Zobrazeno 1 - 10
of 244
pro vyhledávání: '"G. Stopa"'
Publikováno v:
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-10 (2018)
Abstract Background The roles of the choroid plexus (CP) and cerebrospinal fluid (CSF) production have drawn increasing attention in Alzheimer’s disease (AD) research. Specifically, studies document markedly decreased CSF production and turnover in
Externí odkaz:
https://doaj.org/article/39f4f2b1f09945a1a97f0c145a105e11
Autor:
Edward G. Stopa, Keith Q. Tanis, Miles C. Miller, Elena V. Nikonova, Alexei A. Podtelezhnikov, Eva M. Finney, David J. Stone, Luiz M. Camargo, Lisan Parker, Ajay Verma, Andrew Baird, John E. Donahue, Tara Torabi, Brian P. Eliceiri, Gerald D. Silverberg, Conrad E. Johanson
Publikováno v:
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-10 (2018)
Abstract Background In Alzheimer’s disease, there are striking changes in CSF composition that relate to altered choroid plexus (CP) function. Studying CP tissue gene expression at the blood–cerebrospinal fluid barrier could provide further insig
Externí odkaz:
https://doaj.org/article/e771b953e8ea41768f40edc546e2d687
Autor:
Courtney J. Mercadante, Milankumar Prajapati, Jignesh H. Parmar, Heather L. Conboy, Miriam E. Dash, Michael A. Pettiglio, Carolina Herrera, Julia T. Bu, Edward G. Stopa, Pedro Mendes, Thomas B. Bartnikas
Publikováno v:
Haematologica, Vol 104, Iss 4 (2019)
The current paradigm in the field of mammalian iron biology states that body iron levels are determined by dietary iron absorption, not by iron excretion. Iron absorption is a highly regulated process influenced by iron levels and other factors. Iron
Externí odkaz:
https://doaj.org/article/73f845f0602f4f469a48e40f161dfe90
Autor:
Brian R. Ott, Richard N. Jones, Lori A. Daiello, Suzanne M. de la Monte, Edward G. Stopa, Conrad E. Johanson, Charles Denby, Paula Grammas
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Background: The pathophysiology underlying altered blood-cerebrospinal fluid barrier (BCSFB) function in Alzheimer's disease (AD) is unknown but may relate to endothelial cell activation and cytokine mediated inflammation.Methods: Cerebrospinal fluid
Externí odkaz:
https://doaj.org/article/89cdffa1cdd74c17b913398e9c3a9283
Autor:
Diana Klakotskaia, Cansu Agca, Rachel A Richardson, Edward G Stopa, Todd R Schachtman, Yuksel Agca
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195469 (2018)
Transgenic rat models of Alzheimer's disease were used to examine differences in memory and brain histology. Double transgenic female rats (APP+PS1) over-expressing human amyloid precursor protein (APP) and presenilin 1 (PS1) and single transgenic ra
Externí odkaz:
https://doaj.org/article/1ac8b47461b74df388734eaf96521b84
Publikováno v:
Journal of Alzheimer's Disease. 73:529-541
Alzheimer's disease (AD) is one of the most devastating and costly diseases, and prevalence of AD increases with age. Furthermore, females are twice as likely to suffer from AD compared to males. The cessation of reproductive steroid hormone producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a5616279b5105b73e89774ab70c989
https://doi.org/10.3233/jad-190935
https://doi.org/10.3233/jad-190935
Autor:
Michael Punsoni, Joseph H. Friedman, Dong Fang Yang, Murray B. Resnick, Edward G. Stopa, John E. Donahue
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 27:543-548
Gastrointestinal (GI) symptoms are common in Parkinson disease (PD), often preceding neurological manifestations; however, early diagnostic utility of GI biopsies remains controversial. Studies suggest aberrant deposition of alpha-synuclein (α-syn)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab449d17413588b41d7610708bce202
https://doi.org/10.1097/pai.0000000000000613
https://doi.org/10.1097/pai.0000000000000613
Autor:
Steven S. Meng, Barbara S. Stonestreet, Jiyong Zhang, Sayumi Imamura, Hidenori Wake, Boram Kim, Xiaodi Chen, Edward G. Stopa, Kwame Adjepong, Masahiro Nishibori, Siddhant Jaitpal
Publikováno v:
Experimental Neurology. 311:1-14
Inflammation contributes to neonatal brain injury. Pro-inflammatory cytokines represent key inflammatory meditators in neonatal hypoxic-ischemic (HI) brain injury. The high mobility group box-1 (HMGB1) protein is a nuclear protein with pro-inflammato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fdafef7da202aa0293ea77fbc65992
https://doi.org/10.1016/j.expneurol.2018.09.007
https://doi.org/10.1016/j.expneurol.2018.09.007
Autor:
Michael A. Pettiglio, Julia T. Bu, Jignesh H. Parmar, Edward G. Stopa, Carolina Herrera, Courtney J. Mercadante, Milankumar Prajapati, Miriam E. Dash, Pedro Mendes, Thomas B. Bartnikas, Heather L. Conboy
Publikováno v:
Haematologica
The current paradigm in the field of mammalian iron biology states that body iron levels are determined by dietary iron absorption, not by iron excretion. Iron absorption is a highly regulated process influenced by iron levels and other factors. Iron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f8f233a73aaeb66cdc39de7836e966
http://europepmc.org/articles/PMC6442972
http://europepmc.org/articles/PMC6442972
Autor:
Molly E. Church, Charles H. Vite, Edward G. Stopa, Melissa D. Sánchez, Gary P. Swain, Guadalupe Ceja, Megan McGeehan, Charles-Antoine Assenmacher, Amit Bar-Or, Priscilla Farias, Jorge I. Alvarez, Miles C Miller
Publikováno v:
J Immunol
Multiple sclerosis (MS) is an idiopathic demyelinating disease in which meningeal inflammation correlates with accelerated disease progression. The study of meningeal inflammation in MS has been limited because of constrained access to MS brain/spina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a848dfad8735ffc2cc4947d321c6c8
https://pubmed.ncbi.nlm.nih.gov/34162727
https://pubmed.ncbi.nlm.nih.gov/34162727