Zobrazeno 1 - 10 of 92 pro vyhledávání: '"G. Zea-Flores"'
1
The Onchocerciasis Elimination Program for the Americas: a history of partnership Programa de Eliminación de la Oncocercosis para las Américas: historia de solidaridad
Autor: J Blanks, F Richards, F Beltrán, R Collins, E Álvarez, G. Zea Flores, B Bauler, R Cedillos, M Heisler, D Brandling-Bennett, W Baldwin, M Bayona, R Klein, M Jacox
Publikováno v: Revista Panamericana de Salud Pública, Vol 3, Iss 6, Pp 367-374 (1998)
The decision in 1987 by the pharmaceutical firm Merck & Co. to provide Mectizan® (ivermectin) free of charge to river blindness control programs has challenged the international public health community to find effective ways to distribute the drug t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::8abd95527d392633f7f6d99fb9176238
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49891998000600002
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2
Comparison of the sensitivity of different geographical isolates of Onchocerca volvulus microfilariae to ivermectin: effects of exposure to drug on development in the blackfly Simulium ornatum
Autor: Vincent P.K. Titanji, G. Zea-Flores, Simon Townson, K. Awadzi, S.K. Tagboto, J. Castro
Publikováno v: Transactions of the Royal Society of Tropical Medicine and Hygiene. 88:237-241
Four geographical isolates (Ghana forest, Ghana savannah, Cameroon forest, Guatemala) of Onchocerca volvulus microfilariae (mf) and O. lienalis mf (UK) were examined for their sensitivity to ivermectin by incubation in vitro in drug followed by asses
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875beba58b25c97ca77eb859260ce297
https://doi.org/10.1016/0035-9203(94)90313-1
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3
Guatemalan human onchocerciasis. II. Evidence for IgG3 involvement in acquired immunity to Onchocerca volvulus and identification of possible immune-associated antigens
Autor: A E Boyer, V C Tsang, M L Eberhard, G Zea-Flores, A Hightower, J B Pilcher, R Zea-Flores, W Zhou, C B Reimer
Publikováno v: The Journal of Immunology. 146:4001-4010
Ag-specific isotypic differences in immune response to Onchocerca volvulus Ag were assessed for 778 long term residents of endemic Guatemalan areas by quantitative ELISA with 5-min incubation steps and immunoblot. The study population was separated i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78b809def6bfc952603ddc47ac0e4e86
https://doi.org/10.4049/jimmunol.146.11.4001
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4
Guatemalan human onchocerciasis. I. Systematic analysis of patient populations, nodular antigens, and specific isotypic reactions
Autor: V C Tsang, A E Boyer, J B Pilcher, M L Eberhard, C B Reimer, G Zea-Flores, R Zea-Flores, W Zhou, F O Richards
Publikováno v: The Journal of Immunology. 146:3993-4000
The population from five Guatemalan plantations in areas endemic for onchocerciasis was surveyed, and 1032 individuals were recruited to participate in our study. From physical examination, past clinical history (5 to 8 yr), laboratory evidence and s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c86f5dcc70602cc8a6d55d2f2d535b8
https://doi.org/10.4049/jimmunol.146.11.3993
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5
The Onchocerciasis Elimination Program for the Americas: a history of partnership
Autor: E Alvarez, Robert E. Klein, F Beltrán, D Brandling-Bennett, M Heisler, M Jacox, G Zea Flores, J Blanks, W Baldwin, M Bayona, Richard C. Collins, R Cedillos, F Richards, B Bauler
Publikováno v: Revista Panamericana de Salud Pública, Vol 3, Iss 6, Pp 367-374 (1998)
The decision in 1987 by the pharmaceutical firm Merck & Co. to provide Mectizan® (ivermectin) free of charge to river blindness control programs has challenged the international public health community to find effective ways to distribute the drug t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b0f5d062bbbf7f779203eb9e38ce09
https://pubmed.ncbi.nlm.nih.gov/9734217
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6
Influence of food related to dose on the pharmacokinetics of amocarzine and of its N-oxide metabolite, CGP 13 231, after oral administration to 20 onchocerciasis male patients from Guatemala
Autor: J B, Lecaillon, A A, Poltera, G, Zea-Flores, I, de Ramirez, A, Nowell de Arevalo
Publikováno v: Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ). 42(3)
Twenty male patients from Guatemala infected with Onchocerca volvulus received a 3 mg/kg oral dose of amocarzine twice daily for three days. The patients were randomly assigned to the sequence fasting/non-fasting and non-fasting/fasting for the morni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a2e3b501d050be65c8abc1a067c8f4b6
https://pubmed.ncbi.nlm.nih.gov/1801154
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7
Amocarzine investigated as oral onchocercacidal drug in 272 adult male patients from Guatemala. Results from three dose regimens spread over three days
Autor: G, Zea-Flores, F, Beltranena, A A, Poltera, M, Lopez, M, Moran, C E, Zea-Flores, I, de Ramirez, J B, Lecaillon, F, Zak, M, Palomo
Publikováno v: Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ). 42(3)
The clinical investigations with three types of a three days regimen of amocarzine permitted to adjust the fixed dosing to the body weight related dosing and subsequently the administration of amocarzine from fasting state to drug intake after food.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b7bd2a0c9ccd052d8810031b4f5f6029
https://pubmed.ncbi.nlm.nih.gov/1801152
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8
Use of an ophthalmologic ultrasoundscanner in human onchocercal skin nodules for non-invasive sequential assessment during a macrofilaricidal trial with amocarzine in Guatemala. The first experiences
Autor: A A, Poltera, O, Reyna, G, Zea-Flores, F, Beltranena, A, Nowell de Arevalo, F, Zak
Publikováno v: Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ). 42(3)
Ultrasonography of onchocercal skin nodules was performed with an ophthalmologic real time linear scanner with a B probe of 10 MHz. A clinical trial in Guatemala with amocarzine (CGP 6140)--a new oral macrofilaricidal compound--investigated three rep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2a27f910685e7d5e385d32d1e00876b5
https://pubmed.ncbi.nlm.nih.gov/1801157
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9
Longterm follow-up of onchocerciasis patients in Latin America after treatment and retreatment with amocarzine. Preliminary results
Autor: A A, Poltera, G, Zea-Flores, R, Guderian, H P, Striebel, M, Moran
Publikováno v: Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ). 42(3)
Amocarzine has been reported to have onchocercacidal effects. Four months posttherapy the majority of adult worms were dead or moribund. The effect of skin microfilariae lasted up to one year as reflected by markedly reduced microfilaridermia. Since
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8be896bda68612c1ef23aafd0ff048dd
https://pubmed.ncbi.nlm.nih.gov/1801158
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10
Fine structure of microfilariae in the skin of onchocerciasis patients after exposure to amocarzine
Autor: G, Büttner, G, Zea-Flores, A A, Poltera, D W, Büttner
Publikováno v: Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ). 42(3)
Transmission electron microscopy was used to demonstrate the effects of amocarzine (CGP 6140) on the fine structure of Onchocerca volvulus microfilariae (mf) in skin biopsies from patients treated orally in Guatemala or transepidermally exposed in Li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b3ff000c5f752fa08305ced428ae06b4
https://pubmed.ncbi.nlm.nih.gov/1801159
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