Zobrazeno 1 - 10
of 1 330
pro vyhledávání: '"G. Stief"'
Autor:
Alexander Tamalunas, Amin Wendt, Florian Springer, Victor Vigodski, Moritz Trieb, Nikolaus Eitelberger, Henrik Poth, Anna Ciotkowska, Beata Rutz, Sheng Hu, Heiko Schulz, Stephan Ledderose, Nina Rogenhofer, Thomas Kolben, Elfriede Nössner, Christian G. Stief, Martin Hennenberg
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117066- (2024)
Background: The immunomodulatory imide drugs (IMiDs) thalidomide, lenalidomide and pomalidomide may exhibit therapeutic efficacy in the prostate. In lower urinary tract symptoms (LUTS), voiding and storage disorders may arise from benign prostate hyp
Externí odkaz:
https://doaj.org/article/eab28798959146aea299757a14c1f57d
Autor:
A. E. Muderrisoglu, A. Ciotkowska, B. Rutz, S. Hu, S. Qian, A. Tamalunas, C. G. Stief, M. Hennenberg
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionMirabegron is available for treatment of overactive bladder (OAB). However, mechanisms underlying symptom improvements and long-term effects on bladder smooth muscle cells are uncertain. Contractility and growth of bladder smooth muscle c
Externí odkaz:
https://doaj.org/article/3dabeb2b799941a09f84a4df421513e9
Autor:
Severin Rodler, Karl-Friedrich Kowalewski, Henriette Scheibert, Moritz Bensel, Leo Federico Stadelmeier, Amelie Styn, Ines Rivero Belenchon, Mark Taratkin, Stefano Puliatti, Juan Gomez Rivas, Alessandro Veccia, Pietro Piazza, Enrico Checcucci, Maurice S. Michel, Christian G. Stief, Giovanni Cacciamani
Publikováno v:
European Urology Open Science, Vol 55, Iss , Pp 23-27 (2023)
Digital therapeutics (DTx) are a new class of intervention involving evidence-based software applications and have been used in neurology and psychiatry. To assess the potential of DTx in urology, we conducted a survey to assess the current prevalenc
Externí odkaz:
https://doaj.org/article/1857e96d6d374e9290956cfc064c2454
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7468 (2024)
The β3-adrenoceptor agonist mirabegron is available for the treatment of storage symptoms of overactive bladder, including frequency, urgency, and incontinence. The off-target effects of mirabegron include binding to α1-adrenoceptors, which are cen
Externí odkaz:
https://doaj.org/article/0c1ae26c70194cbfbb6eaa9345adfc9d
Autor:
Severin Rodler, Can Aydogdu, Isabel Brinkmann, Elena Berg, Rega Kopliku, Melanie Götz, Troya Ivanova, Alexander Tamalunas, Gerald B. Schulz, Volker Heinemann, Christian G. Stief, Jozefina Casuscelli
Publikováno v:
Cancers, Vol 16, Iss 12, p 2246 (2024)
Immune checkpoint inhibitor (ICI) therapies have been established as the standard-of-care in various uro-oncological cancers. Immune-related adverse events (irAEs) are frequent, but their degree rarely leads to the discontinuation of immunotherapies.
Externí odkaz:
https://doaj.org/article/bffaab1b44444e21aadf693c492b4f49
Autor:
Nikolaos Pyrgidis, Marco Moschini, Lazaros Tzelves, Bhaskar K. Somani, Patrick Juliebø-Jones, Francesco Del Giudice, Laura S. Mertens, Renate Pichler, Yannic Volz, Benedikt Ebner, Lennert Eismann, Marie Semmler, Benjamin Pradere, Francesco Soria, Christian G. Stief, Gerald B. Schulz
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 12, p 3531 (2024)
Background: Photodynamic diagnosis (PDD) during transurethral resection of bladder tumor (TURBT) is guideline recommended, as it improves bladder cancer detection rates. However, the extent to which PDD is implemented in everyday clinical practice ha
Externí odkaz:
https://doaj.org/article/df1362d1e0a845a09e7a8709b6c3ea46
Autor:
Alexander Tamalunas, Can Aydogdu, Lena M. Unterrainer, Melanie Schott, Severin Rodler, Stephan Ledderose, Gerald B. Schulz, Christian G. Stief, Jozefina Casuscelli
Publikováno v:
Cancers, Vol 16, Iss 8, p 1536 (2024)
Background: Our study endeavors to elucidate the clinical implications of PD-L1 positivity in individuals afflicted with advanced urothelial carcinoma of the bladder (UCB). Methods: Patients with advanced UCB were prospectively enrolled following a r
Externí odkaz:
https://doaj.org/article/525a9133d1c44054a6f7ca54bb66cb72
Autor:
Yuhan Liu, Ruixiao Wang, Ru Huang, Beata Rutz, Anna Ciotkowska, Alexander Tamalunas, Sheng Hu, Moritz Trieb, Raphaela Waidelich, Frank Strittmatter, Christian G. Stief, Martin Hennenberg
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: NUAKs promote myosin light chain phosphorlyation, actin organization, proliferation and suppression of cell death in non-muscle cells, which are critical for smooth muscle contraction and growth. In benign prostatic hyperplasia (BPH), con
Externí odkaz:
https://doaj.org/article/c74fe9236a454d2b979559fe7c93d1a0
Autor:
Dorothea Strobach, Lisa Haimerl, Hanna Mannell, Christian G. Stief, Alexander Karl, Tobias Grimm, Alexander Buchner
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 21, p 6749 (2023)
We aimed to characterize non-oncologic chronic drug therapy of bladder cancer (BC) patients and evaluate a possible impact on recurrence-free (RFS) and cancer-specific survival (CSS). Patients with a first diagnosis (FD) of BC or radical cystectomy (
Externí odkaz:
https://doaj.org/article/f0c9e95e852240b7a05653d3e87bac62
Autor:
Irina Dankova, Nikolaos Pyrgidis, Maksim Tishukov, Efstratia Georgiadou, Meletios P. Nigdelis, Erich-Franz Solomayer, Julian Marcon, Christian G. Stief, Dimitrios Hatzichristou
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2919 (2023)
Introduction: There is no clear evidence in the literature that platelet-rich plasma (PRP) injections improve female sexual dysfunction (FSD) and female stress urinary incontinence (SUI). Objectives: A systematic review was performed to study the eff
Externí odkaz:
https://doaj.org/article/54a71bbaf63749119f95716ec1315cf8