Zobrazeno 1 - 10
of 39
pro vyhledávání: '"G. Wisman"'
Autor:
Tushar Tomar, Jong, Steven De, Alkema, Nicolette, Rieks Hoekman, Meersma, Gert, Klip, Harry, Zee, Ate, G. Wisman
a Systematic representation of F3 PDXs and their treatment schedule. b Global distribution of 450 K methylation probes of the raw data of PDX-36, untreated or treated, tumor samples. c DNA methylation level of each sample type according to HIL CpG cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3a4a958e18b34bb4e33935333d8598
Autor:
Tushar Tomar, Jong, Steven De, Alkema, Nicolette, Rieks Hoekman, Meersma, Gert, Klip, Harry, Zee, Ate, G. Wisman
a Change in tumor growth (percentages) of PDX-36, -37, and -56 during treatment with DAC (2.5 mg/kg, thrice per week) or vehicle for 4 weeks (n = 3 mice per group). b Comparative analysis of significant differentially methylated CpG sites among DAC-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13de87dbe4914d07d0aa64cf8d9c41bc
Autor:
Tushar Tomar, Jong, Steven De, Alkema, Nicolette, Rieks Hoekman, Meersma, Gert, Klip, Harry, Zee, Ate, G. Wisman
a Clinicopathological features of transplanted HGSOC tumors. b Representation of patients and their corresponding PDX tumor samples used in this study. c All preprocessing of 450 K data of each sample. d DNA methylation level of each sample type acco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10836ae9ab58ef39b70acc63869f6fc4
Autor:
Tushar Tomar, Jong, Steven De, Alkema, Nicolette, Rieks Hoekman, Meersma, Gert, Klip, Harry, Zee, Ate, G. Wisman
a, b Validation of global methylation using bisulfite pyrosequencing of LINE-1 (a) and ALU-Yb8 (b) in PDX samples treated with either vehicle or cisplatin (4 mg/kg/week) for 4 weeks (n = 3 mice per group). Each bar represents average methylation (%)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a54f248dc2d66e5a1fec58422b8d9fa
Autor:
Teschendorff, Andrew, Shih-Han Lee, Jones, Allison, Fiegl, Heidi, Kalwa, Marie, Wagner, Wolfgang, Kantaraja Chindera, Evans, Iona, Dubeau, Louis, Orjalo, Arturo, Horlings, Hugo, Niederreiter, Lukas, Kaser, Arthur, Yang, Winnie, Goode, Ellen, Fridley, Brooke, Jenner, Richard, Berns, Els, Wik, Elisabeth, Salvesen, Helga, G. Wisman, Zee, Ate Van Der, Davidson, Ben, Trope, Claes, Lambrechts, Sandrina, Vergote, Ignace, Calvert, Hilary, Jacobs, Ian, Widschwendter, Martin
HOTAIR DNAme score in ovarian cancer cell lines and MSCs depending on number of passages after stable HOTAIR transfection (ovarian cancer cells) or after starting in vitro culture (MSCs). The HOTAIR DNAme score is the Pearson correlation coefficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7d423f3a150c40261b019bee00e8ec
Autor:
Teschendorff, Andrew, Shih-Han Lee, Jones, Allison, Fiegl, Heidi, Kalwa, Marie, Wagner, Wolfgang, Kantaraja Chindera, Evans, Iona, Dubeau, Louis, Orjalo, Arturo, Horlings, Hugo, Niederreiter, Lukas, Kaser, Arthur, Yang, Winnie, Goode, Ellen, Fridley, Brooke, Jenner, Richard, Berns, Els, Wik, Elisabeth, Salvesen, Helga, G. Wisman, Zee, Ate Van Der, Davidson, Ben, Trope, Claes, Lambrechts, Sandrina, Vergote, Ignace, Calvert, Hilary, Jacobs, Ian, Widschwendter, Martin
