Zobrazeno 1 - 10
of 313
pro vyhledávání: '"G. Ulrich Nienhaus"'
Autor:
Daniel Englert, Eva-Maria Burger, Franziska Grün, Mrigank S. Verma, Jens Lackner, Marko Lampe, Bastian Bühler, Janin Schokolowski, G. Ulrich Nienhaus, Andres Jäschke, Murat Sunbul
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Live-cell RNA imaging with high spatial and temporal resolution remains a major challenge. Here we report the development of RhoBAST:SpyRho, a fluorescent light-up aptamer (FLAP) system ideally suited for visualizing RNAs in live or fixed ce
Externí odkaz:
https://doaj.org/article/9497349644eb460a9fa92b4db02b0bfb
Autor:
Nane C. Kuznik, Valeria Solozobova, Irene I. Lee, Nicole Jung, Linxiao Yang, Karin Nienhaus, Emmanuel A. Ntim, Jaice T. Rottenberg, Claudia Muhle-Goll, Amrish Rajendra Kumar, Ravindra Peravali, Simone Gräßle, Victor Gourain, Célia Deville, Laura Cato, Antje Neeb, Marco Dilger, Christina A. Cramer von Clausbruch, Carsten Weiss, Bruno Kieffer, G. Ulrich Nienhaus, Myles Brown, Stefan Bräse, Andrew C.B. Cato
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104175- (2022)
Summary: BAG1 is a family of polypeptides with a conserved C-terminal BAG domain that functions as a nucleotide exchange factor for the molecular chaperone HSP70. BAG1 proteins also control several signaling processes including proteostasis, apoptosi
Externí odkaz:
https://doaj.org/article/ef7d174a265a47ad8c77177cd0835a85
Autor:
Karin Nienhaus, G. Ulrich Nienhaus
Publikováno v:
Frontiers in Molecular Biosciences, Vol 4 (2018)
The human heme enzymes tryptophan 2,3-dioxygenase (hTDO) and indoleamine 2,3 dioxygenase (hIDO) catalyze the initial step in L-tryptophan (L-Trp) catabolism, the insertion of dioxygen into L-Trp. Overexpression of these enzymes causes depletion of L-
Externí odkaz:
https://doaj.org/article/26a0bcd950074c4e8de5d1c424a54f2a
Autor:
Cornelia Loos, Tatiana Syrovets, Anna Musyanovych, Volker Mailänder, Katharina Landfester, G. Ulrich Nienhaus, Thomas Simmet
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 5, Iss 1, Pp 2403-2412 (2014)
Nanoparticles of various shapes, sizes, and materials carrying different surface modifications have numerous technological and biomedical applications. Yet, the mechanisms by which nanoparticles interact with biological structures as well as their bi
Externí odkaz:
https://doaj.org/article/a7214c67e2414bc8a5ef341062e755c8
Autor:
Li Shang, Karin Nienhaus, Xiue Jiang, Linxiao Yang, Katharina Landfester, Volker Mailänder, Thomas Simmet, G. Ulrich Nienhaus
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 5, Iss 1, Pp 2388-2397 (2014)
Engineered nanomaterials are known to enter human cells, often via active endocytosis. Mechanistic details of the interactions between nanoparticles (NPs) with cells are still not well enough understood. NP size is a key parameter that controls the e
Externí odkaz:
https://doaj.org/article/d030bfc0ba5b4fa0bb0703f375a68dc1
Autor:
Li Shang, G. Ulrich Nienhaus
Publikováno v:
APL Materials, Vol 5, Iss 5, Pp 053101-053101-7 (2017)
Metal nanoclusters (NCs), a new type of nanomaterial with unique physicochemical properties, show great potential in many biomedical applications. Understanding their behavior in the complex biological environment is critical not only for designing h
Externí odkaz:
https://doaj.org/article/6a44566fe5f04af2b5cc34e9069582dd
Autor:
Pauline Maffre, Stefan Brandholt, Karin Nienhaus, Li Shang, Wolfgang J. Parak, G. Ulrich Nienhaus
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 5, Iss 1, Pp 2036-2047 (2014)
By using fluorescence correlation spectroscopy (FCS), we have studied the adsorption of human serum albumin (HSA) onto Fe–Pt nanoparticles (NPs, 6 nm radius), CdSe/ZnS quantum dots (QDs, 5 nm radius) and Au and Ag nanoclusters (1–4 nm radius), wh
Externí odkaz:
https://doaj.org/article/c25676f8ae9044b082e673eb4fd23c18
In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?
Autor:
Moritz Nazarenus, Qian Zhang, Mahmoud G. Soliman, Pablo del Pino, Beatriz Pelaz, Susana Carregal-Romero, Joanna Rejman, Barbara Rothen-Rutishauser, Martin J. D. Clift, Reinhard Zellner, G. Ulrich Nienhaus, James B. Delehanty, Igor L. Medintz, Wolfgang J. Parak
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 5, Iss 1, Pp 1477-1490 (2014)
The interfacing of colloidal nanoparticles with mammalian cells is now well into its second decade. In this review our goal is to highlight the more generally accepted concepts that we have gleaned from nearly twenty years of research. While details
Externí odkaz:
https://doaj.org/article/da8f14a590744b4ba7defa57c8072501
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 2, Iss 1, Pp 374-383 (2011)
Using dual-focus fluorescence correlation spectroscopy, we have analyzed the adsorption of three human blood serum proteins, namely serum albumin, apolipoprotein A-I and apolipoprotein E4, onto polymer-coated, fluorescently labeled FePt nanoparticles
Externí odkaz:
https://doaj.org/article/29f1f9673f054139aa172b40340f912f
Autor:
Bernd Jahrsdörfer, Hubert Schrezenmeier, Peter Möller, Rolf Kreienberg, Thomas Simmet, G. Ulrich Nienhaus, Oleg Lunov, Ramin Lotfi, Dorit Fabricius, Frank Reister, Thamara Beyer, Thomas F.E. Barth, Christof Kaltenmeier, Magdalena Hagn, Kai Sontheimer, Karen Dahlke, Stefanie Lindner
PDF file - 182K, Supplemental Figure 1. B cells activated with IL-21 and anti-BCR secrete enzymatically active granzyme B. Supplemental Figure 2. Interleukin 21 in the absence of B cells does not suppress T cell proliferation. Supplemental Figure 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e0bf137b5ad341824f146517ce1bf2
https://doi.org/10.1158/0008-5472.22399989.v1
https://doi.org/10.1158/0008-5472.22399989.v1
