Zobrazeno 1 - 9
of 9
pro vyhledávání: '"G. W. L. James"'
Publikováno v:
British Journal of Pharmacology. 34:76-87
1. Nine non-steroidal anti-inflammatory drugs were tested for antagonism of bradykinin-induced bronchoconstriction in guinea-pig lungs in vivo. Only one, benzydamine, was inactive. 2. The descending order of potency of the active anti-inflammatory dr
Publikováno v:
British Journal of Pharmacology. 46:56-65
Summary 1 . A method for the measurement of anaphylactic bronchoconstriction in the rat is described. 2 . Dexamethasone inhibited this response in a dose-related manner. 3 . Disodium cromoglycate antagonized the response. A bell-shaped dose-response
Publikováno v:
Journal of Pharmacy and Pharmacology. 19:837-840
An accurate and rapid method of digitizing large numbers of experimental tracings is possible using a Pencil Follower (D-Mac). Its use in conjunction with a computer has meant that data, hitherto virtually unmanageable, can be subjected to full stati
Autor:
F. L. Parker, G. W. L. James
Publikováno v:
The Journal of pharmacy and pharmacology. 30(4)
The topical application of antibiotics and anti-inflammatory agents is used to reduce inflammation of the middle ear mucosa and irradicate infection. Many of the antibiotic and anti-inflammatory preparations so used contain compounds known to be or a
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 4(1)
The fate of a novel imidazo-benzodiazepine (I) was studied in male rats and rabbits using 14C and 3H-labelled I. In both species the compound was rapidly and widely absorbed after an oral dose of 5 mg/kg to give peak tissue and plasma levels after 1
Publikováno v:
Nature. 212(5060)
ADENOSINE triphosphate (ATP) and related adenosine phosphates cause bronchoconstriction in guinea-pig isolated lungs, and, in relatively high doses, increase air overflow volume in the Konzett-Rossler preparation of guinea-pig lungs in vivo1. ATP eli
Autor:
G. W. L. James, D. B. Garraway
Publikováno v:
The Journal of pharmacy and pharmacology. 9(8)
Pressor and oxytocic activities were separated from a crude extract of pig posterior pituitary tissue using a continuous electrophoretic technique. Both voltage and rate of application were kept constant. The material obtained during the first 24 hou
Autor:
G. W. L. James, J. D. P. Graham
Publikováno v:
Journal of medicinal and pharmaceutical chemistry. 3