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Akademický článek

Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids

Autor: S. Randriamanantsoa, A. Papargyriou, H. C. Maurer, K. Peschke, M. Schuster, G. Zecchin, K. Steiger, R. Öllinger, D. Saur, C. Scheel, R. Rad, E. Hannezo, M. Reichert, A. R. Bausch

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

Pancreatic ductal adenocarcinomas (PDAC) exhibit complex morphologies challenging to capture in organoid models. Here, the authors develop PDAC organoids that can recreate branched structures and, with the use of a minimal mathematical model, shed li

Externí odkaz: https://doaj.org/article/49f2bb70c88b4e1d8aac11e93e339bcd

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Stereoselective intramolecular cycloadditions of homochiral nitrile imines: synthesis of enantiomerically pure 3,3a-dihydro-pyrazolo[1,5-a][1,4]benzodiazepine-6(4H)-ones

Autor: Giorgio Molteni, Alessandro Ponti, Tullio Pilati, Luisa Garanti, Gianluigi Broggini, G. Zecchi

Publikováno v: Tetrahedron: asymmetry
info:cnr-pdr/source/autori:G. Broggini, L. Garanti, G. Molteni, T. Pilati, A. Ponti, G. Zecchi/titolo:Stereoselective Intramolecular Cycloadditions of Homochiral Nitrile Imines: Synthesis of Enantiomerically Pure 3,3a-dihydro-pyrazolo[1,5-a][1,4]benzodiazepine-6(4H)-ones/doi:10.1016%2FS0957-4166(99)00227-X/rivista:Tetrahedron: asymmetry (Print)/anno:1999/pagina_da:2203/pagina_a:2212/intervallo_pagine:2203–2212/volume:10

Starting from the commercially available ( S )-1-phenylethylamine, we have synthesised the homochiral hydrazonoyl chlorides 4 . The intramolecular cycloaddition of the corresponding nitrile imines 5 gave the diastereoisomeric 3,3a-dihydro-pyrazolo[1,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a41d447cbcc7849dea6d1ad3f01591c
https://doi.org/10.1016/s0957-4166(99)00227-x

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[A concertation experience: prevention of WMSDs in workmanship of Parmigiano-Reggiano]

Autor: G, Zecchi

Publikováno v: Giornale italiano di medicina del lavoro ed ergonomia. 34

The dairy industry of Parmigiano-Reggiano represents in Emilia a resource and an important source of employment. A Protected Designation of Origin (DOP) regulates all stages of processing of milk into cheese "forms" in excess of 40 kg weight, favouri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::788cf8c285f840f75dc60580553997c4
https://pubmed.ncbi.nlm.nih.gov/23405696

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