Zobrazeno 1 - 10
of 809
pro vyhledávání: '"G. Swain"'
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 7, Pp 965-972 (2024)
Background and Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common cause of chronic liver disease worldwide. The current and projected cost of treating individuals with MASLD in Canada remains unknown. Our object
Externí odkaz:
https://doaj.org/article/fe97c37ff3674f83b9d3d8d92077cf2b
Autor:
Adam Amlani, May Y. Choi, Katherine A. Buhler, Marie Hudson, Mark Tarnopolsky, Lauren Brady, Heinrike Schmeling, Mark G. Swain, Cory Stingl, Ann Reed, Marvin J. Fritzler
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 1, Pp 10-14 (2023)
Objective The rationale for this study was based on reports that valosin‐containing protein (VCP) mutations are found in hereditary inclusion body myositis (IBM) and VCP was detected in rimmed vacuoles of sporadic IBM (sIBM) muscle biopsies. Autoan
Externí odkaz:
https://doaj.org/article/c574cec2f45344ab9220dd01f3da2ef2
Autor:
Henry H. Nguyen, Mark G. Swain
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Symptoms of fatigue, social withdrawal and mood disturbances are commonly encountered in patients with chronic liver disease and have a detrimental effect on patient quality of life. Treatment options for these symptoms are limited and a current area
Externí odkaz:
https://doaj.org/article/5c272cfdab3c4cee82a42151cc38dc4c
Autor:
Nina L. Cluny, Kewir D. Nyuyki, Wagdi Almishri, Lateece Griffin, Benjamin H. Lee, Simon A. Hirota, Quentin J. Pittman, Mark G. Swain, Keith A. Sharkey
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background Behavioral comorbidities, such as anxiety and depression, are a prominent feature of IBD. The signals from the inflamed gut that cause changes in the brain leading to these behavioral comorbidities remain to be fully elucidated. W
Externí odkaz:
https://doaj.org/article/ef43bce9d5ca482a970897fdee876d16
Publikováno v:
Hepatology Communications, Vol 7, Iss 3, Pp e0036-e0036 (2023)
NASH is a potentially progressive form of NAFLD characterized by hepatocyte injury and liver inflammation which can cause fibrosis. Currently, there are limited data on the patient experience of NASH. Our aim was to use both literature review and pat
Externí odkaz:
https://doaj.org/article/5ebe9184fc1b4f9ba9650e617e113fb8
Publikováno v:
Hepatology Communications, Vol 7, Iss 3, Pp e0062-e0062 (2023)
Background:. Depression is common in patients with chronic viral hepatitis. We evaluated the impact of major depressive disorder (MDD) and antidepressant use on survival among patients with HBV and HCV. Methods:. We used The Health Improvement Networ
Externí odkaz:
https://doaj.org/article/0ec8fd5352e24214bbf8bf3712e129fd
Autor:
David Jones, Marco Carbone, Pietro Invernizzi, Nicola Little, Frederik Nevens, Mark G. Swain, Philippe Wiesel, Cynthia Levy
Publikováno v:
Hepatology Communications, Vol 7, Iss 3, Pp e0057-e0057 (2023)
Background:. There is a real unmet need for primary biliary cholangitis (PBC) treatments that can improve quality of life impacting symptoms. In this post hoc analysis, we evaluated potential effects of the NADP oxidase 1/4 inhibitor, setanaxib, on p
Externí odkaz:
https://doaj.org/article/9ce47b2b75e34bd29cbbba9a3594d8eb
Autor:
Shivali S. Joshi, Rachelle P. Davis, Mang M. Ma, Edward Tam, Curtis L. Cooper, Alnoor Ramji, Erin M. Kelly, Saumya Jayakumar, Mark G. Swain, Craig N. Jenne, Carla S. Coffin
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Obesity and cirrhosis are associated with poor hepatitis B virus (HBV) vaccine responses, but vaccine efficacy has not been assessed in nonalcoholic fatty liver disease (NAFLD). Sixty-eight HBV-naïve adults with NAFLD were enrolled through
Externí odkaz:
https://doaj.org/article/d4dddf359a0648d181b13bb455e83642
Autor:
Surain B. Roberts, Marwa Ismail, Gowthami Kanagalingam, Andrew L. Mason, Mark G. Swain, Catherine Vincent, Eric M. Yoshida, Cynthia Tsien, Jennifer A. Flemming, Harry L.A. Janssen, Gideon M. Hirschfield, Bettina E. Hansen, Aliya F. Gulamhusein, the Canadian Network for Autoimmune Liver Disease
Publikováno v:
Hepatology Communications, Vol 4, Iss 9, Pp 1332-1345 (2020)
Patients with primary biliary cholangitis (PBC) with incomplete response to ursodeoxycholic acid are at risk of disease progression and need additional therapy. Obeticholic acid (OCA) was approved in Canada in May 2017, but its effectiveness in a rea
Externí odkaz:
https://doaj.org/article/0b61f127e4ca4dbfb8963ff2a0226bb9
Autor:
Wagdi Almishri, Rachelle P. Davis, Abdel-Aziz Shaheen, Mohammed O. Altonsy, Craig N. Jenne, Mark G. Swain
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionB cells are important regulators of both adaptive and innate immunity. The normal liver contains significant numbers of B cells, and their numbers increase dramatically in immune-mediated liver diseases. Our previous observations suggest
Externí odkaz:
https://doaj.org/article/7c2cfff06b0d4cb4a31244b56b0e20a7