutical industry. I hope that we will come to the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71059286c21d95604fc92aa424a473e8
https://doi.org/10.1007/978-3-662-03141-4_1
https://doi.org/10.1007/978-3-662-03141-4_1
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 19(2)
The metabolism of the steroidal aromatase inhibitor atamestane was studied in the rat, the cynomolgus monkey and in the human. Metabolite patterns were recorded in plasma, urine and bile (rat only) before and after enzymatic cleavage of sulfate and g
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 21(4)
The metabolic pathway of DL-rolipram was studied in two animal species and in man. Metabolites were isolated from rat, rhesus monkey, and from human urine by preparative HPLC and identified by MS and NMR analysis. In total, the structures of 7 degrad
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 21(2)
The metabolic pathway of the dopaminagonistic ergoline derivative, proterguride, was studied in vitro in a rat liver perfusion experiment. Metabolites were isolated by preparative HPLC and identified by MS and NMR analyses. In total, seven compounds
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 19(5)
After the parenteral administration of the 3H-labeled prostaglandin E2-analogue (PGE2-analogue) to three healthy women, a number of metabolites were observed in the plasma, some of them still potentially pharmacologically active. The metabolite patte
Publikováno v:
Fortschritte der Neurologie-Psychiatrie. 58(7)
This is a report on two male patients aged 22 and 43 years, respectively, who developed a fatal progressive demential syndrome that lead to the death of one after 16 months and of the other patient after 25 months and that presented with the typical
Autor:
G.-A. Hoyer
Publikováno v:
Fresenius' Journal of Analytical Chemistry. 360:743-744
Publikováno v:
Chemische Berichte. 107:128-134
An 54 15,16-Methylensteroiden wurden Untersuchungen mit NMR, MS und CD durchgefuhrt, um allgemeine Gesetzmasigkeiten fur ihre Zuordnung zur α-oder β-Reihe aufzufinden. Nach NMR lassen sich die Verbindungen uber die Signallagen der 13-Methyl-gruppe
Publikováno v:
Journal of Medical Primatology. 17:19-29
Hydroxypregnanolone is the most abundant progesterone metabolite in the urine of marmoset monkeys (Callithrix jacchus). The substance is excreted as conjugate. The concentration of this steroid may be monitored by high performance, thin layer chromat