Zobrazeno 1 - 10
of 433
pro vyhledávání: '"G. Speit"'
Publikováno v:
Cytogenetic and Genome Research. 91:261-266
Our previous results indicated a close relationship between the presence of a BRCA1 mutation in lymphocytes and hypersensitivity for the induction of micronuclei by gamma irradiation and hydrogen peroxide (H2O2). Comparative investigations with the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6389bb0052841359be3b5735911ecee
https://doi.org/10.1159/000056855
https://doi.org/10.1159/000056855
Publikováno v:
Mutagenesis. 9:269-272
The single cell gel electrophoresis (SCG) assay (comet assay) is a sensitive technique for detecting the presence of DNA strand-breaks and alkali-labile damage in individual cells. This technique was used to study peripheral blood cells from three vo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d6c2f7f0a13bcbdb20186d72a272d9
https://doi.org/10.1093/mutage/9.3.269
https://doi.org/10.1093/mutage/9.3.269
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 291:223-297
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e38965e50fc97f35b003138f374fef74
https://doi.org/10.1016/0165-1161(93)90163-t
https://doi.org/10.1016/0165-1161(93)90163-t
Publikováno v:
Cytogenetic and genome research. 104(1-4)
Chromosomal mutagen sensitivity is a common feature of cells from patients with different kinds of cancer. A portion of breast cancer patients also shows an elevated sensitivity to the induction of chromosome damage in cells exposed to ionizing radia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd1e021a93fd548f38057c5bb9950df
https://pubmed.ncbi.nlm.nih.gov/15162060
https://pubmed.ncbi.nlm.nih.gov/15162060
Autor:
A, Hartmann, E, Agurell, C, Beevers, S, Brendler-Schwaab, B, Burlinson, P, Clay, A, Collins, A, Smith, G, Speit, V, Thybaud, R R, Tice
Publikováno v:
Mutagenesis. 18(1)
The in vivo alkaline single cell gel electrophoresis assay, hereafter the Comet assay, can be used to investigate the genotoxicity of industrial chemicals, biocides, agrochemicals and pharmaceuticals. The major advantages of this assay include the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79d7e34be5c42029f915bc7e2581a242
https://pubmed.ncbi.nlm.nih.gov/12473734
https://pubmed.ncbi.nlm.nih.gov/12473734
Publikováno v:
Mutation research. 471(1-2)
We recently showed that treatment of V79 cells with hyperbaric oxygen (HBO) efficiently induced DNA effects in the comet assay and chromosomal damage in the micronucleus test (MNT), but did not lead to gene mutations at the hprt locus. Using the come
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3c7ab021c9ede7750e934a705bea11e
https://pubmed.ncbi.nlm.nih.gov/11080664
https://pubmed.ncbi.nlm.nih.gov/11080664
Publikováno v:
Cancer research. 60(2)
Enhanced sensitivity to the chromosome-damaging effects of ionizing radiation is a feature of many cancer-predisposing conditions. It has been suggested that women with breast cancer are deficient in the repair of radiation-induced DNA damage. We hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2f8612d371d4233b333960210e0ca26
https://pubmed.ncbi.nlm.nih.gov/11479238
https://pubmed.ncbi.nlm.nih.gov/11479238
Autor:
G, Speit, A, Hartmann
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 113
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a05018976225c44fb0f3d9d7b87bbfc4
https://pubmed.ncbi.nlm.nih.gov/10443422
https://pubmed.ncbi.nlm.nih.gov/10443422
Publikováno v:
International journal of sports medicine. 17(6)
The single cell gel electrophoresis (SCG) assay was used to compare the occurrence of DNA damage in peripheral white blood cells in 6 trained (TR) and 5 untrained (UT) men after exhaustive exercise. The subjects completed an incremental treadmill tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7381131b08b821f74c8ff8ca705621
https://pubmed.ncbi.nlm.nih.gov/8884412
https://pubmed.ncbi.nlm.nih.gov/8884412
Publikováno v:
Radiation research. 143(2)
The radiosensitive Chinese hamster cell line XR-V15B was used to study the effect of decreased rejoining of DNA double-strand breaks (DSBs) on gene mutations and chromosome aberrations. XR-V15B cells are hypersensitive to the cytotoxic effects of neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29905998778bb152d2e21173ae1a7cf7
https://pubmed.ncbi.nlm.nih.gov/7631007
https://pubmed.ncbi.nlm.nih.gov/7631007