Crystal structure of ammonium 3′-azido-3′-de­oxy­thymidine-5′-amino­carbonyl­phospho­nate hemi­hydrate: an anti-HIV agent

Autor: Ivan S. Bushmarinov, G. V. Gurskaya, Maxim V. Jasko, Marina K. Kukhanova

Publikováno v: Acta Crystallographica Section E: Structure Reports
Acta Crystallographica Section E, Vol 70, Iss 11, Pp 396-399 (2014)

The asymmetric unit of the title compound contains one 3′-azido-3′-de­oxy­thymidine-5′amino­carbonyl­phospho­nate (ACP–AZT) anion, half on an NH4 + cation lying on a twofold rotation axis and, in another position occupied with equal prob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0597b7c528e0d2bea7e768e3f2b0ed7f
http://europepmc.org/articles/PMC4257306

Disaccharide nucleosides: The crystal and molecular structure of 2′-O-β-D-ribopyranosylcytidine

Autor: G. V. Gurskaya, N. E. Zhukhlistova, Sergey N. Mikhailov, Ekaterina V. Efimtseva, Georgii V. Bobkov, Yu. V. Nekrasov

Publikováno v: Crystallography Reports. 50:395-399

The crystal structure of a disaccharide nucleoside, 2′-O-β-D-ribopyranosylcytidine, is studied using X-ray diffraction (space group P21, a = 6.827(2) A, b = 12.813(3) A, c = 9.532(2) A, β = 92.934(5)°, V = 832.7(4) A3, Z = 2). The stereochemical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9a88e22a524f5bac3fece8147f7db3f
https://doi.org/10.1134/1.1927597

X-ray diffraction studies of 5-functionalized substituted 1,2,3,4-tetrahydropyrimidin-2-ones(thiones): I. Molecular structures of 5-acetyl-4-ethyl-6-methyl-1,2,3,4-tetrahydropyrimidine-2-thione, 5-acetyl-6-methyl-4-(4-methylphenyl)-1,2,3,4-tetrahydropyrimidine-2-thione, and 5-acetyl-4-(4-methoxyphenyl)-6-methyl-1,2,3,4-tetrahydropyrimidin-2-one

Autor: G. V. Gurskaya, Valery E. Zavodnik, Anatoly D. Shutalev

Publikováno v: Crystallography Reports. 48:92-97

The structures of three 5-acetyl-1,2,3,4-tetrahydropyrimidin-2-ones(thiones), namely, 5-acetyl-4-ethyl-6-methyl-1,2,3,4-tetrahydropyrimidine-2-thione, 5-acetyl-6-methyl-4-(4-methylphenyl)-1,2,3,4-tetrahy-dropyrimidine-2-thione, and 5-acetyl-4-(4-meth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1414a8dda02a5031fa6721ea0fb9f75c
https://doi.org/10.1134/1.1541749

1-[4,5-Bis(hydroxymethyl)-1,2,3-triazol-1-ylmethyl]thymine

Autor: G. V. Gurskaya, Valery E. Zavodnik, Vladimir G. Tsirelson, Adam I. Stash, Sergei G. Zavgorodny

Publikováno v: Acta Crystallographica Section E Structure Reports Online. 61:o1721-o1723

The title compound, C10H13N5O4, can be classed as both a homo-C-nucleoside and an analogue of nucleosides possessing a 1,2,3-triazole ring instead of a furan­ose residue, some derivatives of which are potent antiviral agents. The mutual mol­ecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76c9a3004cae124e045413de8c6aba96
https://doi.org/10.1107/s1600536805014650

5-Acetyl-4,6-dimethyl-1,2,3,4-tetrahydropyrimidin-2-one

Autor: Adam I. Stash, Vladimir G. Tsirelson, Valery E. Zavodnik, G. V. Gurskaya, Anatoly D. Shutalev

Publikováno v: Acta Crystallographica Section E Structure Reports Online. 61:o365-o367

The title compound, C8H12N2O2, belongs to the class of 5-substituted 1,2,3,4-tetrahydro­pyrimidin-2-ones, which exhibit a wide spectrum of biological activities. The conformation of the tetrahydropyrimidine ring is that of a distorted boat. In the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd3a2657a61e3d3cf104359fff6df05c
https://doi.org/10.1107/s1600536805000383