Zobrazeno 1 - 10
of 20
pro vyhledávání: '"G. T. Merlino"'
Autor:
I. Pastan, Hanan Galski, Mark C. Willingham, G. T. Merlino, Michael M. Gottesman, Gerald H. Mickisch
Publikováno v:
Aktuelle Urologie. 22:85-91
Autor:
S J Brand, EV Schmidt, PS Oates, Susan Bonner-Weir, G T Merlino, B Simon, M Chulak, Timothy C. Wang
Gastrin is transiently expressed in fetal islets during a critical period of their development from protodifferentiated islet precursors in fetal pancreatic ducts. To examine the possible role of gastrin as an islet cell growth factor, postnatal isle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d82d35af26c13c10ef7455ea59c87a
https://europepmc.org/articles/PMC288276/
https://europepmc.org/articles/PMC288276/
Publikováno v:
Cancer research. 51(19)
A common form of multidrug resistance in human cancer results from expression of the MDR1 gene which encodes a plasma membrane energy-dependent multidrug efflux pump. We have engineered transgenic mice which express this multidrug transporter in thei
Publikováno v:
Biotechnology (Reading, Mass.). 16
Autor:
R, Kageyama, G T, Merlino
Publikováno v:
Methods in enzymology. 198
Autor:
G T, Merlino
Publikováno v:
Seminars in cancer biology. 1(4)
The epidermal growth factor (EGF) receptor is a transmembrane, cell-surface glycoprotein that mediates the mitogenic action of a family of ligands, including EGF and transforming growth factor alpha (TGF alpha). Perturbation of this signal transducti
Publikováno v:
Regulatory Peptides. 40:275
Autor:
G T Merlino, S Ishii, J Whang-Peng, T Knutsen, Y H Xu, A J Clark, R H Stratton, R K Wilson, D P Ma, B A Roe, J H Hunts, N Shimizu, I Pastan
Publikováno v:
Molecular and Cellular Biology. 5:1722-1734
A431 cells have an amplification of the epidermal growth factor (EGF) receptor gene, the cellular homolog of the v-erb B oncogene, and overproduce an aberrant 2.9-kilobase RNA that encodes a portion of the EGF receptor. A cDNA (pE15) for the aberrant
Publikováno v:
Journal of Biological Chemistry. 264:5488-5494
Two separate enhancers were identified both upstream and downstream of the promoter of the human epidermal growth factor receptor gene. Transcriptional enhancer activity was found to be associated with a region 1172 and 852 base pairs upstream of the
Publikováno v:
Molecular and Cellular Biology. 9:4357-4363
The human multidrug resistance gene (MDR1) encodes a drug efflux pump glycoprotein (P-glycoprotein) responsible for resistance to multiple cytotoxic drugs. A plasmid carrying a human MDR1 cDNA under the control of a chicken beta-actin promoter was us