Zobrazeno 1 - 10
of 184
pro vyhledávání: '"G. Uren"'
Autor:
Mathew Van de Pette, Andrew Dimond, António M. Galvão, Steven J. Millership, Wilson To, Chiara Prodani, Gráinne McNamara, Ludovica Bruno, Alessandro Sardini, Zoe Webster, James McGinty, Paul M. W. French, Anthony G. Uren, Juan Castillo-Fernandez, William Watkinson, Anne C. Ferguson-Smith, Matthias Merkenschlager, Rosalind M. John, Gavin Kelsey, Amanda G. Fisher
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Here the authors show that a high-fat diet in pregnant mice can release silencing of the imprinted Dlk1 locus in multiple generations of offspring. They found that this occurs via changes in microRNA expression at the locus of interest, as well as tr
Externí odkaz:
https://doaj.org/article/21c5cdaf517b495e8f2f75239a9fefc7
Autor:
Joanna C. Dawes, Philip Webster, Barbara Iadarola, Claudia Garcia-Diaz, Marian Dore, Bruce J. Bolt, Hamlata Dewchand, Gopuraja Dharmalingam, Alex P. McLatchie, Jakub Kaczor, Juan J. Caceres, Alberto Paccanaro, Laurence Game, Simona Parrinello, Anthony G. Uren
Publikováno v:
Mobile DNA, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background Ligation-mediated PCR protocols have diverse uses including the identification of integration sites of insertional mutagens, integrating vectors and naturally occurring mobile genetic elements. For approaches that employ NGS seque
Externí odkaz:
https://doaj.org/article/cdb46adc21fd43509b19e5cc6b2b40e7
Autor:
Joanna C. Dawes, Anthony G. Uren
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cancer genome sequencing has identified dozens of mutations with a putative role in lymphomagenesis and leukemogenesis. Validation of driver mutations responsible for B cell neoplasms is complicated by the volume of mutations worthy of investigation
Externí odkaz:
https://doaj.org/article/6e78295678eb4b21a0edfe05fac25f66
Autor:
Philip Webster, Joanna C. Dawes, Hamlata Dewchand, Katalin Takacs, Barbara Iadarola, Bruce J. Bolt, Juan J. Caceres, Jakub Kaczor, Gopuraja Dharmalingam, Marian Dore, Laurence Game, Thomas Adejumo, James Elliott, Kikkeri Naresh, Mohammad Karimi, Katerina Rekopoulou, Ge Tan, Alberto Paccanaro, Anthony G. Uren
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Evidence implicating cancer drivers can be sparse when limited to clonal events. Here, the authors present a retrovirus driven in vivo lymphomagenesis time course including hundreds of thousands of subclonal mutations and demonstrate the utility of t
Externí odkaz:
https://doaj.org/article/3cbfb68852e24510a503042bbd7eab4d
Autor:
David J. Adams, Tim Hubbard, Lara S. Collier, Anton Berns, Maarten van Lohuizen, P. Andy Futreal, Michael R. Stratton, David A. Largaespada, Louise van der Weyden, Catherine H. Wilson, Markus Brosch, Alistair G. Rust, Adam Butler, Graham R. Bignell, Jos Jonkers, Lodewyk Wessels, Jeroen de Ridder, Anthony G. Uren, Jaap Kool, Jenny Mattison
Supplementary Table 6 from Novel Candidate Cancer Genes Identified by a Large-Scale Cross-Species Comparative Oncogenomics Approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2289d578fc1d7b63139101d1d03793e
https://doi.org/10.1158/0008-5472.22386599
https://doi.org/10.1158/0008-5472.22386599
Autor:
Maarten van Lohuizen, Anton Berns, Lodewyk Wessels, David J. Adams, Jane Rogers, Jos Jonkers, Anders H. Lund, Jack Lenz, Colin Pritchard, Jules Gadiot, Paul Krimpenfort, Wendy Lagcher, Konstantin Matentzoglu, Miranda van Uitert, Geoffrey Turner, Jeroen de Ridder, Daoud Sie, Carla P. Martins, Anthony G. Uren, Jaap Kool
Supplementary Table 4 from Insertional Mutagenesis in Mice Deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 Reveals Cancer Gene Interactions and Correlations with Tumor Phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b00b83e5583745650bd7a3120fdfdc
https://doi.org/10.1158/0008-5472.22385417.v1
https://doi.org/10.1158/0008-5472.22385417.v1
Autor:
Maarten van Lohuizen, Anton Berns, Lodewyk Wessels, David J. Adams, Jane Rogers, Jos Jonkers, Anders H. Lund, Jack Lenz, Colin Pritchard, Jules Gadiot, Paul Krimpenfort, Wendy Lagcher, Konstantin Matentzoglu, Miranda van Uitert, Geoffrey Turner, Jeroen de Ridder, Daoud Sie, Carla P. Martins, Anthony G. Uren, Jaap Kool
Supplementary Figure 2 from Insertional Mutagenesis in Mice Deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 Reveals Cancer Gene Interactions and Correlations with Tumor Phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828a4428ebfc883c1e08923d3e13bc35
https://doi.org/10.1158/0008-5472.22385441
https://doi.org/10.1158/0008-5472.22385441
Autor:
David J. Adams, Tim Hubbard, Lara S. Collier, Anton Berns, Maarten van Lohuizen, P. Andy Futreal, Michael R. Stratton, David A. Largaespada, Louise van der Weyden, Catherine H. Wilson, Markus Brosch, Alistair G. Rust, Adam Butler, Graham R. Bignell, Jos Jonkers, Lodewyk Wessels, Jeroen de Ridder, Anthony G. Uren, Jaap Kool, Jenny Mattison
Comparative genomic hybridization (CGH) can reveal important disease genes but the large regions identified could sometimes contain hundreds of genes. Here we combine high-resolution CGH analysis of 598 human cancer cell lines with insertion sites is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559c580e0196c98d38f7d71fd3dbe244
https://doi.org/10.1158/0008-5472.c.6501584.v1
https://doi.org/10.1158/0008-5472.c.6501584.v1
Autor:
Maarten van Lohuizen, Anton Berns, Lodewyk Wessels, David J. Adams, Jane Rogers, Jos Jonkers, Anders H. Lund, Jack Lenz, Colin Pritchard, Jules Gadiot, Paul Krimpenfort, Wendy Lagcher, Konstantin Matentzoglu, Miranda van Uitert, Geoffrey Turner, Jeroen de Ridder, Daoud Sie, Carla P. Martins, Anthony G. Uren, Jaap Kool
Supplementary Table 7 from Insertional Mutagenesis in Mice Deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 Reveals Cancer Gene Interactions and Correlations with Tumor Phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9e76141a8cdb8e64cc759b4cc5b283
https://doi.org/10.1158/0008-5472.22385408.v1
https://doi.org/10.1158/0008-5472.22385408.v1
Autor:
Maarten van Lohuizen, Anton Berns, Lodewyk Wessels, David J. Adams, Jane Rogers, Jos Jonkers, Anders H. Lund, Jack Lenz, Colin Pritchard, Jules Gadiot, Paul Krimpenfort, Wendy Lagcher, Konstantin Matentzoglu, Miranda van Uitert, Geoffrey Turner, Jeroen de Ridder, Daoud Sie, Carla P. Martins, Anthony G. Uren, Jaap Kool
Supplementary Table 8 from Insertional Mutagenesis in Mice Deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 Reveals Cancer Gene Interactions and Correlations with Tumor Phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396750dab3be990e3136dcda58740949
https://doi.org/10.1158/0008-5472.22385405
https://doi.org/10.1158/0008-5472.22385405