Zobrazeno 1 - 10
of 95
pro vyhledávání: '"G. Van Maele-Fabry"'
Publikováno v:
Critical reviews in toxicology, Vol. 48, no. 7, p. 522-539 (2018)
This article summarizes recent experimental and epidemiological data on the genotoxic and carcinogenic activities of cobalt compounds. Emphasis is on the respiratory system, but endogenous exposure from Co-containing alloys used in endoprostheses, an
Autor:
P Bastin, Ans Baeyens, Stephanie Vermeulen, Vincent Haufroid, G. Van Maele-Fabry, Anne Vral, Dominique Lison
Publikováno v:
Toxicology Letters, Vol. 303, p. 72-77 (2019)
Purpose Cd is considered as a genotoxic carcinogen for which a threshold can be identified. This threshold has, however, not been established and the shape of the relationship between Cd exposure and genotoxic effects is unknown. The aim of the prese
Autor:
Jan L. Willems, G. Van Maele-Fabry
Publikováno v:
International Archives of Occupational and Environmental Health. 77:559-570
OBJECTIVES: To analyse data from peer-reviewed, case-referent and cohort studies, studying the occurrence of prostate cancer in pesticide applicators and in some other, related, occupational categories, in order to determine a possible relationship o
Autor:
G. Van Maele-Fabry, Jan L. Willems
Publikováno v:
Occupational and Environmental Medicine. 60:634-642
Aims: To summarise recent literature on the risk of prostate cancer in pesticide related occupations, to calculate the meta-rate ratio, and to compare it to data from meta-analyses previously published. Methods: A meta-analysis of 22 epidemiological
Publikováno v:
Neurotoxicology and Teratology. 19:163-169
The expression domain of Otx2, a gene essential for the development of the fore- and midbrain, has previously been shown to be affected by exposure to all-trans-retinoic acid (AT-RA). However, morphological abnormalities of the fore- and midbrain ind
Publikováno v:
Developmental Brain Research. 93:62-69
Prenatal valproic acid (VPA) exposure results in neural tube defects and in the fetal valproate syndrome (FVS), associated with developmental delay. In the present study we investigate the alterations induced by VPA and one of its metabolite, 4-en-VP
Publikováno v:
Teratology. 53:10-20
The embryotoxic and dysmorphogenic effects of mercuric chloride (HgCl2) have been studied in mouse embryos cultured in vitro. In addition, the alterations induced in the developing branchial nerves and ganglia were analyzed. Mouse embryos with 6-8 pa
Publikováno v:
Toxicology in Vitro. 9:671-675
Rat embryos explanted at the presomite stage and cultured through limb bud stages develop to well formed embryos and exhibit growth and differentiation which mimic those observed in vivo at corresponding stages. In contrast, the culture of presomite
Publikováno v:
Toxicology in Vitro. 7:719-725
The developmental tables of early somite mouse embryos that are presently available from the literature give clear and useful descriptions of the differentiation at successive stages. However, they provide no easy access to the correlation between th
Autor:
M.C. Jacobs, P. Berthet, G. Gofflot, P. Therasse, J.J. Picard, G. Van Maele-Fabry, K. Despontin, J.P. Desager, Jean-Marie Lachapelle, C. Lecart, E. Lenoir
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 7(6)
Sera of 20 patients treated with 20-40 mg isotretinoin/day were tested for embryotoxicity potential. For each patient, the first sample was taken before treatment (control sample) and the second was taken 2 months after the start of treatment (treate