Zobrazeno 1 - 10
of 209
pro vyhledávání: '"G. Taucher"'
Autor:
G. Taucher-Scholz, Sebastian Zahnreich, Claudia Fournier, Till Dettmering, Marco Durante, Miriam Colindres-Rojas
Publikováno v:
Journal of Radiation Research
The production of reactive oxygen species (ROS), especially superoxide anions (O2 (·-)), is enhanced in many normal and tumor cell types in response to ionizing radiation. The influence of ionizing radiation on the regulation of ROS production is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fd9fea9952bf8ba6b8d04a06ca50fc
http://europepmc.org/articles/PMC4572590
http://europepmc.org/articles/PMC4572590
Autor:
G. Taucher-Scholz, B. Jakob
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 245:292-297
Ion beams offer the possibility to generate strictly localized DNA lesions within subregions of a cell nucleus. The distribution of the ion-induced damage can be indirectly visualized by immunocytochemical detection of repair-related proteins as radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfec94837b1fe348b44b29f44e8c1a72
https://doi.org/10.1016/j.nimb.2005.11.117
https://doi.org/10.1016/j.nimb.2005.11.117
Publikováno v:
Radiation Research. 163:681-690
To study the dynamics of protein recruitment to DNA lesions, ion beams can be used to generate extremely localized DNA damage within restricted regions of the nuclei. This inhomogeneous spatial distribution of lesions can be visualized indirectly and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46464df41d3bf30d6b3a5f58ee46cc13
https://doi.org/10.1667/rr3374
https://doi.org/10.1667/rr3374
Publikováno v:
Journal of Physics: Condensed Matter. 17:S1443-S1446
According to the experimental evidence damage induced by densely ionizing radiation in chromosomes and DNA molecules is distributed in the form of clusters. The most critical type of DNA damage is double-strand breaks (DSBs) which are formed when bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2506424f6ef8d58ca1cc9b3d086dcbce
https://doi.org/10.1088/0953-8984/17/18/002
https://doi.org/10.1088/0953-8984/17/18/002
Autor:
G. Taucher-Scholz, J. Splinter, Ken Ichi Yano, Burkhard Jakob, Marco Durante, Marion C. Lang, Stefan W. Hell, David J. Chen, Johann Engelhardt
Publikováno v:
Mutagenesis
The induction of localized DNA damage within a discrete nuclear volume is an important tool in DNA repair studies. Both charged particle irradiation and laser microirradiation (LMI) systems allow for such a localized damage induction, but the results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b949597418203b11fa212fe7793c0a
http://hdl.handle.net/11588/506306
http://hdl.handle.net/11588/506306
Akademický článek
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Autor:
Reinhard Neumann, G. Taucher-Scholz, Ewa Gudowska-Nowak, Katarzyna Psonka, Stephan Brons, Markus Heiß
Publikováno v:
Radiotherapy and Oncology. 73:S112-S114
Atomic Force Microscopy of phiX174 plasmids irradiated in vitro was used to visualise the DNA fragmentation induced by heavy ions and to compare it to the fragmentation pattern obtained after X-irradiation. Fragment distributions induced by low ion f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c78c101b897b1e4d8ea426d8afb1c7e
https://doi.org/10.1016/s0167-8140(04)80029-x
https://doi.org/10.1016/s0167-8140(04)80029-x
Autor:
Cheng Peng, Peter J. McKinnon, Junjie Chen, G. Taucher-Scholz, Martin F. Lavin, Markus Fusser, Sachin Katyal, Olivier J. Becherel, Bernd Epe, Burkhard Jakob, Nuri Gueven, Amanda W. Kijas, Stephen J. Smerdon, A.L. Cherry
Publikováno v:
Nucleic Acids Research
Print: 0305-1048
Print: 0305-1048
Aprataxin, defective in the neurodegenerative disorder ataxia oculomotor apraxia type 1, resolves abortive DNA ligation intermediates during DNA repair. Here, we demonstrate that aprataxin localizes at sites of DNA damage induced by high LET radiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e7b5e7773664f333e876d3e2a8ed3e
https://pubmed.ncbi.nlm.nih.gov/20008512
https://pubmed.ncbi.nlm.nih.gov/20008512
Publikováno v:
Radiation research. 171(4)
Irradiation of cell nuclei with charged particles leads to the spatially defined production of DNA damage along the particle trajectories, thus facilitating studies on the dynamics of radiation-induced protein foci associated with lesion processing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8764b4fd2a83efe345925000dc87cb
https://pubmed.ncbi.nlm.nih.gov/19397441
https://pubmed.ncbi.nlm.nih.gov/19397441