Zobrazeno 1 - 10
of 150
pro vyhledávání: '"G. T. SHIRES"'
The Role of Tumor Necrosis Factor and Nitric Oxide in the Acute Cardiovascular Response to Endotoxin
Publikováno v:
Annals of Surgery. 223:63-69
OBJECTIVE: This study was designed to examine the differential effects of tumor necrosis factor (TNF) and nitric oxide on the acute cardiovascular changes that occur in response to endotoxemia. SUMMARY BACKGROUND DATA: Recent studies have suggested t
Publikováno v:
The Journal of Trauma: Injury, Infection, and Critical Care. 33:561-567
Cyclo-oxygenase metabolites are important regulators of pulmonary vascular and airway tone and may act to regulate ventilation-perfusion (VA/Q) relationships. Hypoxemia that follows aspiration of gastric acid is associated with increased venous admix
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 261:H1190-H1196
Gut barrier failure and bacterial translocation (BT) after thermal injury may result from splanchnic vasoconstriction and intestinal ischemia. The role of the renin-angiotensin system in intestinal blood flow and BT after thermal injury was studied b
Increased Neutrophil Mobilization and Decreased Chemotaxis During Cortisol and Epinephrine Infusions
Autor:
Kevin J. Tracy, Stephen F. Lowry, John Mihran Davis, G T Shires, Roger W. Yurt, J. D. Albert, Steve E. Calvano
Publikováno v:
The Journal of Trauma: Injury, Infection, and Critical Care. 31:725-732
Although hormones are putative mediators of neutrophil changes after injury, the effects of trauma-induced levels of plasma cortisol and epinephrine on circulating neutrophils have not been reported in humans. The dynamics of PMN mobilization and che
Publikováno v:
Annals of Surgery. 212:567-580
While monitoring blood pressure is a routine part of intraoperative management, several methods have been proposed to characterize intraoperative hemodynamic patterns as predictors of postoperative complications. In this prospective study of a high-r
Autor:
Stephen F. Lowry, A. E. Barber, Joseph P. Minei, J. L. Rayburn, G. T. Shires, C. V. Keogh, Thomas J. Fahey, L. L. Moldawer, William G. Jones, E. Fischer
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 14:335-343
Despite provision of adequate calories, defined formula diets in rats lead to bacterial translocation (BT), fatty infiltration of the liver, and an increased susceptibility to endotoxin. These deleterious effects may be due in part to a loss of intes
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 258:R684-R689
The increase in intracellular Na+ concentration ([ Na+]i) and H2O content and decrease in K+ concentration during hemorrhagic shock have been observed. However, the state of the increased [Na+]i has never been defined. In this investigation double-ba
Publikováno v:
Surgery. 124(3)
Attempts to modify traditional fluid resuscitation have been based on animal models that evaluate several variables including anesthesia. This study presents the effects of early saline resuscitation from severe uncontrolled hemorrhage unanesthetized
Publikováno v:
The American surgeon. 63(5)
Laparoscopic fundoplication is technically feasible in treating gastroesophageal reflux disease (GERD). Although medication is the primary treatment for GERD, not all patients respond completely or are able to adhere to a medical regimen. In the pres
Autor:
A E, Barber, G T, Shires
Publikováno v:
New horizons (Baltimore, Md.). 4(2)
Hypoperfusion of tissue results in cell membrane dysfunction. Normally, the cell membrane serves to preserve the milieu interior through the maintenance of a negative charge or membrane potential. Maintenance of a negative membrane potential across t