Zobrazeno 1 - 10
of 81
pro vyhledávání: '"G. Spassov"'
Publikováno v:
Sensors, Vol 24, Iss 17, p 5677 (2024)
A sequential injection analysis method for the determination of glutathione (GSH) in pharmaceuticals has been developed. It is based on the reduction of the Cu(II)-neocuproine complex by GSH and the formation of an orange-yellow colored Cu(I)-neocupr
Externí odkaz:
https://doaj.org/article/df918a31529942efa0af30bf2fab681e
Publikováno v:
Sensors, Vol 24, Iss 2, p 312 (2024)
New sequential injection analysis (SIA) methods with optical sensing for the determination of N-acetyl-L-cysteine ethyl ester (NACET) have been developed and optimized. NACET is a potential drug and antioxidant with advantageous pharmacokinetics. The
Externí odkaz:
https://doaj.org/article/8b9a70b4fc7b41b48aadf78ddca0503a
Autor:
Christin Wenzel, Sashko G Spassov, Jörg Haberstroh, Johannes Spaeth, Stefan Schumann, Johannes Schmidt
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0293215 (2023)
Large animal models are frequently used to investigate new medical approaches. In most cases, animals are kept under general anesthesia and mandatory mechanical ventilation during the experiments. However, in some situations assisted spontaneous brea
Externí odkaz:
https://doaj.org/article/4192ee21f50a472c9183804a2bc2410f
Autor:
Sashko G. Spassov, Simone Faller, Andreas Goeft, Marc-Nicolas A. Von Itter, Andreas Birkigt, Peter Meyerhoefer, Andreas Ihle, Raphael Seiler, Stefan Schumann, Alexander Hoetzel
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 1001 (2022)
Hydrogen sulfide (H2S) protects against stretch-induced lung injury. However, the impact of H2S on individual cells or their crosstalk upon stretch remains unclear. Therefore, we addressed this issue in vitro using relevant lung cells. We have explor
Externí odkaz:
https://doaj.org/article/ab3613726e69471c94ae3c3456ca1a48
Autor:
Julie Wagner, Karl M Strosing, Sashko G Spassov, Ziwei Lin, Helen Engelstaedter, Sabine Tacke, Alexander Hoetzel, Simone Faller
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192896 (2018)
Mechanical ventilation is a life-saving clinical treatment but it can induce or aggravate lung injury. New therapeutic strategies, aimed at reducing the negative effects of mechanical ventilation such as excessive production of reactive oxygen specie
Externí odkaz:
https://doaj.org/article/2ba8a02e6bd64ef7901e0377cdeb14a4
Autor:
Nan Wu, M. Inês G.S. Almeida, Silvia Simeonova, Tony G. Spassov, Antoan Rangelov, Robert W. Cattrall, Maria Datcheva, Spas D. Kolev
Publikováno v:
Journal of Membrane Science. 668:121249
Autor:
Simone Faller, Florian Hausler, Andreas Goeft, Marc-Nicolas André von Itter, Veronica Gyllenram, Alexander Hoetzel, Sashko G. Spassov
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Transmigration and activation of neutrophils in the lung reflect key steps in the progression of acute lung injury (ALI). It is known that hydrogen sulfide (H2S) can limit neutrophil activation, but the respective mechanisms remain elusive. Here, we
Autor:
Julie Wagner, Karl M Strosing, Sashko G Spassov, Ziwei Lin, Helen Engelstaedter, Sabine Tacke, Alexander Hoetzel, Simone Faller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0192896 (2018)
PLoS ONE, Vol 13, Iss 2, p e0192896 (2018)
Mechanical ventilation is a life-saving clinical treatment but it can induce or aggravate lung injury. New therapeutic strategies, aimed at reducing the negative effects of mechanical ventilation such as excessive production of reactive oxygen specie
Publikováno v:
Process Biochemistry. 34:231-237
The product (S)-p-chlorodiphenylmethanol is obtained through stereoselective reduction of p-chlorobenzophenone using Debaryomyces marama cells, immobilized on Raschig rings. This process involved continuous fermentations in bioreactors for a period o
Publikováno v:
Canadian Journal of Microbiology. 45:217-222
The keratinase production by the thermophilic actinomycete strain Thermoactinomyces candidus was induced by sheep wool as the sole source of carbon and nitrogen in the cultivation medium. For complete digestion of wool by the above strain, both kerat