Predicting HOTAIR expression with the 67-CpG DNA methylation signature. A ROC analysis was used to optimize the cutoff of the correlation score between the 67-CpG DNAme signature and the corresponding DNAme of each of the 63 ovarian cancer samples (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544b490ab4245a5e8e60ea05f645a8aa
Autor:
Teschendorff, Andrew, Shih-Han Lee, Jones, Allison, Fiegl, Heidi, Kalwa, Marie, Wagner, Wolfgang, Kantaraja Chindera, Evans, Iona, Dubeau, Louis, Orjalo, Arturo, Horlings, Hugo, Niederreiter, Lukas, Kaser, Arthur, Yang, Winnie, Goode, Ellen, Fridley, Brooke, Jenner, Richard, Berns, Els, Wik, Elisabeth, Salvesen, Helga, G. Wisman, Zee, Ate Van Der, Davidson, Ben, Trope, Claes, Lambrechts, Sandrina, Vergote, Ignace, Calvert, Hilary, Jacobs, Ian, Widschwendter, Martin
Comparison of the predictive score of our HOTAIR DNA methylation signature (red) to those obtained from 1000 randomized signatures (green) (randomized signatures have the same number of CpGs as the original signature). To further substantiate our res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464cc3e1f9eb604d8c13cdb2b09e30a9
Autor:
Teschendorff, Andrew, Shih-Han Lee, Jones, Allison, Fiegl, Heidi, Kalwa, Marie, Wagner, Wolfgang, Kantaraja Chindera, Evans, Iona, Dubeau, Louis, Orjalo, Arturo, Horlings, Hugo, Niederreiter, Lukas, Kaser, Arthur, Yang, Winnie, Goode, Ellen, Fridley, Brooke, Jenner, Richard, Berns, Els, Wik, Elisabeth, Salvesen, Helga, G. Wisman, Zee, Ate Van Der, Davidson, Ben, Trope, Claes, Lambrechts, Sandrina, Vergote, Ignace, Calvert, Hilary, Jacobs, Ian, Widschwendter, Martin
Enrichment odds ratios (OR) with 95Â % confidence intervals for PCGTs according to different definitions among CpGs undergoing significant hyper- and hypomethylation with HOTAIR (HA) expression (top 500 CpGs) in ovarian cancer samples (INNSBRUCK set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1cd30dae2de568d2d36563002bd69a
Autor:
Teschendorff, Andrew, Shih-Han Lee, Jones, Allison, Fiegl, Heidi, Kalwa, Marie, Wagner, Wolfgang, Kantaraja Chindera, Evans, Iona, Dubeau, Louis, Orjalo, Arturo, Horlings, Hugo, Niederreiter, Lukas, Kaser, Arthur, Yang, Winnie, Goode, Ellen, Fridley, Brooke, Jenner, Richard, Berns, Els, Wik, Elisabeth, Salvesen, Helga, G. Wisman, Zee, Ate Van Der, Davidson, Ben, Trope, Claes, Lambrechts, Sandrina, Vergote, Ignace, Calvert, Hilary, Jacobs, Ian, Widschwendter, Martin
Ten-fold internal cross-validations to identify an optimal DNAme signature. Upper panel shows the total misclassification error (y-axis) as a function of the shrinkage threshold (x-axis) used. Lower panel shows the misclassification error for each ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2430ba99ef30bd6859723928f2670ee8
Autor:
Teschendorff, Andrew, Shih-Han Lee, Jones, Allison, Fiegl, Heidi, Kalwa, Marie, Wagner, Wolfgang, Kantaraja Chindera, Evans, Iona, Dubeau, Louis, Orjalo, Arturo, Horlings, Hugo, Niederreiter, Lukas, Kaser, Arthur, Yang, Winnie, Goode, Ellen, Fridley, Brooke, Jenner, Richard, Berns, Els, Wik, Elisabeth, Salvesen, Helga, G. Wisman, Zee, Ate Van Der, Davidson, Ben, Trope, Claes, Lambrechts, Sandrina, Vergote, Ignace, Calvert, Hilary, Jacobs, Ian, Widschwendter, Martin
Clinicopathological characteristics of ovarian cancer patients (INNSBRUCK set) for which HOTAIR expression and DNAme have been done. (PDF 189 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::047bc0607adcc5dce9d5dce91b0515c7