Efficacy assessment of a novel endolysin PlyAZ3aT for the treatment of ceftriaxone-resistant pneumococcal meningitis in an infant rat model.

Autor: Luca G Valente, Ngoc Dung Le, Melissa Pitton, Gabriele Chiffi, Denis Grandgirard, Stephan M Jakob, David R Cameron, Grégory Resch, Yok-Ai Que, Stephen L Leib

Publikováno v: PLoS ONE, Vol 17, Iss 4, p e0266928 (2022)

BackgroundTreatment failure in pneumococcal meningitis due to antibiotic resistance is an increasing clinical challenge and alternatives to antibiotics warrant investigation. Phage-derived endolysins efficiently kill gram-positive bacteria including

Externí odkaz: https://doaj.org/article/09efee4f91354fa48dcd19f870970696

Advancement in design and failure analysis of aluminium foam-filled honeycomb crash absorbers

Autor: G. Valente, H. Ghasemnejad, S. Srimanosaowapak, J. W. Watson

Honeycomb structures are frequently used as energy absorption devices in the automotive and aerospace industry. Many studies have been conducted to optimise these structures and improve crashworthiness behaviour. This paper attempts to improve the cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13be3ca373051b7a6188421f2657faa8
https://dspace.lib.cranfield.ac.uk/handle/1826/19334

Peripheral odontogenic fibroma of the mandible

Autor: F. Cavarra, P. Boffano, A.M. Agnone, G. Santoro, I. Zanellato, G. Valente, V. Rocchetti

Publikováno v: Dental Cadmos.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22a618113d99c9476ea955bf1a5c54c0
https://doi.org/10.19256/d.cadmos.2021.72

Efficacy of phage therapy in preclinical models of bacterial infection: a systematic review and meta-analysis

Autor: Sergio Alejandro Gómez-Ochoa, Melissa Pitton, Luca G Valente, Cristian David Sosa Vesga, Jorge Largo, Andrea Carolina Quiroga-Centeno, Juliana Alexandra Hernández Vargas, Silvia Juliana Trujillo-Cáceres, Taulant Muka, David R Cameron, Yok-Ai Que

Publikováno v: Gómez-Ochoa, Sergio Alejandro; Pitton, Melissa; Valente, Luca G; Sosa Vesga, Cristian David; Largo, Jorge; Quiroga-Centeno, Andrea Carolina; Hernández Vargas, Juliana Alexandra; Trujillo-Cáceres, Silvia Juliana; Muka, Taulant; Cameron, David R; Que, Yok-Ai (2022). Efficacy of phage therapy in preclinical models of bacterial infection: a systematic review and meta-analysis. The Lancet Microbe, 3(12), e956-e968. Elsevier 10.1016/S2666-5247(22)00288-9

BACKGROUND Antimicrobial resistance of bacterial pathogens is an increasing clinical problem and alternative approaches to antibiotic chemotherapy are needed. One of these approaches is the use of lytic bacterial viruses known as phage therapy. We ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1beef1bb2381473a43addc7a5e397bb8
https://boris.unibe.ch/174743/8/G_mez-Ochoa_LancetMicrobe_2022.pdf

Clinical presentation of 54 patients with endogenous hyperinsulinaemic hypoglycaemia: a neurological chameleon (observational study)

Autor: Luca G. Valente, Kwadwo Antwi, Guillaume P. Nicolas, Damian Wild, Emanuel Christ

Publikováno v: Swiss Medical Weekly, Vol 148, Iss 4546 (2018)

BACKGROUND Important causes of endogenous hyperinsulinaemic hypoglycaemia (EHH) in adult patients are insulinoma and adult nesidioblastosis. Data on main symptoms in EHH are scarce and controversial. We analysed main symptoms of patients with EHH in

Externí odkaz: https://doaj.org/article/228c735d2bb649da9259d77db5860a0b