Zobrazeno 1 - 10
of 13
pro vyhledávání: '"G. V. Ilyinskaya"'
Autor:
K. V. Sivak, K. I. Stosman, E. Yu. Kalinina, M. M. Lyubishin, Ya. R. Orshanskaya, T. N. Savateeva-Lyubimova, S. B. Kazakova, D. M. Fedoseeva, A. S. Nazarov, E. I. Radion, S. M. Yudin, A. A. Keskinov, V. V. Makarov, V. S. Yudin, A. O. Zheltukhin, P. O. Vorobyev, D. V. Kochetkov, G. V. Ilyinskaya, A. V. Lipatova, P. M. Chumakov
Publikováno v:
Безопасность и риск фармакотерапии, Vol 0, Iss 0 (2022)
INTRODUCTION. Developing novel medicines based on non-pathogenic enterovirus strains exhibiting oncotropic and oncolytic properties represents an up-to-date and safe approach to complex cancer treatment and postoperative metastasis prevention. Safety
Externí odkaz:
https://doaj.org/article/c3aafa14645e435fa0f9881cad8c8c77
Publikováno v:
Biomedical and Pharmacology Journal. 11:759-767
In mammals a small family of genes called Sestrins play important roles in the maintenance of metabolic and redox homeostasis, suggesting that the genes may positively affect the lifespan and counteract the age-related functional decline. The nematod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cde4eca16cd8fe962388c0517e7af7f
https://doi.org/10.13005/bpj/1430
https://doi.org/10.13005/bpj/1430
Publikováno v:
Molecular Biology. 52:306-322
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fbe4de371f62eaf83d96c09b86b369d
https://doi.org/10.1134/s002689331803010x
https://doi.org/10.1134/s002689331803010x
Publikováno v:
Молекулярная биология. :360-379
Preclinical studies demonstrate that a broad spectrum of human and animal malignant cells can be killed by oncolytic paramyxoviruses, which includes cells of ecto-, endo- and mesodermal origin. In clinical trials, significant reduction or even comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcd034accbd67c51d041ac466d973b2c
https://doi.org/10.7868/s0026898418030023
https://doi.org/10.7868/s0026898418030023
Publikováno v:
Molekuliarnaia biologiia. 52(3)
Preclinical studies demonstrate that a broad spectrum of human and animal malignant cells can be killed by oncolytic paramyxoviruses, which includes cells of ecto-, endo- and mesodermal origin. In clinical trials, significant reduction or even comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b1b9dbd0743efac6ba8faf0eef97555
https://pubmed.ncbi.nlm.nih.gov/29989571
https://pubmed.ncbi.nlm.nih.gov/29989571
Autor:
V. S. Prasolov, Julia E. Kravchenko, P. M. Chumakov, G. V. Ilyinskaya, S. P. Chumakov, Elena I. Frolova
Publikováno v:
Molecular Biology. 42:894-900
An enzymatic assay system was developed to quantify the distribution of recombinant proteins over various cell structures. The system takes advantage of α-complementation of β-galactosidase. The large ω fragment of β-galactosidase is expressed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74add7a8a637bfd16f574a16c4cd0570
https://doi.org/10.1134/s0026893308060095
https://doi.org/10.1134/s0026893308060095
Autor:
Andrei V. Budanov, G. V. Ilyinskaya, P. M. Chumakov, D. V. Kochetkov, P. G. Komarov, Alexey V. Ivanov, L. S. Agapova, E. Strom, Elena I. Frolova
Publikováno v:
Molecular Biology. 41:459-466
Inactivation of tumor suppressor p53 accompanies the majority of human malignancies. Restoration of p53 function causes death of tumor cells and is potentially suitable for gene therapy of cancer. In cervical carcinoma, human papilloma virus (HPV) E6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42ee01005a206149ad5849adef332010
https://doi.org/10.1134/s0026893307030120
https://doi.org/10.1134/s0026893307030120
Autor:
L. S. Agapova, G. V. Ilyinskaya, Peter M. Chumakov, Nikolai A. Turovets, Boris P. Kopnin, Alexey V. Ivanov
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 354:129-138
It has been proposed that p53 tumor-suppressor plays a key role in maintaining genome integrity in mammalian cells. We analyzed karyotype alterations in human and murine cell sublines expressing various exogenous human mutant (His175, Trp248, His273)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fd06f900c3bbb12733127b4c6e2af3
https://doi.org/10.1016/0027-5107(96)00062-0
https://doi.org/10.1016/0027-5107(96)00062-0
Autor:
Anton V. Gorbachev, Danielle D. Kish, Marianne Petro, Robert L. Fairchild, Anna A. Kondratova, Olga A. Guryanova, G. V. Ilyinskaya
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 190(2)
During growth in the host, tumor cells are subjected to the stresses of innate and adaptive immunity (immunoediting), which provoke epigenetic changes in the tumor and increase tumor resistance to these immune responses. Our recent studies in methylc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b33d77dbc868f21e9a800b600146ca
https://pubmed.ncbi.nlm.nih.gov/23241877
https://pubmed.ncbi.nlm.nih.gov/23241877
Autor:
D. V. Kochetkov, Evguenia Strom, Julia E. Kravchenko, Andrei V. Gudkov, Elena I. Frolova, Elena Feinstein, P. M. Chumakov, I. Kovriga, Pavel G. Komarov, G. V. Ilyinskaya, L. S. Agapova
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(17)
Identification of unique features of cancer cells is important for defining specific and efficient therapeutic targets. Mutant p53 is present in nearly half of all cancer cases, forming a promising target for pharmacological reactivation. In addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d4cc2bdb612d1eecdf1cceb06f5667
https://pubmed.ncbi.nlm.nih.gov/18424558
https://pubmed.ncbi.nlm.nih.gov/18424558