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pro vyhledávání: '"G. T. Hermanson"'
Autor:
G. T. Hermanson, F. L. van Delft
Publikováno v:
Chemical Linkers in Antibody–Drug Conjugates (ADCs) ISBN: 9781839162633
A key quality attribute of any ADC is the mode of attachment of the linker-drug to the monoclonal antibody. Early generation technologies were based exclusively on one of two approaches, i.e. covalent bond formation with – abundantly available –
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fec573b35acc7d098a165cffd9268c13
https://doi.org/10.1039/9781839165153-00032
https://doi.org/10.1039/9781839165153-00032
Publikováno v:
Chemical Linkers in Antibody–Drug Conjugates (ADCs) ISBN: 9781839162633
Uniform polyethylene glycol (PEG) linkers and spacers have proven to be critical components for modifying and mediating the properties of antibody–drug conjugates (ADCs). These short, flexible, amphiphilic compounds lack polymeric dispersity and ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb94fa49e45f410c5d8c6e244b4b2b55
https://doi.org/10.1039/9781839165153-00286
https://doi.org/10.1039/9781839165153-00286
Publikováno v:
American biotechnology laboratory. 12(10)
Autor:
D C, Klenk, G T, Hermanson, R I, Krohn, E K, Fujimoto, A K, Mallia, P K, Smith, J D, England, H M, Wiedmeyer, R R, Little, D E, Goldstein
Publikováno v:
Clinical chemistry. 28(10)
An affinity-chromatographic method for determination of glycosylated hemoglobin (Anal. Lett. 14: 649-661, 1981) is compared with the thiobarbituric acid colorimetric (I) (Clin. Chem. 27: 669-672, 1981) and the ion-exchange liquid-chromatographic (II)