Zobrazeno 1 - 10
of 167
pro vyhledávání: '"G. W. Mayr"'
Autor:
Daniel Pablo Lew, G. W. Mayr, Nicolas Demaurex, C. van Delden, Karl-Heinz Krause, Michelangelo Foti, Jean Jacquet, Jacques Schrenzel
Publikováno v:
Biophysical Journal, Vol. 69, No 6 (1995) pp. 2378-2391
To study the initial kinetics of Ins(1,4,5)P3-induced [Ca2+]i elevations with a high time resolution and to avoid the problem of cell-to-cell heterogeneity, we have used the combined patch-clamp/microfluorimetry technique. The mathematical descriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7c1d99317c5687ea99fa6d0cec9720
https://doi.org/10.1016/s0006-3495(95)80107-4
https://doi.org/10.1016/s0006-3495(95)80107-4
Publikováno v:
The Journal of Immunology. 155:3353-3359
Ca2+ release from intracellular stores is one of the major events transducing extracellular signals into living cells. Recently, a metabolite of nicotinamide adenine dinucleotide+ (NAD+), termed "cyclic adenosine diphosphate-ribose" (cADPr), has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a6b78949616e7809033b7a6718b44bb
https://doi.org/10.4049/jimmunol.155.7.3353
https://doi.org/10.4049/jimmunol.155.7.3353
Publikováno v:
The EMBO Journal. 13:1601-1609
The micro-organism Dictyostelium uses extracellular cAMP to induce chemotaxis and cell differentiation. Signals are transduced via surface receptors, which activate G proteins, to effector enzymes. The deduced protein sequence of Dictyostelium discoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ab52da593e95f0b5242745c0a78262
https://doi.org/10.1002/j.1460-2075.1994.tb06423.x
https://doi.org/10.1002/j.1460-2075.1994.tb06423.x
Autor:
H. C. P. F. Roelen, G. W. Mayr, J.-P. Jansze, J. H. Van Boom, C. E. Dreef, G. A. Van Der Marel
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 1:239-242
The myo -inositol phosphorothioates 6 , 9 , 12 , and 17 were readily accessible from properly protected precursors by phosphitylation with N,N -diisopropyl dibenzyl phosphoramidite ( 1 ), subsequent in situ sulfurization of the intermediate phosphite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f11426d309e5bbe8dc9b4d69dad6ac7
https://doi.org/10.1016/s0960-894x(01)81033-7
https://doi.org/10.1016/s0960-894x(01)81033-7
Publikováno v:
European journal of biochemistry. 267(8)
The intracellular amounts of diphospho-myo-inositol phosphates and InsP6 were determined in Dictyostelium discoideum AX2 throughout the life cycle, including exponential growth, starvation, differentiation, sporulation and spore germination. Similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ba83fb884dbfbc8d42e3683f21ece41
https://pubmed.ncbi.nlm.nih.gov/10759871
https://pubmed.ncbi.nlm.nih.gov/10759871
Autor:
K, Jun, G, Choi, S G, Yang, K Y, Choi, H, Kim, G C, Chan, D R, Storm, C, Albert, G W, Mayr, C J, Lee, H S, Shin
Publikováno v:
Learningmemory (Cold Spring Harbor, N.Y.). 5(4-5)
To define the physiological role of IP(3)3-kinase(A) in vivo, we have generated a mouse strain with a null mutation of the IP(3)3-kinase(A) locus by gene targeting. Homozygous mutant mice were fully viable, fertile, apparently normal, and did not sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce5e4ca644545232b0e81db2f7f61474
https://pubmed.ncbi.nlm.nih.gov/10454357
https://pubmed.ncbi.nlm.nih.gov/10454357
Publikováno v:
Advances in experimental medicine and biology. 419
Intracellular Ca(2+)-signals belong to the major events transducing extracellular signals into living cells. The discovery of (i) a caffeine-sensitive intracellular Ca(2+)-pool in Jurkat T-lymphocytes [1] and (ii) cyclic adenosine diphosphoribose (cA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4fde8028818fe20a36d11bca9bee5d92
https://pubmed.ncbi.nlm.nih.gov/9193685
https://pubmed.ncbi.nlm.nih.gov/9193685
Publikováno v:
The American journal of physiology. 268(6 Pt 1)
To understand how inositol phosphates (InsP) cause Ca2+ influx, we injected 37 highly purified compounds containing a total of 49 InsP positional isomers into Xenopus oocytes. The eight InsP that stimulated Ca2+ influx were those that had the highest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1074f1692af11e9a61a4f16b5e33396
https://pubmed.ncbi.nlm.nih.gov/7611369
https://pubmed.ncbi.nlm.nih.gov/7611369
Autor:
G. W. Mayr
Publikováno v:
Tyrosine Phosphorylation/Dephosphorylation and Downstream Signalling ISBN: 9783642782497
Only cellular PLC# activity can be determined presently without a HPLC or LC instrumentation. However, a state-of-art analysis of the complex metabolism of inositol phosphates and phosphoinositides requires sophisticated sample workup and HPLC analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22716ef41f38178b992deb267ae63c3a
https://doi.org/10.1007/978-3-642-78247-3_22
https://doi.org/10.1007/978-3-642-78247-3_22
Autor:
G. W. Mayr
Publikováno v:
Idiopathic Dilated Cardiomyopathy ISBN: 9783642778933
In recent years it has been clearly established (see reviews [24, 66]) that the myocardium contains all the elements of the inositide signaling system. It has also been established that a number of agonists activate the key enzyme of inositide signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ea1dc3fd01c14abe604c0c2887473a4
https://doi.org/10.1007/978-3-642-77891-9_23
https://doi.org/10.1007/978-3-642-77891-9_23