Zobrazeno 1 - 10
of 254
pro vyhledávání: '"G. Tunnicliff"'
Autor:
B. U. Raess, G. Tunnicliff
'After being frequently urged to write upon this subject, and as often declining to do it, from apprehension of my own inability, I am at length compelled to take up the pen, however unqualified I may still feel myself for the task.'William Withering
Autor:
G. J. Crites, G. Tunnicliff
Publikováno v:
IUBMB Life. 46:43-54
The effects of three potential irreversible inhibitors of gamma-aminobutyrate aminotransferase from Pseudomonas fluorescens were studied in order to throw more light on the nature of the active site of the enzyme. The thiol group reagent mercuric chl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ded1b621d2ff3b3fc5171e0d43e173b
https://doi.org/10.1080/15216549800203542
https://doi.org/10.1080/15216549800203542
Autor:
Sara J. McCormick, G. Tunnicliff
Publikováno v:
Pharmacology. 57:124-131
Synaptosomes prepared from mouse brain possess a Na+-dependent transport system for γ-hydroxybutyrate displaying saturation kinetics, the transport constant (Kt) for which was calculated as 31 ± 9 µmol/l. Several γ-hydroxybutyrate and γ-aminobut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769a6c265d65c29123e543c85a1a4e41
https://doi.org/10.1159/000028233
https://doi.org/10.1159/000028233
Publikováno v:
Canadian Journal of Zoology. 74:688-692
In humans, glycine enters the red cell via four distinct plasma membrane carrier systems. The purpose of the present experiments was to measure the mode of transport of glycine by channel catfish (Ictalurus punctatus) red cells. About 54% of the glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f5e9a72a1bc614460cb75281799ebd8
https://doi.org/10.1139/z96-077
https://doi.org/10.1139/z96-077
Autor:
G. Tunnicliff
Publikováno v:
Journal of Enzyme Inhibition. 9:309-316
4-Aminobutyrate aminotransferase (EC 2.6.1.19), obtained from Pseudomonas fluorescens, was irreversibly inhibited by phenylglyoxal, a reagent that specifically modifies arginyl residues. The inactivation appeared to be the result of a simple, bimolec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2444e1764d9c1d44798d4d0491c19eb7
https://doi.org/10.3109/14756369509036560
https://doi.org/10.3109/14756369509036560
Autor:
G. Tunnicliff
Publikováno v:
Comparative Biochemistry and Physiology Part A: Physiology. 108:471-478
The human erythrocyte plasma membrane is permeable to several free amino acids usually present in the bloodstream. Seven distinct routes of entry have been described which represent both secondary active transport and facilitated diffusion (passive t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b4caeecfccedbee36482cc102036ea
https://doi.org/10.1016/0300-9629(94)90329-8
https://doi.org/10.1016/0300-9629(94)90329-8
Autor:
G. Tunnicliff
Publikováno v:
Pharmacology. 49:271-277
A synaptosomal preparation from mouse brain transported γ-hydroxybutyric acid in a manner displaying saturation kinetics. A Kt of 48 ± 11 µ M was calculated. In the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c37a364708318eeae255062cbe9137e9
https://doi.org/10.1159/000139243
https://doi.org/10.1159/000139243
Autor:
C D Cash, G Tunnicliff
Publikováno v:
Gamma-Hydroxybutyrate: Molecular, functional and clinical aspects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb3623a0a5d5f4c44212dfd5c0636be9
https://doi.org/10.4324/9780203300992_chapter_2
https://doi.org/10.4324/9780203300992_chapter_2
Autor:
G Tunnicliff
Publikováno v:
Gamma-Hydroxybutyrate: Molecular, functional and clinical aspects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52b0f9cd0b90527a87374edd9f45e568
https://doi.org/10.4324/9780203300992_chapter_4
https://doi.org/10.4324/9780203300992_chapter_4
Autor:
G, Tunnicliff, E, Malatynska
Publikováno v:
Neurochemical research. 28(6)
Clinical depression and other mood disorders are relatively common mental illnesses but therapy for a substantial number of patients is unsatisfactory. For many years clinicians and neuroscientists believed that the evidence pointed toward alteration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::266fbb513adf272a6d0587593ef54386
https://pubmed.ncbi.nlm.nih.gov/12718451
https://pubmed.ncbi.nlm.nih.gov/12718451