Trojan‐Horse Strategy Targeting the Gut‐Liver Axis Modulates Gut Microbiome and Reshapes Microenvironment for Orthotopic Hepatocellular Carcinoma Therapy.

Autor: Yao, Haochen^1,2 (AUTHOR), Ma, Sheng^3,4 (AUTHOR) nealma@ciac.ac.cn, Huang, Juanjuan^2,5 (AUTHOR), Si, Xinghui^3,4 (AUTHOR), Yang, Ming⁶ (AUTHOR), Song, Wantong^3,4 (AUTHOR), Lv, Guoyue¹ (AUTHOR) lvgy@jlu.edu.cn, Wang, Guoqing² (AUTHOR) qing@jlu.edu.cn

Publikováno v: Advanced Science. Nov2024, Vol. 11 Issue 44, p1-14. 14p.

Leveraging Organ-on-Chip Models to Investigate Host-Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease.

Autor: Kaden T; Dynamic42 GmbH, 07745, Jena, Germany.; Institute of Biochemistry II, Center for Sepsis Control and Care, Jena University Hospital, 07747, Jena, Germany., Alonso-Román R; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, 07745, Jena, Germany.; Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, 07745, Jena, Germany., Stallhofer J; Department of Internal Medicine IV, Jena University Hospital, 07747, Jena, Germany., Gresnigt MS; Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, 07745, Jena, Germany.; Junior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, 07745, Jena, Germany., Hube B; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, 07745, Jena, Germany.; Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, 07745, Jena, Germany.; Institute of Microbiology, Faculty of Biological Sciences, Friedrich Schiller University, 07743, Jena, Germany., Mosig AS; Institute of Biochemistry II, Center for Sepsis Control and Care, Jena University Hospital, 07747, Jena, Germany.; Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, 07745, Jena, Germany.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2024 Nov 03, pp. e2402756. Date of Electronic Publication: 2024 Nov 03.

Growth of a human intestinal Desulfovibrio desulfuricans in continuous cultures containing defined populations of saccharolytic and amino acid fermenting bacteria

Autor: G. T. Macfarlane, D F Newton, S. Macfarlane, John H. Cummings

Publikováno v: Journal of Applied Microbiology. 85:372-380

Ecological and physiological effects of the sulphate-reducing bacterium (SRB) Desulfovibrio desulfuricans on other intestinal organisms were investigated in anaerobic chemostats (dilution rate approximately 0.2 h-1). Reproducible defined bacterial co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f7953646c2ea8200fec9af3c333fb9
https://doi.org/10.1046/j.1365-2672.1998.00522.x

Enumeration of amino acid fermenting bacteria in the human large intestine: effects of pH and starch on peptide metabolism and dissimilation of amino acids

Autor: G. T. Macfarlane, E.A Smith

Publikováno v: FEMS Microbiology Ecology. 25:355-368

Proteins and trichloroacetic acid-soluble peptides were present in high concentrations in human intestinal contents and faeces. Free amino acids were also detected in millimolar amounts in proximal and distal colon contents, with hydroxyproline, alan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b69421d9f7027237dff0257e8c98befe
https://doi.org/10.1111/j.1574-6941.1998.tb00487.x

Consequences of Biofilm and Sessile Growth in the Large Intestine

Autor: Andrew J. McBain, S. Macfarlane, G. T. Macfarlane

Publikováno v: Scopus-Elsevier

The human colonic ecosystem is an extremely complex environment comprised of several hundred different strains of bacteria. Studies were undertaken to determine whether these organisms formed metabolic or genotypically distinct assemblages in the gut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79151ddf65fed92f6e45fdab3845de3
https://doi.org/10.1177/08959374970110011801