Zobrazeno 1 - 10
of 40
pro vyhledávání: '"G. T. Macfarlane"'
Autor:
J. H. Cummings, G. T. Macfarlane
Publikováno v:
British Journal of Nutrition. 87:S145-S151
The defining effect of prebiotics is to stimulate selectively the growth of bifidobacteria and lactobacilli in the gut and, thereby, increase the body's natural resistance to invading pathogens. Prebiotic carbohydrates may also have additional, less
Publikováno v:
Gut. 48:198-205
BACKGROUND—The normal intestinal microflora plays an important role in host metabolism and provides a natural defence mechanism against invading pathogens. Although the microbiota in adults has been extensively studied, little is known of the chang
Publikováno v:
Journal of Applied Microbiology. 85:372-380
Ecological and physiological effects of the sulphate-reducing bacterium (SRB) Desulfovibrio desulfuricans on other intestinal organisms were investigated in anaerobic chemostats (dilution rate approximately 0.2 h-1). Reproducible defined bacterial co
Publikováno v:
FEMS Microbiology Ecology. 26:231-243
Human faecal microorganisms were grown on mixtures of chemically diverse polymerised C-sources (starch, pectin, xylan, mucin, arabinogalactan, inulin, guar gum) in a three-stage continuous culture model of the colon. The effects of retention time (R=
Autor:
G. T. Macfarlane, E.A Smith
Publikováno v:
FEMS Microbiology Ecology. 25:355-368
Proteins and trichloroacetic acid-soluble peptides were present in high concentrations in human intestinal contents and faeces. Free amino acids were also detected in millimolar amounts in proximal and distal colon contents, with hydroxyproline, alan
Autor:
Sandra Macfarlane, G. T. Macfarlane
Publikováno v:
Journal of Medical Microbiology. 46:547-555
Bacteroides splanchnicus in common with several members of the B. fragilis group constitutively produced a number of protein and peptide hydrolysing enzymes. Amongst the most active was an arylamidase, which specifically hydrolysed the dipeptidyl chr
Publikováno v:
Scopus-Elsevier
The human colonic ecosystem is an extremely complex environment comprised of several hundred different strains of bacteria. Studies were undertaken to determine whether these organisms formed metabolic or genotypically distinct assemblages in the gut
Autor:
Andrew J. McBain, G. T. Macfarlane
Publikováno v:
Scandinavian Journal of Gastroenterology. 32:32-40
Several different types of in vitro fermentation systems are currently employed to investigate pro- and prebiotic activities in the human large intestinal microbiota, ranging from simple batch cultures, with or without stirring and pH control, to mor
Autor:
C Hoebler, Corinne Rumney, Ian Rowland, I Nordgaard, J.-L. Barry, G T Macfarlane, S Macfarlane, K A Reed, John C. Mathers, P B Mortensen
Publikováno v:
British Journal of Nutrition. 74:303-322
Five European laboratories tested a simplein vitrobatch system for dietary fibre fermentation studies. The inoculum was composed of fresh human faeces mixed with a carbonate-phosphate buffer complex supplemented with trace elements and urea. Five die
Publikováno v:
Microbial Ecology in Health and Disease; Vol 12, No 2 (2000)
The large intestinal microbiota is characteristically viewed as being a homogeneous entity, yet the proximal colon and distal bowel differ markedly in relation to their nutritional availabilities and physicochemical attributes. Moreover, individual s